The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis
about
Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2Molecular cloning of human homolog of yeast GAA1 which is required for attachment of glycosylphosphatidylinositols to proteinsHuman and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutantsPIG-B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchorPIG-A and PIG-H, which participate in glycosylphosphatidylinositol anchor biosynthesis, form a protein complex in the endoplasmic reticulumCarboxyl-terminal targeting and novel post-translational processing of JAW1, a lymphoid protein of the endoplasmic reticulumThe first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1.PIG-M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER.Stimulation of glycogen synthesis by insulin in human erythroleukemia cells requires the synthesis of glycosyl-phosphatidylinositolParoxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A geneParoxysmal nocturnal hemoglobinuria from bench to bedsideThe affected gene underlying the class K glycosylphosphatidylinositol (GPI) surface protein defect codes for the GPI transamidaseHow I treat paroxysmal nocturnal hemoglobinuriaMutation analysis of the PIG-A gene in Korean patients with paroxysmal nocturnal haemoglobinuriaRecent advances in the pathogenesis and treatment of paroxysmal nocturnal hemoglobinuriaSugar activation and glycosylation in PlasmodiumMembrane attack by complement: the assembly and biology of terminal complement complexesBiosynthesis and deficiencies of glycosylphosphatidylinositolGpi1, a Saccharomyces cerevisiae protein that participates in the first step in glycosylphosphatidylinositol anchor synthesis.Gpi19, the Saccharomyces cerevisiae homologue of mammalian PIG-P, is a subunit of the initial enzyme for glycosylphosphatidylinositol anchor biosynthesis.Ynl038wp (Gpi15p) is the Saccharomyces cerevisiae homologue of human Pig-Hp and participates in the first step in glycosylphosphatidylinositol assembly.GUP1 of Saccharomyces cerevisiae encodes an O-acyltransferase involved in remodeling of the GPI anchor.Photoaffinity labelling with P3-(4-azidoanilido)uridine 5'-triphosphate identifies gpi3p as the UDP-GlcNAc-binding subunit of the enzyme that catalyses formation of GlcNAc-phosphatidylinositol, the first glycolipid intermediate in glycosylphosphatidySaccharomyces cerevisiae GPI10, the functional homologue of human PIG-B, is required for glycosylphosphatidylinositol-anchor synthesisDeletion of GPI7, a yeast gene required for addition of a side chain to the glycosylphosphatidylinositol (GPI) core structure, affects GPI protein transport, remodeling, and cell wall integrity.Genes for glycosylphosphatidylinositol toxin biosynthesis in Plasmodium falciparum.Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insightsPIG-A mutations in paroxysmal nocturnal hemoglobinuria and in normal hematopoiesisPurification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei.Expression cloning of PIG-L, a candidate N-acetylglucosaminyl-phosphatidylinositol deacetylaseGPI1 stabilizes an enzyme essential in the first step of glycosylphosphatidylinositol biosynthesisThe rate of spontaneous mutations in human myeloid cellsUnique motifs identify PIG-A proteins from glycosyltransferases of the GT4 familyA case of paroxysmal nocturnal hemoglobinuria presenting with intra-abdominal bleeding due to splenic rupture, developing renal infarct.Selective splenic artery embolization for the treatment of thrombocytopenia and hypersplenism in paroxysmal nocturnal hemoglobinuria.Cerebral Stroke in a Teenage Girl with Paroxysmal Nocturnal Hemoglobinuria.A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC modelClonal evolution of aplastic anaemia to myelodysplasia/acute myeloid leukaemia and paroxysmal nocturnal haemoglobinuria.Biosynthesis of glycosylphosphatidylinositols in mammals and unicellular microbes.PathLocdb: a comprehensive database for the subcellular localization of metabolic pathways and its application to multiple localization analysis.
P2860
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P2860
The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis
description
1993 nî lūn-bûn
@nan
1993 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis
@ast
The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis
@en
The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis
@nl
type
label
The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis
@ast
The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis
@en
The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis
@nl
prefLabel
The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis
@ast
The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis
@en
The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis
@nl
P2093
P356
P1433
P1476
The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis
@en
P2093
M Takahashi
T Kinoshita
P304
P356
10.1126/SCIENCE.7680492
P407
P577
1993-02-26T00:00:00Z