A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma - Wikidata - awgldk - TriplyDB

A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

http://www.wikidata.org/entity/Q28296086

about

RNA vaccines in cancer treatment Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding.CDK4 and CDK6 delay senescence by kinase-dependent and p16INK4a-independent mechanisms A proteome-scale map of the human interactome network Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformation The response of autologous T cells to a human melanoma is dominated by mutated neoantigens Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence.Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors Requirement of Cdk4 for v-Ha-ras-Induced Breast Tumorigenesis and Activation of the v-ras-Induced Senescence Program by the R24C Mutation Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes Crystal structure of human CDK4 in complex with a D-type cyclin Human tumor antigens recognized by T lymphocytes Tumor antigens for cancer immunotherapy: therapeutic potential of xenogeneic DNA vaccines Towards a Better Understanding of the Molecular Mechanisms Involved in Sunlight-Induced Melanoma T cell avidity and tumor recognition: implications and therapeutic strategies.Neoantigen-based cancer immunotherapy Safety of targeting tumor endothelial cell antigens Targeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitors Peptide-based vaccines for cancer therapy Melanoma: from mutations to medicine Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice Structure of the cyclin-dependent kinase inhibitor p19Ink4d A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast.The INK4 family of cell cycle inhibitors in cancer cdk6 can shorten G(1) phase dependent upon the N-terminal INK4 interaction domain Tumor-associated antigens as possible targets for immune therapy in head and neck cancer: comparative mRNA expression analysis of RAGE and GAGE genes Identification of CDK4 sequences involved in cyclin D1 and p16 binding PRAME, a gene encoding an antigen recognized on a human melanoma by cytolytic T cells, is expressed in acute leukaemia cells A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis Pre-existing immunity to tyrosinase-related protein (TRP)-2, a new TRP-2 isoform, and the NY-ESO-1 melanoma antigen in a patient with a dramatic response to immunotherapy Cooperation of DLC1 and CDK6 affects breast cancer clinical outcome Genetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell number Biochemical identification of a mutated human melanoma antigen recognized by CD4(+) T cells.The immunodominant antigen of an ultraviolet-induced regressor tumor is generated by a somatic point mutation in the DEAD box helicase p68 Identification of cyclin B1 as a shared human epithelial tumor-associated antigen recognized by T cells.The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition.An essential role for Ink4 and Cip/Kip cell-cycle inhibitors in preventing replicative stress

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A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

http://www.wikidata.org/entity/Q28296086

description

1995 nî lūn-bûn

@nan

1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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1995年の論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年论文

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name

A p16INK4a-insensitive CDK4 mu ...... ymphocytes in a human melanoma

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A p16INK4a-insensitive CDK4 mu ...... ymphocytes in a human melanoma

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A p16INK4a-insensitive CDK4 mu ...... ymphocytes in a human melanoma

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type

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A p16INK4a-insensitive CDK4 mu ...... ymphocytes in a human melanoma

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A p16INK4a-insensitive CDK4 mu ...... ymphocytes in a human melanoma

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A p16INK4a-insensitive CDK4 mu ...... ymphocytes in a human melanoma

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A p16INK4a-insensitive CDK4 mu ...... ymphocytes in a human melanoma

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A p16INK4a-insensitive CDK4 mu ...... ymphocytes in a human melanoma

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A p16INK4a-insensitive CDK4 mu ...... ymphocytes in a human melanoma

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P2860

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

WAF1, a potential mediator of p53 tumor suppression

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

A cell cycle regulator potentially involved in genesis of many tumor types

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