NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity
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P1343
A potential mechanism underlying the increased susceptibility of individuals with a polymorphism in NAD(P)H:quinone oxidoreductase 1 (NQO1) to benzene toxicityCollapse of the native structure caused by a single amino acid exchange in human NAD(P)H:quinone oxidoreductase(1.)Association of genetic polymorphisms in CYP2E1, MPO, NQO1, GSTM1, and GSTT1 genes with benzene poisoning.Implications of NQO1 in cancer therapyNAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinonesA novel strategy for NQO1 (NAD(P)H:quinone oxidoreductase, EC 1.6.99.2) mediated therapy of bladder cancer based on the pharmacological properties of EO9Induction of phase 2 antioxidant enzymes by broccoli sulforaphane: perspectives in maintaining the antioxidant activity of vitamins a, C, and ePolymorphisms of xenobiotic-metabolizing enzymes and susceptibility to cancerUse of NQO1 status as a selective biomarker for oesophageal squamous cell carcinomas with greater sensitivity to 17-AAGBenzene, NQO1, and genetic susceptibility to cancer.Association of human NAD(P)H:quinone oxidoreductase 1 (NQO1) polymorphism with development of acute lung injury.Relationships between metabolic and non-metabolic susceptibility factors in benzene toxicity.Molecular emergence of acute myeloid leukemia during treatment for acute lymphoblastic leukemiaA functional NQO1 609C>T polymorphism and risk of gastrointestinal cancers: a meta-analysis.P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1NQO1 C609T polymorphism and esophageal cancer risk: a HuGE review and meta-analysis.Role for NAD(P)H:quinone oxidoreductase 1 and manganese-dependent superoxide dismutase in 17-(allylamino)-17-demethoxygeldanamycin-induced heat shock protein 90 inhibition in pancreatic cancer cells.Interactive effect of smoking and NQO1 haplotypes on lung cancer risk.The NQO1*2/*2 polymorphism is associated with poor overall survival in patients following resection of stages II and IIIa non-small cell lung cancer.Mitomycin resistance in mammalian cells expressing the bacterial mitomycin C resistance protein MCRARole of NAD(P)H:quinone oxidoreductase 1 in clofibrate-mediated hepatoprotection from acetaminophen.Chemotherapy-induced toxicity is highly heritable in Drosophila melanogasterHigher activity of polymorphic NAD(P)H:quinone oxidoreductase in liver cytosols from blacks compared to whites.Presence of a heterozygous substitution and its relationship to DT-diaphorase activity.Transfection of COS-1 cells with DT-diaphorase cDNA: role of a base change at position 609Induction of DT-diaphorase by 1,2-dithiole-3-thiones in human tumour and normal cells and effect on anti-tumour activity of bioreductive agents.NAD(P)H:quinone oxidoreductase 1 protects bladder epithelium against painful bladder syndrome in mice.Characterization of a polymorphism in NAD(P)H: quinone oxidoreductase (DT-diaphorase).Ethnic variation in the prevalence of a common NAD(P)H quinone oxidoreductase polymorphism and its implications for anti-cancer chemotherapy.NAD(P)H:quinone oxidoreductase 1 (NQO1) competes with 20S proteasome for binding with C/EBPα leading to its stabilization and protection against radiation-induced myeloproliferative disease.Assessment of the relationship between genotypic status of a DT-diaphorase point mutation and enzymatic activityC609T Polymorphism of NADPH Quinone Oxidoreductase 1 Correlates Clinical Hematological Toxicities in Lung Cancer Patients Treated with Amrubicin.GSTM1, GSTP1, and NQO1 polymorphisms and susceptibility to atopy and airway hyperresponsiveness among South African schoolchildren.Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to radiation-induced myeloproliferative disease.Calcium and calcium sensing receptor modulates the expression of thymidylate synthase, NAD(P)H:quinone oxidoreductase 1 and survivin in human colon carcinoma cells: promotion of cytotoxic response to mitomycin C and fluorouracil.NQO1 polymorphisms and de novo childhood leukemia: a HuGE review and meta-analysis.CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese populationStress-induced NQO1 controls stability of C/EBPα against 20S proteasomal degradation to regulate p63 expression with implications in protection against chemical-induced skin cancer.Preclinical efficacy of the bioreductive alkylating agent RH1 against paediatric tumours.The two common polymorphic forms of human NRH-quinone oxidoreductase 2 (NQO2) have different biochemical properties.
P2860
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P2860
NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity
description
1992 nî lūn-bûn
@nan
1992 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
name
NAD(P)H:quinone oxidoreductase ...... vity and mitomycin sensitivity
@ast
NAD(P)H:quinone oxidoreductase ...... vity and mitomycin sensitivity
@en
NAD(P)H:quinone oxidoreductase ...... vity and mitomycin sensitivity
@nl
type
label
NAD(P)H:quinone oxidoreductase ...... vity and mitomycin sensitivity
@ast
NAD(P)H:quinone oxidoreductase ...... vity and mitomycin sensitivity
@en
NAD(P)H:quinone oxidoreductase ...... vity and mitomycin sensitivity
@nl
prefLabel
NAD(P)H:quinone oxidoreductase ...... vity and mitomycin sensitivity
@ast
NAD(P)H:quinone oxidoreductase ...... vity and mitomycin sensitivity
@en
NAD(P)H:quinone oxidoreductase ...... vity and mitomycin sensitivity
@nl
P2093
P1433
P1476
NAD(P)H:quinone oxidoreductase ...... vity and mitomycin sensitivity
@en
P2093
K D Danenberg
N W Gibson
P V Danenberg
R D Traver
T H Stadlbauer
T Horikoshi
P304
P407
P4510
P577
1992-02-15T00:00:00Z