Safety issues and prospects for future generations of PPAR modulators
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Polyacetylenes from Notopterygium incisum--new selective partial agonists of peroxisome proliferator-activated receptor-gammaMBX-102/JNJ39659100, a novel non-TZD selective partial PPAR-γ agonist lowers triglyceride independently of PPAR-α activationIdentification of isosilybin a from milk thistle seeds as an agonist of peroxisome proliferator-activated receptor gammaThe role of peroxisome proliferator-activated receptors in carcinogenesis and chemopreventionMinireview: the case for obesogensEndocrine disrupters as obesogensIs the risk of cardiovascular disease altered with anti-inflammatory therapies? Insights from rheumatoid arthritisUnlock the Thermogenic Potential of Adipose Tissue: Pharmacological Modulation and Implications for Treatment of Diabetes and ObesityModulating peroxisome proliferator-activated receptors for therapeutic benefit? Biology, clinical experience, and future prospectsPeroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications--a reviewCancer risk for patients using thiazolidinediones for type 2 diabetes: a meta-analysisPPAR-γ as a therapeutic target in cardiovascular disease: evidence and uncertaintyThe association between type 2 diabetes mellitus and women cancer: the epidemiological evidences and putative mechanismsDiabetes and cancer: a consensus report.Differential Role of Adipose Tissues in Obesity and Related Metabolic and Vascular ComplicationsPPARγ as a therapeutic target to rescue mitochondrial function in neurological diseaseEndocrine disrupting chemicals and the developmental programming of adipogenesis and obesityDesign novel dual agonists for treating type-2 diabetes by targeting peroxisome proliferator-activated receptors with core hopping approachCyanide-induced death of dopaminergic cells is mediated by uncoupling protein-2 up-regulation and reduced Bcl-2 expressionRosiglitazone for active ulcerative colitis: a randomized placebo-controlled trial.PPARγ agonists regulate the expression of stemness and differentiation genes in brain tumour stem cellsMBX-102/JNJ39659100, a novel peroxisome proliferator-activated receptor-ligand with weak transactivation activity retains antidiabetic properties in the absence of weight gain and edema.Artemisia scoparia enhances adipocyte development and endocrine function in vitro and enhances insulin action in vivoThe PPAR alpha agonist gemfibrozil is an ineffective treatment for spinal cord injured mice.Thiazolidinedione treatment and constitutive-PPARgamma activation induces ectopic adipogenesis and promotes age-related thymic involution.High-fat and obesogenic diets: current and future strategies to fight obesity and diabetes.Effects of thiazolidinediones on polycystic ovary syndrome: a meta-analysis of randomized placebo-controlled trials.New peroxisome proliferator-activated receptor agonists: potential treatments for atherogenic dyslipidemia and non-alcoholic fatty liver disease.Identification of novel multitargeted PPARα/γ/δ pan agonists by core hopping of rosiglitazoneDiscontinued in 2013: diabetic drugs.Cohort study of pioglitazone and cancer incidence in patients with diabetesDrugs and their molecular targets: an updated overview.Childhood obesity and environmental chemicals.The novel PPAR α/γ dual agonist MHY 966 modulates UVB-induced skin inflammation by inhibiting NF-κB activity.Efficacy and safety of lobeglitazone monotherapy in patients with type 2 diabetes mellitus over 24-weeks: a multicenter, randomized, double-blind, parallel-group, placebo controlled trial.Peroxisome proliferator-activated receptors and cancer: challenges and opportunitiesSuccessful drug development despite adverse preclinical findings part 2: examples.Peroxisome proliferator-activated receptors, metabolic syndrome and cardiovascular disease.Delivery of Polymeric Nanoparticles to Target Vascular Diseases.Polymer-based therapeutics: nanoassemblies and nanoparticles for management of atherosclerosis
P2860
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P2860
Safety issues and prospects for future generations of PPAR modulators
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Safety issues and prospects for future generations of PPAR modulators
@ast
Safety issues and prospects for future generations of PPAR modulators
@en
Safety issues and prospects for future generations of PPAR modulators
@nl
type
label
Safety issues and prospects for future generations of PPAR modulators
@ast
Safety issues and prospects for future generations of PPAR modulators
@en
Safety issues and prospects for future generations of PPAR modulators
@nl
prefLabel
Safety issues and prospects for future generations of PPAR modulators
@ast
Safety issues and prospects for future generations of PPAR modulators
@en
Safety issues and prospects for future generations of PPAR modulators
@nl
P2093
P3181
P1476
Safety issues and prospects for future generations of PPAR modulators
@en
P2093
Anne Rubenstrunk
Dean W Hum
P304
P3181
P356
10.1016/J.BBALIP.2007.02.003
P407
P577
2007-08-01T00:00:00Z