The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity
about
Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell deathp58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacityFANCC interacts with Hsp70 to protect hematopoietic cells from IFN-gamma/TNF-alpha-mediated cytotoxicity.Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.Antiviral actions of interferonsCrystal Structure of P58(IPK) TPR Fragment Reveals the Mechanism for its Molecular Chaperone Activity in UPRFunctions of the influenza A virus NS1 protein in antiviral defenseA mouse homologue of the Drosophila tumor suppressor l(2)tid gene defines a novel Ras GTPase-activating protein (RasGAP)-binding proteinDeath-associated protein 4 binds MST1 and augments MST1-induced apoptosisThe anti-apoptotic function of Hsp70 in the interferon-inducible double-stranded RNA-dependent protein kinase-mediated death signaling pathway requires the Fanconi anemia protein, FANCCXBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein responseInfluenza virus NS1 protein counteracts PKR-mediated inhibition of replication.Fanconi anemia proteins and their interacting partners: a molecular puzzleAndes virus nucleocapsid protein interrupts protein kinase R dimerization to counteract host interference in viral protein synthesis.Innate immune evasion strategies of influenza virusesTranslational control of viral gene expression in eukaryotesInhibition of double-stranded RNA- and tumor necrosis factor alpha-mediated apoptosis by tetratricopeptide repeat protein and cochaperone P58(IPK)Dual role for Hsc70 in the biogenesis and regulation of the heme-regulated kinase of the alpha subunit of eukaryotic translation initiation factor 2Molecular pathways in virus-induced cytokine production.Tipping the balance: antagonism of PKR kinase and ADAR1 deaminase functions by virus gene products.Viruses, endoplasmic reticulum stress, and interferon responses.The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-mediated mechanismProteomic analysis of Frankliniella occidentalis and differentially expressed proteins in response to tomato spotted wilt virus infection.Robust expression of vault RNAs induced by influenza A virus plays a critical role in suppression of PKR-mediated innate immunity.Regulation of eukaryotic protein synthesis: selective influenza viral mRNA translation is mediated by the cellular RNA-binding protein GRSF-1.Viral persistence and chronic immunopathology in the adult central nervous system following Coxsackievirus infection during the neonatal period.Viral tricks to grid-lock the type I interferon system.Influenza virus and cell signaling pathways.Induction and evasion of type I interferon responses by influenza viruses.Preliminary X-ray crystallographic studies of mouse UPR responsive protein P58(IPK) TPR fragment.Continuous cell lines from the Muscovy duck as potential replacement for primary cells in the production of avian vaccines.Inhibition of protein kinase R activation and upregulation of GADD34 expression play a synergistic role in facilitating coronavirus replication by maintaining de novo protein synthesis in virus-infected cells.ADAR1 interacts with PKR during human immunodeficiency virus infection of lymphocytes and contributes to viral replicationPersistent borna disease virus infection confers instability of HSP70 mRNA in glial cells during heat stress.Host proteostasis modulates influenza evolution.Role of nuclear factor-kappaB in the antiviral action of interferon and interferon-regulated gene expression.HSP40s activate intrinsic ATPase activity of HSP70s in the cytosolDNAJ Proteins in neurodegeneration: essential and protective factors.Double-stranded RNA-dependent protein kinase (pkr) is essential for thermotolerance, accumulation of HSP70, and stabilization of ARE-containing HSP70 mRNA during stress.
P2860
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P2860
The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The cellular inhibitor of the ...... heat shock protein 70 activity
@ast
The cellular inhibitor of the ...... heat shock protein 70 activity
@en
The cellular inhibitor of the ...... heat shock protein 70 activity
@nl
type
label
The cellular inhibitor of the ...... heat shock protein 70 activity
@ast
The cellular inhibitor of the ...... heat shock protein 70 activity
@en
The cellular inhibitor of the ...... heat shock protein 70 activity
@nl
prefLabel
The cellular inhibitor of the ...... heat shock protein 70 activity
@ast
The cellular inhibitor of the ...... heat shock protein 70 activity
@en
The cellular inhibitor of the ...... heat shock protein 70 activity
@nl
P2093
P2860
P356
P1476
The cellular inhibitor of the ...... heat shock protein 70 activity
@en
P2093
P2860
P304
P356
10.1074/JBC.274.6.3797
P407
P577
1999-02-05T00:00:00Z