The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor
about
Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 familyThe ciliary neurotrophic factor receptor alpha component induces the secretion of and is required for functional responses to cardiotrophin-like cytokineCloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transductionCloning and characterization of a specific receptor for mouse oncostatin MInterleukin-6-type cytokine signalling through the gp130/Jak/STAT pathwayCrystal structure of a cytokine-binding region of gp130.Phosphorylation of the human leukemia inhibitory factor (LIF) receptor by mitogen-activated protein kinase and the regulation of LIF receptor function by heterologous receptor activationMouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathwayActivation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130Multiple regions within the cytoplasmic domains of the leukemia inhibitory factor receptor and gp130 cooperate in signal transduction in hepatic and neuronal cellsAs the world grows: contraception in the 21st centuryc-Cbl-dependent monoubiquitination and lysosomal degradation of gp130Molecular cloning of integrin-associated protein: an immunoglobulin family member with multiple membrane-spanning domains implicated in alpha v beta 3-dependent ligand bindingOncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cellsAIDS-associated Kaposi's sarcoma (KS) cells express oncostatin M (OM)-specific receptor but not leukemia inhibitory factor/OM receptor or interleukin-6 receptor. Complete block of OM-induced KS cell growth and OM binding by anti-gp130 antibodiesA herpes simplex virus-derived replicative vector expressing LIF limits experimental demyelinating disease and modulates autoimmunityLeukemia inhibitory factor (LIF)Stimulation of leukemia inhibitory factor receptor degradation by extracellular signal-regulated kinaseStructural and functional studies on the leukemia inhibitory factor receptor (LIF-R): gene and soluble form of LIF-R, and cytoplasmic domain of LIF-R required for differentiation and growth arrest of myeloid leukemic cellsA novel oncostatin M-inducible gene OIG37 forms a gene family with MyD118 and GADD45 and negatively regulates cell growthDefinition of receptor binding sites on human interleukin-11 by molecular modeling-guided mutagenesisCiliary neurotrophic factor induces acute-phase protein expression in hepatocytesA functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptorGPL, a novel cytokine receptor related to GP130 and leukemia inhibitory factor receptorSignaling pathways recruited by the cardiotrophin-like cytokine/cytokine-like factor-1 composite cytokine: specific requirement of the membrane-bound form of ciliary neurotrophic factor receptor alpha componentAn unexpected biochemical and functional interaction between gp130 and the EGF receptor family in breast cancer cellsInfluence of subunit combinations on signaling by receptors for oncostatin M, leukemia inhibitory factor, and interleukin-6Signaling of type II oncostatin M receptorBox 3-independent signaling mechanisms are involved in leukemia inhibitory factor receptor alpha- and gp130-mediated stimulation of mitogen-activated protein kinase. Evidence for participation of multiple signaling pathways which converge at RasDistinct roles for leukemia inhibitory factor receptor alpha-chain and gp130 in cell type-specific signal transductionCloning and expression of an alternatively spliced mRNA encoding a soluble form of the human interleukin-6 signal transducer gp130Identification of an upstream enhancer within a functional promoter of the human leukemia inhibitory factor receptor gene and its alternative promoter usageTransmembrane domain of gp130 contributes to intracellular signal transduction in hepatic cellsFunctional expression of soluble human interleukin-11 (IL-11) receptor alpha and stoichiometry of in vitro IL-11 receptor complexes with gp130Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptorFetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer.Oncostatin M is a potent stimulator of alpha1-antitrypsin secretion in lung epithelial cells: modulation by transforming growth factor-beta and interferon-gammaPhosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6Phosphorylation and internalization of gp130 occur after IL-6 activation of Jak2 kinase in hepatocytesA genetic expression profile associated with oral cancer identifies a group of patients at high risk of poor survival.
P2860
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P2860
The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor
description
1992 nî lūn-bûn
@nan
1992 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի մարտին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
The IL-6 signal transducer, gp ...... converter for the LIF receptor
@ast
The IL-6 signal transducer, gp ...... converter for the LIF receptor
@en
The IL-6 signal transducer, gp ...... converter for the LIF receptor
@nl
type
label
The IL-6 signal transducer, gp ...... converter for the LIF receptor
@ast
The IL-6 signal transducer, gp ...... converter for the LIF receptor
@en
The IL-6 signal transducer, gp ...... converter for the LIF receptor
@nl
prefLabel
The IL-6 signal transducer, gp ...... converter for the LIF receptor
@ast
The IL-6 signal transducer, gp ...... converter for the LIF receptor
@en
The IL-6 signal transducer, gp ...... converter for the LIF receptor
@nl
P2093
P356
P1433
P1476
The IL-6 signal transducer, gp ...... converter for the LIF receptor
@en
P2093
D J Friend
D P Gearing
J McGourty
K K Brasher
M R Comeau
S D Gimpel
P304
P356
10.1126/SCIENCE.1542794
P407
P577
1992-03-13T00:00:00Z