Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels
about
Neuroprotection by caffeine: time course and role of its metabolites in the MPTP model of Parkinson's diseaseUpstream deregulation of calcium signaling in Parkinson's diseaseCellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disordersChemicals possessing a neurotrophin-like activity on dopaminergic neurons in primary cultureEffects of paraxanthine and caffeine on sleep, locomotor activity, and body temperature in orexin/ataxin-3 transgenic narcoleptic miceConcordant signaling pathways produced by pesticide exposure in mice correspond to pathways identified in human Parkinson's diseaseDelayed caffeine treatment prevents nigral dopamine neuron loss in a progressive rat model of Parkinson's diseaseDifferential Effect of Caffeine Consumption on Diverse Brain Areas of Pregnant Rats.DAP12 and CD11b contribute to the microglial-induced death of dopaminergic neurons in vitro but not in vivo in the MPTP mouse model of Parkinson's diseaseRelation of 24-hour urinary caffeine and caffeine metabolite excretions with self-reported consumption of coffee and other caffeinated beverages in the general population.Emerging treatments for narcolepsy and its related disorders.Parkinson's disease: mitochondrial molecular pathology, inflammation, statins, and therapeutic neuroprotective nutrition.Health benefits of methylxanthines in neurodegenerative diseases.Autophagy inhibition by caffeine increases toxicity of methamphetamine in SH-SY5Y neuroblastoma cell line.Neuronal Ryanodine Receptors in Development and Aging.PDE5 Inhibitors as Potential Tools in the Treatment of Cystic Fibrosis.KATP channel blockade protects midbrain dopamine neurons by repressing a glia-to-neuron signaling cascade that ultimately disrupts mitochondrial calcium homeostasis.Chromatographic resolution of closely related species: drug metabolites and analogs.Treatment with A2A receptor antagonist KW6002 and caffeine intake regulate microglia reactivity and protect retina against transient ischemic damage.Impact of Coffee and Cacao Purine Metabolites on Neuroplasticity and Neurodegenerative Disease.Succinobucol, a Non-Statin Hypocholesterolemic Drug, Prevents Premotor Symptoms and Nigrostriatal Neurodegeneration in an Experimental Model of Parkinson's Disease.Ryanodine Receptors in Autophagy: Implications for Neurodegenerative Diseases?
P2860
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P2860
Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Paraxanthine, the primary meta ...... of ryanodine receptor channels
@ast
Paraxanthine, the primary meta ...... of ryanodine receptor channels
@en
Paraxanthine, the primary meta ...... of ryanodine receptor channels
@nl
type
label
Paraxanthine, the primary meta ...... of ryanodine receptor channels
@ast
Paraxanthine, the primary meta ...... of ryanodine receptor channels
@en
Paraxanthine, the primary meta ...... of ryanodine receptor channels
@nl
prefLabel
Paraxanthine, the primary meta ...... of ryanodine receptor channels
@ast
Paraxanthine, the primary meta ...... of ryanodine receptor channels
@en
Paraxanthine, the primary meta ...... of ryanodine receptor channels
@nl
P2093
P921
P356
P1476
Paraxanthine, the primary meta ...... of ryanodine receptor channels
@en
P2093
Damien Toulorge
Marc Marien
Pierre Sokoloff
Serge Guerreiro
P304
P356
10.1124/MOL.108.048207
P407
P577
2008-07-11T00:00:00Z