Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop
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Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factorExome sequencing identifies truncating mutations in human SERPINF1 in autosomal-recessive osteogenesis imperfectaEffects of human recombinant PEDF protein and PEDF-derived peptide 34-mer on choroidal neovascularizationRecombinant human pigment epithelium-derived factor (PEDF): characterization of PEDF overexpressed and secreted by eukaryotic cellsGlycosaminoglycans in human retinoblastoma cells: heparan sulfate, a modulator of the pigment epithelium-derived factor-receptor interactionsPigment epithelium-derived factor: clinical significance in estrogen-dependent tissues and its potential in cancer therapyPEDF and its roles in physiological and pathological conditions: implication in diabetic and hypoxia-induced angiogenic diseasesNovel roles of kallistatin, a specific tissue kallikrein inhibitor, in vascular remodelingMaspin inhibits cell migration in the absence of protease inhibitory activityEvidence for a direct interaction between the tumor suppressor serpin, maspin, and types I and III collagenPigment epithelium-derived factor (PEDF) as a therapeutic target in cardiovascular diseaseCharacterization of PEDF: a multi-functional serpin family proteinKallikrein-binding protein inhibits retinal neovascularization and decreases vascular leakageSmall Retinoprotective Peptides Reveal a Receptor-binding Region on Pigment Epithelium-derived Factor.Unbalanced expression of VEGF and PEDF in ischemia-induced retinal neovascularization.Heparin binding induces a conformational change in pigment epithelium-derived factor.Pigment epithelium-derived factor protects retinal ganglion cells.Pigment epithelium-derived factor as an anticancer drug and new treatment methods following the discovery of its receptors: a patent perspective.Identification of the antivasopermeability effect of pigment epithelium-derived factor and its active site.Enhanced efficacy of combination therapy with adeno‑associated virus-delivered pigment epithelium-derived factor and cisplatin in a mouse model of Lewis lung carcinoma.Overexpression of pigment epithelium-derived factor inhibits retinal inflammation and neovascularization.Comparison of two neurotrophic serpins reveals a small fragment with cell survival activity.Identification of centerin: a novel human germinal center B cell-restricted serpin.Pigment epithelium-derived factor (PEDF) interacts with transportin SR2, and active nuclear import is facilitated by a novel nuclear localization motif.Common genetic variation in the SERPINF1 locus determines overall adiposity, obesity-related insulin resistance, and circulating leptin levels.AAV-mediated human PEDF inhibits tumor growth and metastasis in murine colorectal peritoneal carcinomatosis modelObesity as a risk and severity factor in rheumatic diseases (autoimmune chronic inflammatory diseases).Targeting Neovascularization in Ischemic Retinopathy: Recent AdvancesPigment epithelium-derived factor (PEDF), a serpin with potent anti-angiogenic and neurite outgrowth-promoting properties.Changes in the gene expression profile of A375 human melanoma cells induced by overexpression of multifunctional pigment epithelium-derived factorIdentification of a novel inhibitor of the canonical Wnt pathway.PEDF and PEDF-derived peptide 44mer stimulate cardiac triglyceride degradation via ATGL.Angiogenesis: a curse or cure?Pigment epithelium-derived factor (PEDF) protects cortical neurons in vitro from oxidant injury by activation of extracellular signal-regulated kinase (ERK) 1/2 and induction of Bcl-2.Gene Therapies for Neovascular Age-Related Macular Degeneration.Identification of pigment epithelium-derived factor protein forms with distinct activities on tumor cell lines.Pigment Epithelium-Derived Factor Mediates Autophagy and Apoptosis in Myocardial Hypoxia/Reoxygenation Injury.Alterations in protein regulators of neurodevelopment in the cerebrospinal fluid of infants with posthemorrhagic hydrocephalus of prematurity.Characterization of the human aqueous humour proteome: A comparison of the genders.Inhibition of tumor cell surface ATP synthesis by pigment epithelium-derived factor: implications for antitumor activity.
P2860
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P2860
Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop
description
1995 nî lūn-bûn
@nan
1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
name
Pigment epithelium-derived fac ...... quire the serpin reactive loop
@ast
Pigment epithelium-derived fac ...... quire the serpin reactive loop
@en
Pigment epithelium-derived fac ...... quire the serpin reactive loop
@nl
type
label
Pigment epithelium-derived fac ...... quire the serpin reactive loop
@ast
Pigment epithelium-derived fac ...... quire the serpin reactive loop
@en
Pigment epithelium-derived fac ...... quire the serpin reactive loop
@nl
prefLabel
Pigment epithelium-derived fac ...... quire the serpin reactive loop
@ast
Pigment epithelium-derived fac ...... quire the serpin reactive loop
@en
Pigment epithelium-derived fac ...... quire the serpin reactive loop
@nl
P2093
P3181
P356
P1476
Pigment epithelium-derived fac ...... quire the serpin reactive loop
@en
P2093
P Spinella
S P Becerra
P304
P3181
P356
10.1074/JBC.270.43.25992
P407
P577
1995-10-27T00:00:00Z