Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro - Wikidata - awgldk - TriplyDB

Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

http://www.wikidata.org/entity/Q28295439

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The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders Pharmacogenomics of human P450 oxidoreductase Pharmacogenomics of Drug Metabolizing Enzymes and Transporters: Relevance to Precision Medicine Influence of various polymorphic variants of cytochrome P450 oxidoreductase (POR) on drug metabolic activity of CYP3A4 and CYP2B6 Cytochrome P450 Oxidoreductase Influences CYP2B6 Activity in Cyclophosphamide Bioactivation Role of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicity Pharmacogenetics in Jewish populations.Identification of six novel P450 oxidoreductase missense variants in Ashkenazi and Moroccan Jewish populations.High-yield expression of a catalytically active membrane-bound protein: human P450 oxidoreductase.Identification of cytochrome P450 oxidoreductase gene variants that are significantly associated with the interindividual variations in warfarin maintenance dose.Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5.Altered human CYP3A4 activity caused by Antley-Bixler syndrome-related variants of NADPH-cytochrome P450 oxidoreductase measured in a robust in vitro system Multigene predictors of tacrolimus exposure in kidney transplant recipients.Consequences of POR mutations and polymorphisms.Genetic variations in NADPH-CYP450 oxidoreductase in a Czech Slavic cohort.Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children.Prediction of CYP2D6 phenotype from genotype across world populations Cytochrome P450 oxidoreductase deficiency caused by R457H mutation in POR gene in Chinese: case report and literature review.Influence of genetic polymorphisms in cytochrome P450 oxidoreductase on the variability in stable warfarin maintenance dose in Han Chinese.Associations of cytochrome P450 oxidoreductase genetic polymorphisms with smoking cessation in a Chinese population.Electron transfer by human wild-type and A287P mutant P450 oxidoreductase assessed by transient kinetics: functional basis of P450 oxidoreductase deficiency.Coexpression of CPR from various origins enhances biotransformation activity of human CYPs in S. pombe.Cytochrome P450 oxidoreductase genetic polymorphisms A503V and rs2868177 do not significantly affect warfarin stable dosage in Han-Chinese patients with mechanical heart valve replacement.In vitro fertilization-frozen embryo transfer in a patient with cytochrome P450 oxidoreductase deficiency: a case report.The P450 oxidoreductase (POR) rs2868177 and cytochrome P450 (CYP) 2B6*6 polymorphisms contribute to the interindividual variability in human CYP2B6 activity.POR*28 SNP is associated with lipid response to atorvastatin in children and adolescents with familial hypercholesterolemia.Genetic Polymorphisms and In Silico Mutagenesis Analyses of CYP2C9, CYP2D6, and CYPOR Genes in the Pakistani Population

P2860

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P2860

Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

http://www.wikidata.org/entity/Q28295439

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

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Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

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Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

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type

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Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

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Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

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Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

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prefLabel

Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

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Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

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Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

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Pharmacogenetics and Genomics

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Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro

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Duanpen Sandee

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Harrison K Tam

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Kari Morrissey

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Kathleen M Giacomini

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Melissa A Kramer

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Timothy S Tracy

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Walter L Miller

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P2860

Diversity and function of mutations in p450 oxidoreductase in patients with Antley-Bixler syndrome and disordered steroidogenesis

Substrate-specific modulation of CYP3A4 activity by genetic variants of cytochrome P450 oxidoreductase

Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes

NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer

Liver-specific deletion of the NADPH-cytochrome P450 reductase gene: impact on plasma cholesterol homeostasis and the function and regulation of microsomal cytochrome P450 and heme oxygenase

Association of multiple developmental defects and embryonic lethality with loss of microsomal NADPH-cytochrome P450 oxidoreductase

Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome

Restoration of mutant cytochrome P450 reductase activity by external flavin

Modulation of human CYP19A1 activity by mutant NADPH P450 oxidoreductase

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

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