The C-terminal portion of BM-40 (SPARC/osteonectin) is an autonomously folding and crystallisable domain that binds calcium and collagen IV
about
Crystal structure and mapping by site-directed mutagenesis of the collagen-binding epitope of an activated form of BM-40/SPARC/osteonectinCharacterization of SMOC-2, a modular extracellular calcium-binding proteinFstl1 antagonizes BMP signaling and regulates ureter developmentSPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement MembraneSPARC-Dependent Cardiomyopathy in Drosophila.Structure and calcium-binding studies of calmodulin-like domain of human non-muscle α-actinin-1.Structural basis of sequence-specific collagen recognition by SPARCStructure of a novel extracellular Ca(2+)-binding module in BM-40SPARC, a matricellular glycoprotein with important biological functionsIdentification and characterization of a novel follistatin-like protein as a binding protein for the TGF-beta familyDifferential expression patterns of occ1-related genes in adult monkey visual cortex.SC1/hevin. An extracellular calcium-modulated protein that binds collagen I.Characterization of Smoc-1 uncovers two transcript variants showing differential tissue and age specific expression in Bubalus bubalis.The occ1 gene is preferentially expressed in the primary visual cortex in an activity-dependent manner: a pattern of gene expression related to the cytoarchitectonic area in adult macaque neocortex.Secreted protein acidic and rich in cysteine is a matrix scavenger chaperone.SPARC/osteonectin functions to maintain homeostasis of the collagenous extracellular matrix in the periodontal ligament.The novel SPARC family member SMOC-2 potentiates angiogenic growth factor activity.The heparin-binding activity of secreted modular calcium-binding protein 1 (SMOC-1) modulates its cell adhesion propertiesAssociation between SPARC mRNA expression, prognosis and response to neoadjuvant chemotherapy in early breast cancer: a pooled in-silico analysisExpression, functional, and structural analysis of proteins critical for otoconia developmentMatricellular homologs in the foreign body response: hevin suppresses inflammation, but hevin and SPARC together diminish angiogenesis.Anti-cancer role of SPARC, an inhibitor of adipogenesisA peptide of SPARC interferes with the interaction between caspase8 and Bcl2 to resensitize chemoresistant tumors and enhance their regression in vivoMechanisms of otoconia and otolith developmentSPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells.The glaucoma-associated olfactomedin domain of myocilin is a novel calcium binding protein.Mapping of SPARC/BM-40/osteonectin-binding sites on fibrillar collagens.Is SPARC an evolutionarily conserved collagen chaperone?A BAC transgenic mouse model to analyze the function of astroglial SPARCL1 (SC1) in the central nervous system.Cloning and expression of murine SC1, a gene product homologous to SPARC.Astrocyte-secreted matricellular proteins in CNS remodelling during development and diseaseStructural and functional characterization of the extracellular calcium-binding protein BM-40/secreted protein, acidic, rich in cysteine/osteonectin from the nematode Caenorhabditis elegans.Structural characterization of TSC-36/Flik: analysis of two charge isoforms.Structural and functional analysis of the globular domain IVa of the laminin alpha 1 chain and its impact on an adjacent RGD site.Calcium affinity, cooperativity, and domain interactions of extracellular EF-hands present in BM-40.Recombinant domain IV of perlecan binds to nidogens, laminin-nidogen complex, fibronectin, fibulin-2 and heparin.Loss of SPARC dysregulates basal lamina assembly to disrupt larval fat body homeostasis in Drosophila melanogaster.Differential modulation of cell adhesion by interaction between adhesive and counter-adhesive proteins: characterization of the binding of vitronectin to osteonectin (BM40, SPARC).Crystal structure of a pair of follistatin-like and EF-hand calcium-binding domains in BM-40.Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally but show severe age-onset cataract formation and disruption of the lens.
P2860
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P2860
The C-terminal portion of BM-40 (SPARC/osteonectin) is an autonomously folding and crystallisable domain that binds calcium and collagen IV
description
1995 nî lūn-bûn
@nan
1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The C-terminal portion of BM-4 ...... binds calcium and collagen IV
@ast
The C-terminal portion of BM-4 ...... binds calcium and collagen IV
@en
The C-terminal portion of BM-4 ...... binds calcium and collagen IV
@nl
type
label
The C-terminal portion of BM-4 ...... binds calcium and collagen IV
@ast
The C-terminal portion of BM-4 ...... binds calcium and collagen IV
@en
The C-terminal portion of BM-4 ...... binds calcium and collagen IV
@nl
prefLabel
The C-terminal portion of BM-4 ...... binds calcium and collagen IV
@ast
The C-terminal portion of BM-4 ...... binds calcium and collagen IV
@en
The C-terminal portion of BM-4 ...... binds calcium and collagen IV
@nl
P2093
P3181
P356
P1476
The C-terminal portion of BM-4 ...... binds calcium and collagen IV
@en
P2093
P304
P3181
P356
10.1006/JMBI.1995.0557
P407
P577
1995-10-20T00:00:00Z