Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns
about
Non–coding RNA genes and the modern RNA worldThe human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosomeRecycling of the U12-type spliceosome requires p110, a component of the U6atac snRNPMinor spliceosome components are predominantly localized in the nucleusA novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.Evolutionary conservation of minor U12-type spliceosome between plants and humansBase pairing with U6atac snRNA is required for 5' splice site activation of U12-dependent introns in vivo.Conservation of functional features of U6atac and U12 snRNAs between vertebrates and higher plantsThe human Prp8 protein is a component of both U2- and U12-dependent spliceosomesDomains of human U4atac snRNA required for U12-dependent splicing in vivoMutations in U4atac snRNA, a component of the minor spliceosome, in the developmental disorder MOPD IAn intronic enhancer regulates splicing of the twintron of Drosophila melanogaster prospero pre-mRNA by two different spliceosomesU12DB: a database of orthologous U12-type spliceosomal intronsSite-specific crosslinking of mammalian U11 and u6atac to the 5' splice site of an AT-AC intronSpliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesisPseudouridine mapping in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (snRNAs) reveals that pseudouridine synthase pus1p exhibits a dual substrate specificity for U2 snRNA and tRNA.Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in DrosophilaAn early evolutionary origin for the minor spliceosomeSplicing of a rare class of introns by the U12-dependent spliceosomeThe significant other: splicing by the minor spliceosomeAssociation of TALS developmental disorder with defect in minor splicing component U4atac snRNAYeast U1 snRNP-pre-mRNA complex formation without U1snRNA-pre-mRNA base pairing.U12 intron positions are more strongly conserved between animals and plants than U2 intron positions.U12 type introns were lost at multiple occasions during evolution.Evolutionary dynamics of U12-type spliceosomal introns.AT-AC pre-mRNA splicing mechanisms and conservation of minor introns in voltage-gated ion channel genes.Genetic studies exposing the splicing events involved in herpes simplex virus type 1 latency-associated transcript production during lytic and latent infection.U1 small nuclear ribonucleoprotein and splicing inhibition by the rous sarcoma virus negative regulator of splicing element.Gene expression profiling of U12-type spliceosome mutant Drosophila reveals widespread changes in metabolic pathwaysThe U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11-59K proteinRole of the 3' splice site in U12-dependent intron splicingThe splicing of U12-type introns can be a rate-limiting step in gene expression.Correct mRNA processing at a mutant TT splice donor in FANCC ameliorates the clinical phenotype in patients and is enhanced by delivery of suppressor U1 snRNAs.U4 small nuclear RNA can function in both the major and minor spliceosomes.The role of overlapping U1 and U11 5' splice site sequences in a negative regulator of splicingA limited number of pseudouridine residues in the human atac spliceosomal UsnRNAs as compared to human major spliceosomal UsnRNAsThe intramolecular stem-loop structure of U6 snRNA can functionally replace the U6atac snRNA stem-loopFunctions of SR proteins in the U12-dependent AT-AC pre-mRNA splicing pathway.Branchpoint selection in the splicing of U12-dependent introns in vitroThe conserved central domain of yeast U6 snRNA: importance of U2-U6 helix Ia in spliceosome assembly.
P2860
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P2860
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns
description
1996 nî lūn-bûn
@nan
1996 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns
@ast
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns
@en
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns
@nl
type
label
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns
@ast
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns
@en
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns
@nl
prefLabel
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns
@ast
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns
@en
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns
@nl
P3181
P1433
P1476
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns
@en
P2093
P304
P3181
P356
10.1126/SCIENCE.273.5283.1824
P407
P577
1996-09-27T00:00:00Z