A novel Bcl-2 related gene, Bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow
about
The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosisIdentification of a polymorphic gene, BCL2A1, encoding two novel hematopoietic lineage-specific minor histocompatibility antigensTargeting BCL2-Proteins for the Treatment of Solid TumoursBAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial poreExtracellular BCL2 proteins are danger-associated molecular patterns that reduce tissue damage in murine models of ischemia-reperfusion injuryA1/Bfl-1 in leukocyte development and cell deathEstrogen stimulates microglia and brain recovery from hypoxia-ischemia in normoglycemic but not diabetic female mice.BCL2A1a over-expression in murine hematopoietic stem and progenitor cells decreases apoptosis and results in hematopoietic transformation.NF-kappa B-dependent assembly of an enhanceosome-like complex on the promoter region of apoptosis inhibitor Bfl-1/A1Epstein-Barr virus nuclear antigen 2 trans-activates the cellular antiapoptotic bfl-1 gene by a CBF1/RBPJ kappa-dependent pathway.Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosisBak Conformational Changes Induced by Ligand Binding: Insight into BH3 Domain Binding and Bak Homo-OligomerizationDNA-damage response network at the crossroads of cell-cycle checkpoints, cellular senescence and apoptosisPhenotype frequencies of autosomal minor histocompatibility antigens display significant differences among populationsBCL-2 Antagonism to Target the Intrinsic Mitochondrial Pathway of Apoptosis.Activation of human monocytes induces differential resistance to apoptosis with rapid down regulation of caspase-8/FLICE.The C-terminal domain of A1/Bfl-1 regulates its anti-inflammatory function in human endothelial cellsNuclear factor kappa B-dependent activation of the antiapoptotic bfl-1 gene by the Epstein-Barr virus latent membrane protein 1 and activated CD40 receptor.Mimicking the BH3 domain to kill cancer cellsBCL2A1: the underdog in the BCL2 family.Targeting the B-cell lymphoma/leukemia 2 family in cancer.The bfl-1 gene is transcriptionally upregulated by the Epstein-Barr virus LMP1, and its expression promotes the survival of a Burkitt's lymphoma cell lineThe anti-apoptotic Bcl-2 family protein A1/Bfl-1 regulates neutrophil survival and homeostasis and is controlled via PI3K and JAK/STAT signaling.Pharmacological manipulation of Bcl-2 family members to control cell death.To live or die: a critical decision for the lung.Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor.Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment.
P2860
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P2860
A novel Bcl-2 related gene, Bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow
description
1995 nî lūn-bûn
@nan
1995 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A novel Bcl-2 related gene, Bf ...... ially expressed in bone marrow
@ast
A novel Bcl-2 related gene, Bf ...... ially expressed in bone marrow
@en
A novel Bcl-2 related gene, Bf ...... ially expressed in bone marrow
@nl
type
label
A novel Bcl-2 related gene, Bf ...... ially expressed in bone marrow
@ast
A novel Bcl-2 related gene, Bf ...... ially expressed in bone marrow
@en
A novel Bcl-2 related gene, Bf ...... ially expressed in bone marrow
@nl
prefLabel
A novel Bcl-2 related gene, Bf ...... ially expressed in bone marrow
@ast
A novel Bcl-2 related gene, Bf ...... ially expressed in bone marrow
@en
A novel Bcl-2 related gene, Bf ...... ially expressed in bone marrow
@nl
P2093
P1433
P1476
A novel Bcl-2 related gene, Bf ...... ially expressed in bone marrow
@en
P2093
P304
P407
P577
1995-11-01T00:00:00Z