The use of isotope effects to determine enzyme mechanisms
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Advances in kinetic isotope effect measurement techniques for enzyme mechanism studyChemistry and biochemistry of 13C hyperpolarized magnetic resonance using dynamic nuclear polarizationA Radical Transfer Pathway in Spore Photoproduct LyaseInsights into the Activity Change of Spore Photoproduct Lyase Induced by Mutations at a Peripheral Glycine ResidueEnzymatic transition states and dynamic motion in barrier crossing.Detailed Mechanistic Study of the Non-enzymatic Formation of the Discoipyrrole Family of Natural Products.Inaccuracies in selected ion monitoring determination of isotope ratios obviated by profile acquisition: nucleotide 18O/16O measurements.Nitrate reductase (15)N discrimination in Arabidopsis thaliana, Zea mays, Aspergillus niger, Pichea angusta, and Escherichia coli.Ab initio path-integral calculations of kinetic and equilibrium isotope effects on base-catalyzed RNA transphosphorylation models.Kinetic analysis of lauric acid hydroxylation by human cytochrome P450 4A11Intramolecular 13C pattern in hexoses from autotrophic and heterotrophic C3 plant tissues.The use of isotopes in the determination of absolute bioavailability of drugs in humans.Mechanistic studies of 1-aminocyclopropane-1-carboxylate deaminase: characterization of an unusual pyridoxal 5'-phosphate-dependent reaction.On the chemical mechanism of succinic semialdehyde dehydrogenase (GabD1) from Mycobacterium tuberculosisExperimental evidence for a hydride transfer mechanism in plant glycolate oxidase catalysisNonperfect synchronization of reaction center rehybridization in the transition state of the hydride transfer catalyzed by dihydrofolate reductase.Multidimensional tunneling, recrossing, and the transmission coefficient for enzymatic reactionsImpact of kinetic isotope effects in isotopic studies of metabolic systems.Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8.Transition-state variation in human, bovine, and Plasmodium falciparum adenosine deaminases.Measuring specificity in multi-substrate/product systems as a tool to investigate selectivity in vivo.Experimental and computational analysis of the transition state for ribonuclease A-catalyzed RNA 2'-O-transphosphorylation.Transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases.Experimental analyses of the chemical dynamics of ribozyme catalysisInfluence of mass transfer on stable isotope fractionation.Determination of relative rate constants for in vitro RNA processing reactions by internal competition.Integration of kinetic isotope effect analyses to elucidate ribonuclease mechanism.Deuterated detergents for structural and functional studies of membrane proteins: Properties, chemical synthesis and applications.Mechanistic Studies of an Amine Oxidase Derived from d-Amino Acid Oxidase.Inactivation of peptidylglycine α-hydroxylating monooxygenase by cinnamic acid analogs.Isotope effect analyses provide evidence for an altered transition state for RNA 2'-O-transphosphorylation catalyzed by Zn(2+).A complex of methylthioadenosine/S-adenosylhomocysteine nucleosidase, transition state analogue, and nucleophilic water identified by mass spectrometry.Determination of hepatitis delta virus ribozyme N(-1) nucleobase and functional group specificity using internal competition kineticsMechanistic studies of the flavoenzyme tryptophan 2-monooxygenase: deuterium and 15N kinetic isotope effects on alanine oxidation by an L-amino acid oxidase.Pyrophosphate interactions at the transition states of Plasmodium falciparum and human orotate phosphoribosyltransferasesOptimization of high-throughput sequencing kinetics for determining enzymatic rate constants of thousands of RNA substrates.Arsenate and phosphate as nucleophiles at the transition states of human purine nucleoside phosphorylaseSubstantial (13) C/(12) C and D/H fractionation during anaerobic oxidation of methane by marine consortia enriched in vitro.Transition-state analysis of S. pneumoniae 5'-methylthioadenosine nucleosidaseTransition-state analysis of Trypanosoma cruzi uridine phosphorylase-catalyzed arsenolysis of uridine.
P2860
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P2860
The use of isotope effects to determine enzyme mechanisms
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The use of isotope effects to determine enzyme mechanisms
@ast
The use of isotope effects to determine enzyme mechanisms
@en
The use of isotope effects to determine enzyme mechanisms
@nl
type
label
The use of isotope effects to determine enzyme mechanisms
@ast
The use of isotope effects to determine enzyme mechanisms
@en
The use of isotope effects to determine enzyme mechanisms
@nl
prefLabel
The use of isotope effects to determine enzyme mechanisms
@ast
The use of isotope effects to determine enzyme mechanisms
@en
The use of isotope effects to determine enzyme mechanisms
@nl
P1476
The use of isotope effects to determine enzyme mechanisms
@en
P2093
W W Cleland
P356
10.1016/J.ABB.2004.08.027
P407
P577
2005-01-01T00:00:00Z