A novel calpain inhibitor, ((1S)-1((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl) carbamic acid 5-methoxy-3-oxapentyl ester, protects neuronal cells from cerebral ischemia-induced damage in mice

A novel calpain inhibitor, ((1S)-1((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl) carbamic acid 5-methoxy-3-oxapentyl ester, protects neuronal cells from cerebral ischemia-induced damage in mice

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http://www.wikidata.org/entity/Q28296038

Q28296038

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Role of NMDA Receptor-Mediated Glutamatergic Signaling in Chronic and Acute Neuropathologies CDK5 knockdown prevents hippocampal degeneration and cognitive dysfunction produced by cerebral ischemia Involvement of calpains in adult neurogenesis: implications for stroke.Post-natal treatment by a blood-brain-barrier permeable calpain inhibitor, SNJ1945 rescued defective function in lissencephaly.SNJ-1945, a calpain inhibitor, protects SH-SY5Y cells against MPP(+) and rotenone.Cell death Visualizing cell death in experimental focal cerebral ischemia: promises, problems, and perspectives.Peptidyl alpha-ketoamides with nucleobases, methylpiperazine, and dimethylaminoalkyl substituents as calpain inhibitors Dual vulnerability of tau to calpains and caspase-3 proteolysis under neurotoxic and neurodegenerative conditions.Targeting p35/Cdk5 signalling via CIP-peptide promotes angiogenesis in hypoxia Degradation of βII-Spectrin Protein by Calpain-2 and Caspase-3 Under Neurotoxic and Traumatic Brain Injury Conditions Calpain, not caspase, is the causative protease for hypoxic damage in cultured monkey retinal cells.Method parameters' impact on mortality and variability in mouse stroke experiments: a meta-analysis.Inhibition of Histone Deacetylase 3 (HDAC3) Mediates Ischemic Preconditioning and Protects Cortical Neurons against Ischemia in Rats Control of photoreceptor autophagy after retinal detachment: the switch from survival to death.Multimodal neuroprotection induced by PACAP38 in oxygen-glucose deprivation and middle cerebral artery occlusion stroke models Delayed, oral pharmacological inhibition of calpains attenuates adverse post-infarction remodelling.Treatment of acute cerebral ischemia using animal models: a meta-analysis.Calpain-Dependent ErbB4 Cleavage Is Involved in Brain Ischemia-Induced Neuronal Death.Calpastatin overexpression limits calpain-mediated proteolysis and behavioral deficits following traumatic brain injury.A cardioprotective agent of a novel calpain inhibitor, SNJ-1945, exerts beta1 actions on left ventricular mechanical work and energetics.Cardioprotective effects of a novel calpain inhibitor SNJ-1945 for reperfusion injury after cardioplegic cardiac arrest.Pharmacological analysis of the cortical neuronal cytoskeletal protective efficacy of the calpain inhibitor SNJ-1945 in a mouse traumatic brain injury model.Calpain-2 as a therapeutic target for acute neuronal injury.Targeting calpain-mediated proteolysis and peptide signaling as a strategy to reduce injury in multiple sclerosis.Targeting NMDA receptors in stroke: new hope in neuroprotection.

P2860

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P2860

A novel calpain inhibitor, ((1S)-1((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl) carbamic acid 5-methoxy-3-oxapentyl ester, protects neuronal cells from cerebral ischemia-induced damage in mice

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http://www.wikidata.org/entity/Q28296038

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2008 nî lūn-bûn

@nan

2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

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