about
Plant and animal pathogen recognition receptors signal through non-RD kinasesIdentification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteinsPBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21TOPK promotes lung cancer resistance to EGFR tyrosine kinase inhibitors by phosphorylating and activating c-JunT-LAK cell-originated protein kinase (TOPK) phosphorylation of MKP1 protein prevents solar ultraviolet light-induced inflammation through inhibition of the p38 protein signaling pathwayConvergent and divergent ligand specificity among PDZ domains of the LAP and zonula occludens (ZO) families.The T-LAK Cell-originated Protein Kinase Signal Pathway Promotes Colorectal Cancer Metastasis.Prognostic and predictive value of TOPK stratified by KRAS and BRAF gene alterations in sporadic, hereditary and metastatic colorectal cancer patients.PI3K/Akt-sensitive MEK-independent compensatory circuit of ERK activation in ER-positive PI3K-mutant T47D breast cancer cellsT-LAK cell-originated protein kinase (TOPK) phosphorylation of Prx1 at Ser-32 prevents UVB-induced apoptosis in RPMI7951 melanoma cells through the regulation of Prx1 peroxidase activity.Expression of PBK/TOPK in cervical cancer and cervical intraepithelial neoplasia.Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivoLymphokine-activated killer T-cell-originated protein kinase phosphorylation of histone H2AX prevents arsenite-induced apoptosis in RPMI7951 melanoma cells.Phosphorylation of TOPK at Y74, Y272 by Src increases the stability of TOPK and promotes tumorigenesis of colonCefradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of T-LAK cell-originated protein kinase.PDZ binding kinase (PBK) is a theranostic target for nasopharyngeal carcinoma: driving tumor growth via ROS signaling and correlating with patient survivalT-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia.PBK/TOPK enhances aggressive phenotype in prostate cancer via β-catenin-TCF/LEF-mediated matrix metalloproteinases production and invasion.Overexpression of PBK/TOPK relates to tumour malignant potential and poor outcome of gastric carcinoma.Proton pump inhibitor ilaprazole suppresses cancer growth by targeting T-cell-originated protein kinaseTOPK/PBK promotes cell migration via modulation of the PI3K/PTEN/AKT pathway and is associated with poor prognosis in lung cancer.Dissection of a complex transcriptional response using genome-wide transcriptional modelling.PBK/TOPK promotes tumour cell proliferation through p38 MAPK activity and regulation of the DNA damage response.Expression and phosphorylation of TOPK during spermatogenesis.Ginsenoside Rh2 inhibiting HCT116 colon cancer cell proliferation through blocking PDZ-binding kinase/T-LAK cell-originated protein kinase.TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapyActivation of T-LAK-cell-originated protein kinase-mediated antioxidation protects against focal cerebral ischemia-reperfusion injury.Enhanced Expression of the Key Mitosis Regulator Cyclin B1 Is Mediated by PDZ-Binding Kinase in Islets of Pregnant Mice.In silico structural and functional analysis of the human TOPK protein by structure modeling and molecular dynamics studies.TOPK Promotes Microglia/Macrophage Polarization towards M2 Phenotype via Inhibition of HDAC1 and HDAC2 Activity after Transient Cerebral Ischemia.
P2860
Q21131622-85E64FA6-375F-445B-9250-5D0746516610Q24313384-065272B3-E33F-4A87-8629-3B8B91CBDCFAQ24338602-4764E8FE-25CE-423A-AC1C-0E46394A39E0Q27853317-05B4A2E4-A03F-41A1-82D4-BD68E6CDACE9Q28513822-CFE323F8-E89C-4903-85CC-0F14F93BF216Q33245309-DF149492-71FC-49CE-A514-C55F81139C39Q33603725-A62ED47C-C125-4159-82C4-410B0A93C359Q33620070-A668EDE6-5B8B-488D-883C-4A37B69BA6E4Q33945648-73781EA3-F7BC-411D-8EDB-557EB70F34BFQ34121493-56DF34A0-CEF2-4EE2-80A6-0B702074864AQ34732849-3FBB05B0-85C6-4240-87B4-B4A03A54F5DAQ35750188-875BCC6E-91CF-4128-B3E3-191A213EE051Q36453943-EDAD55EA-F921-43BE-8E70-5226A27FB0E3Q37269345-005B35F0-E865-4DBC-A08F-AE9DEF2BF664Q37269385-3CAC6461-83C5-4BD7-8A3A-3F0AB3178EBBQ37295736-C418D635-62D4-4547-8D2C-D4E887C8200CQ38261327-33DF47E1-6789-4D24-B0AC-0E80C6FFAAA8Q38386707-F6FFABBC-5C65-4493-B550-1C9DDD399A02Q38728416-7322326B-A1CE-4AC2-A7C8-51C69420D526Q38847726-22A20F7C-0605-45E2-A16E-90DA8FCAAE95Q39458588-AE087CA3-2BB7-4A2F-93AC-1800FAB71E18Q39773509-F5C216CF-EAC7-49B2-A173-1464241C8765Q40198127-2C1A381E-51F0-420B-8FD9-43B80EC39AFFQ40346207-0175166A-6C42-44C0-AFFC-542C106A3452Q41342625-DDD30297-BF14-4943-B2EE-10EEF8B384D1Q41431230-56E3DEBD-D439-454C-AEC6-B993DE987532Q42704688-31474D04-4256-4D04-A7BC-1CB02341CBDFQ54118809-8C6EB5B6-58D2-493C-80F4-26A84ACFE6F8Q54486640-FDE0DB64-C35F-4DDD-AB34-97D024D1675AQ55040197-2C8C9E0D-1B3B-464C-ACE5-99F78F5333CD
P2860
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Characterization of a MAPKK-like protein kinase TOPK
@ast
Characterization of a MAPKK-like protein kinase TOPK
@en
Characterization of a MAPKK-like protein kinase TOPK
@nl
type
label
Characterization of a MAPKK-like protein kinase TOPK
@ast
Characterization of a MAPKK-like protein kinase TOPK
@en
Characterization of a MAPKK-like protein kinase TOPK
@nl
prefLabel
Characterization of a MAPKK-like protein kinase TOPK
@ast
Characterization of a MAPKK-like protein kinase TOPK
@en
Characterization of a MAPKK-like protein kinase TOPK
@nl
P2093
P3181
P1476
Characterization of a MAPKK-like protein kinase TOPK
@en
P2093
Katsumi Kito
Kazuhiro Shigemoto
Kiyofumi Gyo
Norifumi Ueda
Suguru Matsumoto
Takashi Takeuchi
Taketsugu Fujibuchi
Yasuhito Abe
P304
P3181
P356
10.1016/J.BBRC.2004.10.133
P407
P577
2004-12-17T00:00:00Z