Reduction in hepatic drug metabolizing CYP3A4 activities caused by P450 oxidoreductase mutations identified in patients with disordered steroid metabolism
about
Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiencyPharmacogenomics of human P450 oxidoreductaseInfluence of various polymorphic variants of cytochrome P450 oxidoreductase (POR) on drug metabolic activity of CYP3A4 and CYP2B6Role of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicityIdentification of six novel P450 oxidoreductase missense variants in Ashkenazi and Moroccan Jewish populations.Identification of cytochrome P450 oxidoreductase gene variants that are significantly associated with the interindividual variations in warfarin maintenance dose.Altered human CYP3A4 activity caused by Antley-Bixler syndrome-related variants of NADPH-cytochrome P450 oxidoreductase measured in a robust in vitro systemConsequences of POR mutations and polymorphisms.Genetic variations in NADPH-CYP450 oxidoreductase in a Czech Slavic cohort.NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology.Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" ProblemCytochrome P450 oxidoreductase deficiency caused by R457H mutation in POR gene in Chinese: case report and literature review.Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype.Altered CYP19A1 and CYP3A4 Activities Due to Mutations A115V, T142A, Q153R and P284L in the Human P450 Oxidoreductase.Octahydropyrrolo[3,4-c]pyrrole negative allosteric modulators of mGlu1.Discovery of VU0409106: A negative allosteric modulator of mGlu5 with activity in a mouse model of anxietyEffect of the P450 oxidoreductase 28 polymorphism on the pharmacokinetics of tacrolimus in Chinese healthy male volunteers.Editorial: Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function.Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency.
P2860
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P2860
Reduction in hepatic drug metabolizing CYP3A4 activities caused by P450 oxidoreductase mutations identified in patients with disordered steroid metabolism
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Reduction in hepatic drug meta ...... disordered steroid metabolism
@ast
Reduction in hepatic drug meta ...... disordered steroid metabolism
@en
Reduction in hepatic drug meta ...... disordered steroid metabolism
@nl
type
label
Reduction in hepatic drug meta ...... disordered steroid metabolism
@ast
Reduction in hepatic drug meta ...... disordered steroid metabolism
@en
Reduction in hepatic drug meta ...... disordered steroid metabolism
@nl
prefLabel
Reduction in hepatic drug meta ...... disordered steroid metabolism
@ast
Reduction in hepatic drug meta ...... disordered steroid metabolism
@en
Reduction in hepatic drug meta ...... disordered steroid metabolism
@nl
P1476
Reduction in hepatic drug meta ...... disordered steroid metabolism
@en
P2093
Christa E Flück
Primus E Mullis
P304
P356
10.1016/J.BBRC.2010.09.035
P407
P577
2010-10-08T00:00:00Z