Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks - Wikidata - awgldk - TriplyDB

Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

http://www.wikidata.org/entity/Q28286203

about

Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island Radiation-induced alterations in histone modification patterns and their potential impact on short-term radiation effects Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4 RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repair MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks Regulation of TIP60 by ATF2 modulates ATM activation PALB2 regulates recombinational repair through chromatin association and oligomerization VRK1 chromatin kinase phosphorylates H2AX and is required for foci formation induced by DNA damage The histone demethylase LSD1/KDM1A promotes the DNA damage response Epigenetic modifications in double-strand break DNA damage signaling and repair Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics Targeting cancer using KAT inhibitors to mimic lethal knockouts The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic target Chromatin perturbations during the DNA damage response in higher eukaryotes Functional Role of NBS1 in Radiation Damage Response and Translesion DNA Synthesis Substrate recognition and function of the R2TP complex in response to cellular stress ATP-dependent chromatin remodeling complexes as novel targets for cancer therapy Metabolic modulation of chromatin: implications for DNA repair and genomic integrity Crosstalk between ubiquitin and other post-translational modifications on chromatin during double-strand break repair Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis.The MYST family histone acetyltransferase regulates gene expression and cell cycle in malaria parasite Plasmodium falciparum Acetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and Cancer Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks PALB2: the hub of a network of tumor suppressors involved in DNA damage responses The HINT1 tumor suppressor regulates both gamma-H2AX and ATM in response to DNA damage Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks An allelic series uncovers novel roles of the BRCT domain-containing protein PTIP in mouse embryonic vascular development Germline stem cell gene PIWIL2 mediates DNA repair through relaxation of chromatin Insights into the regenerative property of plant cells and their receptivity to transgenesis: wheat as a research case study.Tip60 degradation by adenovirus relieves transcriptional repression of viral transcriptional activator EIA.The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination.Destabilization of TIP60 by human papillomavirus E6 results in attenuation of TIP60-dependent transcriptional regulation and apoptotic pathway.RVB1/RVB2: running rings around molecular biology.Histone acetyltransferase Hbo1: catalytic activity, cellular abundance, and links to primary cancers Human Rvb1/Tip49 is required for the histone acetyltransferase activity of Tip60/NuA4 and for the downregulation of phosphorylation on H2AX after DNA damage.

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P2860

Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

http://www.wikidata.org/entity/Q28286203

description

2006 nî lūn-bûn

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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2006 թվականի հունվարին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Histone acetylation by Trrap-T ...... ir of DNA double-strand breaks

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Histone acetylation by Trrap-T ...... ir of DNA double-strand breaks

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Histone acetylation by Trrap-T ...... ir of DNA double-strand breaks

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Histone acetylation by Trrap-T ...... ir of DNA double-strand breaks

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Histone acetylation by Trrap-T ...... ir of DNA double-strand breaks

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Histone acetylation by Trrap-T ...... ir of DNA double-strand breaks

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Histone acetylation by Trrap-T ...... ir of DNA double-strand breaks

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Nature Cell Biology

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Histone acetylation by Trrap-T ...... ir of DNA double-strand breaks

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P2093

Cyrille Cuenin

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Hai Li

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Yun-Gui Yang

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Zdenko Herceg

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Zhao-Qi Wang

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P2860

Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction

Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo

The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins

UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation

The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc

Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4.

Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites.

Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.

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91-9

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scholarly article

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1103252

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10.1038/NCB1343

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1

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8

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Joanna I. Loizou

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2006-01-01T00:00:00Z

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7429035

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1001861805

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16341205

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