Interaction of focal adhesion kinase with cytoskeletal protein talin
about
Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane rufflesConformation, localization, and integrin binding of talin depend on its interaction with phosphoinositidesAssociation of Grb7 with phosphoinositides and its role in the regulation of cell migrationFAK promotes recruitment of talin to nascent adhesions to control cell motilityCell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesionsIdentification of p130Cas as a mediator of focal adhesion kinase-promoted cell migrationEvidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinasesRegulation of focal adhesion kinase by a novel protein inhibitor FIP200The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assemblyFocal adhesion kinase and p130Cas mediate both sarcomeric organization and activation of genes associated with cardiac myocyte hypertrophyActivation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundleAn SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinaseJanus kinases and focal adhesion kinases play in the 4.1 band: a superfamily of band 4.1 domains important for cell structure and signal transductionThe integrin-actin connection, an eternal love affairSuppression of Pyk2 kinase and cellular activities by FIP200Altering FAK-paxillin interactions reduces adhesion, migration and invasion processesNudel and FAK as antagonizing strength modulators of nascent adhesions through paxillinStructural insight into the mechanisms of targeting and signaling of focal adhesion kinase.NMR solution structure of the focal adhesion targeting domain of focal adhesion kinase in complex with a paxillin LD peptide: evidence for a two-site binding modelAlternative splicing controls the mechanisms of FAK autophosphorylationAssociation of focal adhesion kinase with Grb7 and its role in cell migrationFocal adhesion kinase activates Stat1 in integrin-mediated cell migration and adhesionFocal adhesion kinase in netrin-1 signalingThe role of conserved amino acid motifs within the integrin beta3 cytoplasmic domain in triggering focal adhesion kinase phosphorylationSrc mediates stimulation by vascular endothelial growth factor of the phosphorylation of focal adhesion kinase at tyrosine 861, and migration and anti-apoptosis in endothelial cellsEpidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinaseThe headpiece domain of dematin regulates cell shape, motility, and wound healing by modulating RhoA activationMultiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation eventsCleavage of focal adhesion kinase by caspases during apoptosisBiophysical properties of intrinsically disordered p130Cas substrate domain--implication in mechanosensingForce Sensing by Mechanical Extension of the Src Family Kinase Substrate p130CasVinculin-p130Cas interaction is critical for focal adhesion dynamics and mechano-transduction.SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading.Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs.Regulation of focal adhesion targeting and inhibitory functions of the FAK related protein FRNK using a novel estrogen receptor "switch".Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells.Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cellsDegraded collagen fragments promote rapid disassembly of smooth muscle focal adhesions that correlates with cleavage of pp125(FAK), paxillin, and talinInduction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase.Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation.
P2860
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P2860
Interaction of focal adhesion kinase with cytoskeletal protein talin
description
1995 nî lūn-bûn
@nan
1995 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Interaction of focal adhesion kinase with cytoskeletal protein talin
@ast
Interaction of focal adhesion kinase with cytoskeletal protein talin
@en
Interaction of focal adhesion kinase with cytoskeletal protein talin
@nl
type
label
Interaction of focal adhesion kinase with cytoskeletal protein talin
@ast
Interaction of focal adhesion kinase with cytoskeletal protein talin
@en
Interaction of focal adhesion kinase with cytoskeletal protein talin
@nl
prefLabel
Interaction of focal adhesion kinase with cytoskeletal protein talin
@ast
Interaction of focal adhesion kinase with cytoskeletal protein talin
@en
Interaction of focal adhesion kinase with cytoskeletal protein talin
@nl
P2093
P2860
P3181
P356
P1476
Interaction of focal adhesion kinase with cytoskeletal protein talin
@en
P2093
J D Hildebrand
J T Parsons
M D Schaller
P A Appeddu
P2860
P304
P3181
P356
10.1074/JBC.270.28.16995
P407
P577
1995-07-14T00:00:00Z