A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems
about
Glycopeptide-preferring polypeptide GalNAc transferase 10 (ppGalNAc T10), involved in mucin-type O-glycosylation, has a unique GalNAc-O-Ser/Thr-binding site in its catalytic domain not found in ppGalNAc T1 or T2Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynonesSynthesis of a fluorogenic cyclooctyne activated by Cu-free click chemistryCu-free click cycloaddition reactions in chemical biologyBioorthogonal chemistry: fishing for selectivity in a sea of functionalityA bioorthogonal quadricyclane ligationTetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivityA hydrophilic azacyclooctyne for Cu-free click chemistryImaging cell surface glycans with bioorthogonal chemical reportersCrosslinking studies of protein-protein interactions in nonribosomal peptide biosynthesisSelective labeling of living cells by a photo-triggered click reactionCopper-free click chemistry for dynamic in vivo imagingClick Chemistry-Mediated Nanosensors for Biochemical Assays25th anniversary article: Rational design and applications of hydrogels in regenerative medicineClick chemistry in complex mixtures: bioorthogonal bioconjugationAn unexpected journey: lysine methylation across the proteomeAlkyne-azide "click" chemistry in designing nanocarriers for applications in biologySpecific and quantitative labeling of biomolecules using click chemistryBioorthogonal chemistry: strategies and recent developmentsDouble Strain-Promoted Macrocyclization for the Rapid Selection of Cell-Active Stapled PeptidesRecent advances in covalent, site-specific protein immobilizationDevelopment and Applications of the Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) as a Bioorthogonal ReactionModular and orthogonal synthesis of hybrid polymers and networksChoosing an effective protein bioconjugation strategyAdvances in BioconjugationMetabolic labeling of Caenorhabditis elegans primary embryonic cells with azido-sugars as a tool for glycoprotein discoveryNovel modifications in RNADiazo Compounds: Versatile Tools for Chemical BiologyDecreasing Distortion Energies without Strain: Diazo-Selective 1,3-Dipolar Cycloadditions1,3-Dipolar Cycloadditions of Diazo Compounds in the Presence of AzidesIncorporation of non-canonical amino acids into the developing murine proteomeSuper-Resolution Imaging of Plasma Membrane Proteins with Click ChemistryPhoto-Triggered Click Chemistry for Biological ApplicationsΠ-Clamp-mediated cysteine conjugationClick-EM for imaging metabolically tagged nonprotein biomoleculesAmphiphilic peptides and their cross-disciplinary role as building blocks for nanoscienceControlled Orientation of Active Sites in a Nanostructured Multienzyme Complex.Bioconjugation of therapeutic proteins and enzymes using the expanded set of genetically encoded amino acids.Site-specific albumination of a therapeutic protein with multi-subunit to prolong activity in vivoPerspective: A toolbox for protein structure determination in physiological environment through oriented, 2D ordered, site specific immobilization.
P2860
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P2860
A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年學術文章
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name
A strain-promoted [3 + 2] azid ...... biomolecules in living systems
@ast
A strain-promoted [3 + 2] azid ...... biomolecules in living systems
@en
A strain-promoted [3 + 2] azid ...... biomolecules in living systems
@nl
type
label
A strain-promoted [3 + 2] azid ...... biomolecules in living systems
@ast
A strain-promoted [3 + 2] azid ...... biomolecules in living systems
@en
A strain-promoted [3 + 2] azid ...... biomolecules in living systems
@nl
prefLabel
A strain-promoted [3 + 2] azid ...... biomolecules in living systems
@ast
A strain-promoted [3 + 2] azid ...... biomolecules in living systems
@en
A strain-promoted [3 + 2] azid ...... biomolecules in living systems
@nl
P3181
P356
P1476
A strain-promoted [3 + 2] azid ...... biomolecules in living systems
@en
P2093
Nicholas J Agard
P304
P3181
P356
10.1021/JA044996F
P407
P577
2004-11-24T00:00:00Z