Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders
about
Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein CCrystal structure of the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitorModulation of prothrombinase assembly and activity by phosphatidylethanolamineLocations of disulfide bonds and free cysteines in the heavy and light chains of recombinant human factor VIII (antihemophilic factor A)The tertiary structure and domain organization of coagulation factor VIIIDomain organization of membrane-bound factor VIII.Structure of the factor VIII C2 domain in a ternary complex with 2 inhibitor antibodies reveals classical and nonclassical epitopesCysteamine enhances the procoagulant activity of Factor VIII-East Hartford, a dysfunctional protein due to a light chain thrombin cleavage site mutation (arginine-1689 to cysteine)Differential proteolytic activation of factor VIII-von Willebrand factor complex by thrombinA3 domain region 1803-1818 contributes to the stability of activated factor VIII and includes a binding site for activated factor IXDimeric Organization of Blood Coagulation Factor VIII bound to Lipid Nanotubes.Crystallization and preliminary X-ray crystallographic analysis of blood coagulation factor V-activating proteinase (RVV-V) from Russell's viper venomElectron microscopy of human factor V and factor VIII: correlation of morphology with domain structure and localization of factor V activation fragments.cDNA cloning of a mouse mammary epithelial cell surface protein reveals the existence of epidermal growth factor-like domains linked to factor VIII-like sequences.Regulation of the protein C anticoagulant and antiinflammatory pathways.Lack of recombinant factor VIII B-domain induces phospholipid vesicle aggregation: implications for the immunogenicity of factor VIIIInhibition of human factor VIIIa by anti-A2 subunit antibodies.Physiological anticoagulation. Resistance to activated protein C and venous thromboembolismThe molecular basis of factor V and VIII procofactor activationBlood coagulation factors V and VIII: Molecular Mechanisms of Procofactor Activation.Investigation of hFVIII production in mammary glands of transgenic mice.Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V.The 1.7 Å X-ray crystal structure of the porcine factor VIII C2 domain and binding analysis to anti-human C2 domain antibodies and phospholipid surfacesCharacterization of an acquired inhibitor to coagulation factor V. Antibody binding to the second C-type domain of factor V inhibits the binding of factor V to phosphatidylserine and neutralizes procoagulant activity.Epidemiology of activated protein C resistance and factor v leiden mutation in the mediterranean region.A case of coagulation factor V deficiency complicated with intracranial hemorrhageCharacterization and solution structure of the factor VIII C2 domain in a ternary complex with classical and non-classical inhibitor antibodies.A phosphatidylserine binding site in factor Va C1 domain regulates both assembly and activity of the prothrombinase complex.Hemophilia A due to mutations that create new N-glycosylation sites.Mutations and a polymorphism in the factor VIII gene discovered by denaturing gradient gel electrophoresisDetailed mechanisms of the inactivation of factor VIIIa by activated protein C in the presence of its cofactors, protein S and factor V.Mapping of the factor Xa binding site on factor Va by site-directed mutagenesisHaemophilia A: database of nucleotide substitutions, deletions, insertions and rearrangements of the factor VIII geneEffective electrostatic charge of coagulation factor X in solution and on phospholipid membranes: implications for activation mechanisms and structure-function relationships of the Gla domain.Inhibition of human coagulation factor VIII by monoclonal antibodies. Mapping of functional epitopes with the use of recombinant factor VIII fragments.Structural and functional characterization of Factor VIII-delta II, a new recombinant Factor VIII lacking most of the B-domain.The pro-polypeptide of von Willebrand factor is required for the formation of a functional factor VIII-binding site on mature von Willebrand factor.The interaction between human blood-coagulation factor VIII and von Willebrand factor. Characterization of a high-affinity binding site on factor VIII.Importance of a factor VIIIc-like glycoprotein expressed in capillary endothelial cells (eFactor VIIIc) in angiogenesis.Crystallization and preliminary crystallographic characterization of three peptidic inhibitors in complex with α-thrombin.
P2860
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P2860
Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders
description
1988 nî lūn-bûn
@nan
1988 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի մարտին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Blood coagulation factors V an ...... hagic and thrombotic disorders
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Blood coagulation factors V an ...... hagic and thrombotic disorders
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Blood coagulation factors V an ...... hagic and thrombotic disorders
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type
label
Blood coagulation factors V an ...... hagic and thrombotic disorders
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Blood coagulation factors V an ...... hagic and thrombotic disorders
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Blood coagulation factors V an ...... hagic and thrombotic disorders
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prefLabel
Blood coagulation factors V an ...... hagic and thrombotic disorders
@ast
Blood coagulation factors V an ...... hagic and thrombotic disorders
@en
Blood coagulation factors V an ...... hagic and thrombotic disorders
@nl
P1433
P1476
Blood coagulation factors V an ...... hagic and thrombotic disorders
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P2093
P304
P407
P577
1988-03-01T00:00:00Z