Receptor-mediated internalization of insulin. Potential role of pp120/HA4, a substrate of the insulin receptor kinase
about
The differential effects of pp120 (Ceacam 1) on the mitogenic action of insulin and insulin-like growth factor 1 are regulated by the nonconserved tyrosine 1316 in the insulin receptorShc and CEACAM1 interact to regulate the mitogenic action of insulinCEACAM1 modulates epidermal growth factor receptor--mediated cell proliferationThe carboxyl-terminal region of biliary glycoprotein controls its tyrosine phosphorylation and association with protein-tyrosine phosphatases SHP-1 and SHP-2 in epithelial cellsInsulin stimulates pp120 endocytosis in cells co-expressing insulin receptorsCarcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolismInsulin and insulin like growth factor II endocytosis and signaling via insulin receptor BInsulin-like growth factors in human breast cancer.Susceptibility to diet-induced hepatic steatosis and glucocorticoid resistance in FK506-binding protein 52-deficient mice.Caloric restriction reverses hepatic insulin resistance and steatosis in rats with low aerobic capacity.Extracellular IgC2 constant domains of CEACAMs mediate PI3K sensitivity during uptake of pathogens.A new highly efficient substrate-trapping mutant of protein tyrosine phosphatase 1B (PTP1B) reveals full autoactivation of the insulin receptor precursor.Mice with null mutation of Ceacam I develop nonalcoholic steatohepatitis.Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin ResistanceDifferential effects of prenatal stress on metabolic programming in diet-induced obese and dietary-resistant ratsIncreased Glucose-induced Secretion of Glucagon-like Peptide-1 in Mice Lacking the Carcinoembryonic Antigen-related Cell Adhesion Molecule 2 (CEACAM2).PPARα (Peroxisome Proliferator-activated Receptor α) Activation Reduces Hepatic CEACAM1 Protein Expression to Regulate Fatty Acid Oxidation during Fasting-refeeding Transition.CEACAM1 loss links inflammation to insulin resistance in obesity and non-alcoholic steatohepatitis (NASH).Inputs and outputs of insulin receptor.Reduced Hepatic Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Level in Obesity.Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis.The CEACAM1-L glycoprotein associates with the actin cytoskeleton and localizes to cell-cell contact through activation of Rho-like GTPases.Loss of Hepatic CEACAM1: A Unifying Mechanism Linking Insulin Resistance to Obesity and Non-Alcoholic Fatty Liver DiseaseCEACAM1 as a multi-purpose target for cancer immunotherapy.Comparison of the intracellular trafficking of two alternatively spliced isoforms of pp120, a substrate of the insulin receptor tyrosine kinase.The CEACAM1-L Ser503 residue is crucial for inhibition of colon cancer cell tumorigenicity.Cloning and characterization of a functional promoter of the rat pp120 gene, encoding a substrate of the insulin receptor tyrosine kinase.cis-Determinants in the cytoplasmic domain of CEACAM1 responsible for its tumor inhibitory function.Effect of pp120 on receptor-mediated insulin endocytosis is regulated by the juxtamembrane domain of the insulin receptor.Interaction between altered insulin and lipid metabolism in CEACAM1-inactive transgenic mice.Fenofibrate Decreases Insulin Clearance and Insulin Secretion to Maintain Insulin Sensitivity.Beta-cell "rest" accompanies reduced first-pass hepatic insulin extraction in the insulin-resistant, fat-fed canine model.Mechanism of glucose intolerance in mice with dominant negative mutation of CEACAM1.
P2860
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P2860
Receptor-mediated internalization of insulin. Potential role of pp120/HA4, a substrate of the insulin receptor kinase
description
1995 nî lūn-bûn
@nan
1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Receptor-mediated internalizat ...... of the insulin receptor kinase
@ast
Receptor-mediated internalizat ...... of the insulin receptor kinase
@en
Receptor-mediated internalizat ...... of the insulin receptor kinase
@nl
type
label
Receptor-mediated internalizat ...... of the insulin receptor kinase
@ast
Receptor-mediated internalizat ...... of the insulin receptor kinase
@en
Receptor-mediated internalizat ...... of the insulin receptor kinase
@nl
prefLabel
Receptor-mediated internalizat ...... of the insulin receptor kinase
@ast
Receptor-mediated internalizat ...... of the insulin receptor kinase
@en
Receptor-mediated internalizat ...... of the insulin receptor kinase
@nl
P2093
P2860
P356
P1476
Receptor-mediated internalizat ...... of the insulin receptor kinase
@en
P2093
C L Kern-Buell
N Philippe
P Formisano
S M Najjar
P2860
P304
P356
10.1074/JBC.270.41.24073
P407
P577
1995-10-13T00:00:00Z