An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
about
REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasisProtein prenyltransferasesACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterizationPeroxisome proliferator-activated receptor alpha-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosiscDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolismcDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brainRole of LXRs in control of lipogenesisCharacterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the proteinNPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterolsStructural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgammaActivation of LXR increases acyl-CoA synthetase activity through direct regulation of ACSL3 in human placental trophoblast cellsRegulation of ALK-1 signaling by the nuclear receptor LXRbetaActivation of the nuclear receptor LXR by oxysterols defines a new hormone response pathwayActivation of the orphan receptor RIP14 by retinoidsSynthetic LXR ligand inhibits the development of atherosclerosis in micePolyunsaturated fatty acids decrease the expression of sterol regulatory element-binding protein-1 in CaCo-2 cells: effect on fatty acid synthesis and triacylglycerol transportPotentiation of liver X receptor transcriptional activity by peroxisome-proliferator-activated receptor gamma co-activator 1 alphaLiver X receptors in the central nervous system: from lipid homeostasis to neuronal degenerationThe hypocholesterolemic agent LY295427 up-regulates INSIG-1, identifying the INSIG-1 protein as a mediator of cholesterol homeostasis through SREBPIdentification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterolOxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport proteinLXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytesIdentification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoterDo oxysterols control cholesterol homeostasis?Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbetaAn oxysterol biomarker for 7-dehydrocholesterol oxidation in cell/mouse models for Smith-Lemli-Opitz syndromeRegulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbetaLiver x receptors in atherosclerosis and inflammationLipid biomarkers of oxidative stress in a genetic mouse model of Smith-Lemli-Opitz syndromeRegulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responsesPPARgamma1 and LXRalpha face a new regulator of macrophage cholesterol homeostasis and inflammatory responsiveness, AEBP1Identification of a human nuclear receptor defines a new signaling pathway for CYP3A inductionThe pathogenesis of Niemann-Pick type C disease: a role for autophagy?Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in miceCPF: an orphan nuclear receptor that regulates liver-specific expression of the human cholesterol 7alpha-hydroxylase geneSynthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemiaThe orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolismBile acids: regulation of synthesisPregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C diseaseIn vitro and in vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism
P2860
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P2860
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
description
1996 nî lūn-bûn
@nan
1996 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
@ast
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
@en
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
@nl
type
label
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
@ast
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
@en
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
@nl
prefLabel
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
@ast
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
@en
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
@nl
P2093
P3181
P356
P1433
P1476
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
@en
P2093
B A Janowski
D J Mangelsdorf
P2888
P304
P3181
P356
10.1038/383728A0
P407
P577
1996-10-24T00:00:00Z
P6179
1023775165