M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
about
Dominant-negative effect of truncated mannose 6-phosphate/insulin-like growth factor II receptor species in cancerImprinting of the human L3MBTL gene, a polycomb family member located in a region of chromosome 20 deleted in human myeloid malignanciesMannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interactionDecreased expression of the mannose 6-phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cellsDown-regulation of the M6P/IGF-II receptor increases cell proliferation and reduces apoptosis in neonatal rat cardiac myocytesM6P/IGF2R loss of heterozygosity in head and neck cancer associated with poor patient prognosisEpigenetic regulation of insulin-like growth factor axis in hepatocellular carcinomaTargeting the insulin-like growth factor pathway in hepatocellular carcinomaInsulin-like growth factor system in cancer: novel targeted therapiesMannose 6-phosphate receptors: new twists in the taleRecombinant human acid sphingomyelinase as an adjuvant to sorafenib treatment of experimental liver cancerRetinoic acid alters the intracellular trafficking of the mannose-6-phosphate/insulin-like growth factor II receptor and lysosomal enzymesEnvironmental epigenomics and disease susceptibilityInsulin and insulin-like growth factor signalling in neoplasiaLoss of heterozygosity of M6P/IGF2R gene is an early event in the development of prostate cancer.Genomic imprinting: implications for human disease.A patient with Simpson-Golabi-Behmel syndrome and hepatocellular carcinoma.Mannose-6-phosphate/insulin-like growth factor-II receptor is a receptor for retinoic acid.Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma.Imprinted genes as potential genetic and epigenetic toxicologic targetsThe IGF axis and hepatocarcinogenesis.Cancer gene discovery in hepatocellular carcinomaSomatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomasIGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage.Human hepatocellular carcinoma is characterized by a highly consistent pattern of genomic imbalances, including frequent loss of 16q23.1-24.1.Biology of transforming growth factor beta in hepatocarcinogenesis.The GH-IGF-SST system in hepatocellular carcinoma: biological and molecular pathogenetic mechanisms and therapeutic targets.Modulation of insulin/IGFs pathways by sirtuin-7 inhibition in drug-induced chemoreistanceMolecular aspects of hepatic carcinogenesis.Maternal transmission of a humanised Igf2r allele results in an Igf2 dependent hypomorphic and non-viable growth phenotypeAntagonists of growth hormone-releasing hormone inhibit the growth of U-87MG human glioblastoma in nude mice.Monitoring microarray-based gene expression profile changes in hepatocellular carcinomaMolecular carcinogenesis of hepatocellular carcinoma and intrahepatic cholangiocarcinoma: one step closer to personalized medicine?Expression of the insulin-like growth factors and their receptors in adenocarcinoma of the colonKeys to the hidden treasures of the mannose 6-phosphate/insulin-like growth factor 2 receptor.Tissue-specific inactivation of murine M6P/IGF2R.Nuclear accumulation of mutated beta-catenin in hepatocellular carcinoma is associated with increased cell proliferationQuantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation.Expression of IGF-II in early experimental hepatocellular carcinomas and its significance in early diagnosis.Treatment of hematologic malignancies and solid tumors by inhibiting IGF receptor signaling.
P2860
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P2860
M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
description
1995 nî lūn-bûn
@nan
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
@ast
M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
@en
M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
@nl
type
label
M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
@ast
M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
@en
M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
@nl
prefLabel
M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
@ast
M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
@en
M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
@nl
P2093
P2860
P356
P1433
P1476
M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
@en
P2093
A T De Souza
G R Hankins
M K Washington
R L Jirtle
P2860
P2888
P356
10.1038/NG1295-447
P407
P577
1995-12-01T00:00:00Z