Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis - Wikidata - awgldk - TriplyDB

Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis

Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis

http://www.wikidata.org/entity/Q28284388

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Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine Antimicrobial activity of pentacyclic triterpenes isolated from Acacia mellifera Phytochemicals and potential health effects of Sambucus williamsii Hance (Jiegumu)"Ziziphus jujuba": A red fruit with promising anticancer activities Discovery of new anticancer agents from higher plants Triterpenoids amplify anti-tumoral effects of mistletoe extracts on murine B16.f10 melanoma in vivo Optimization of Invasion-Specific Effects of Betulin Derivatives on Prostate Cancer Cells through Lead Development.Betulinic acid and its derivatives: a patent review (2008-2013).Synthesis of antitumor-active betulinic acid-derived hydroxypropargylamines by copper-catalyzend mannich reactions.Conversions at C-30 of glycyrrhetinic acid and their impact on antitumor activity.Synthesis, encapsulation and antitumor activity of new betulin derivatives.Cytotoxic constituents from the stem bark of Dichapetalum gelonioides collected in the Philippines Is translational research compatible with preclinical publication strategies?Antineoplastic agents from natural sources: achievements and future directions.Determination of the triterpenoid, betulinic acid, in Doliocarpus schottianus by HPLC.Signalling responses linked to betulinic acid-induced apoptosis are antagonized by MEK inhibitor U0126 in adherent or 3D spheroid melanoma irrespective of p53 status.In vitro and in vivo protective effects of proteoglycan isolated from mycelia of Ganoderma lucidum on carbon tetrachloride-induced liver injury.Effect of betulinic acid on the regulation of Hiwi and cyclin B1 in human gastric adenocarcinoma AGS cells.Anti-leishmanial activity of betulin derivatives.The continuing search for antitumor agents from higher plants Betulinic acid in complex with a gamma-cyclodextrin derivative decreases proliferation and in vivo tumor development of non-metastatic and metastatic B164A5 cells.Bacoside A Induces Tumor Cell Death in Human Glioblastoma Cell Lines through Catastrophic Macropinocytosis.Betulinic acid suppresses constitutive and TNFalpha-induced NF-kappaB activation and induces apoptosis in human prostate carcinoma PC-3 cells.Synthesis and evaluation of library of betulin derivatives against the botulinum neurotoxin A protease.Betulinic acid suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase SHP-1 in human multiple myeloma cells.Suppression of STAT3 and HIF-1 alpha mediates anti-angiogenic activity of betulinic acid in hypoxic PC-3 prostate cancer cells.Biotransformation of the antimelanoma agent betulinic acid by Bacillus megaterium ATCC 13368.Betulinic acid induces apoptosis and inhibits hedgehog signalling in rhabdomyosarcoma.The natural triterpene 3β,6β,16β-trihydroxy-lup-20(29)-ene obtained from the flowers of Combretum leprosum induces apoptosis in MCF-7 breast cancer cells Proteomic investigation into betulinic acid-induced apoptosis of human cervical cancer HeLa cells Anticancer Potential of Aqueous Ethanol Seed Extract of Ziziphus mauritiana against Cancer Cell Lines and Ehrlich Ascites Carcinoma Pharmacognosy in the 21st century.Immunomodulatory effects of betulinic acid from the bark of white birch on mice.Betulinic acid inhibits autophagic flux and induces apoptosis in human multiple myeloma cells in vitro Improving physical properties via C-H oxidation: chemical and enzymatic approaches Antiproliferative activity and apoptosis-inducing mechanism of constituents from Toona sinensis on human cancer cells Betulinic acid selectively increases protein degradation and enhances prostate cancer-specific apoptosis: possible role for inhibition of deubiquitinase activity Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer.A potent tumoricidal co-drug 'Bet-CA'--an ester derivative of betulinic acid and dichloroacetate selectively and synergistically kills cancer cells Hypericum lanceolatum (Hypericaceae) as a potential source of new anti-malarial agents: a bioassay-guided fractionation of the stem bark.

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Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis

http://www.wikidata.org/entity/Q28284388

description

1995 nî lūn-bûn

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1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1995 թվականի հոտեմբերին հրատարակված գիտական հոդված

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1995年の論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年论文

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A D Kinghorn

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C W Beecher

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D M Brown

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E Pisha

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G A Cordell

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H Chai

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H H Fong

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I S Lee

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N R Farnsworth

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T E Chagwedera

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scholarly article

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4050797

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10.1038/NM1095-1046

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10

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1011112468

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7489361

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