Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal
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Identification of a family of sorting nexin molecules and characterization of their association with receptorsHuman phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activityA natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxisRole for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damageIdentification and characterization of SNX15, a novel sorting nexin involved in protein traffickingIdentification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activationThe SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytesDisruption of platelet-derived growth factor-dependent phosphatidylinositol 3-kinase and phospholipase Cγ 1 activity abolishes vascular smooth muscle cell proliferation and migration and attenuates neointima formation in vivoIdentification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transductionAcetylcholine muscarinic m1 receptor regulation of cyclic AMP synthesis controls growth factor stimulation of Raf activityT-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motifThe 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase SypTwo signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptorConstruction of an SH2 domain-binding site with mixed specificityPDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AAPhospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for SykA human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting systemProtein tyrosine phosphatase 1B interacts with and is tyrosine phosphorylated by the epidermal growth factor receptorInteraction of the Flt-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in bindingCTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cellsCloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmanninThe extended protein kinase C superfamilyMultiple forms of p55PIK, a regulatory subunit of phosphoinositide 3-kinase, are generated by alternative initiation of translationConvergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway.Vav family proteins couple to diverse cell surface receptorsRequirement of phospholipase C gamma, the tyrosine phosphatase Syp and the adaptor proteins Shc and Nck for PDGF-induced DNA synthesis: evidence for the existence of Ras-dependent and Ras-independent pathwaysGenomic structure and cloned cDNAs predict that four variants in the kinase domain of serine/threonine kinase receptors arise by alternative splicing and poly(A) additionProtein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to RasIdentification of c-erbB-3 binding sites for phosphatidylinositol 3'-kinase and SHC using an EGF receptor/c-erbB-3 chimeraTyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activationGenetic analysis of a phosphatidylinositol 3-kinase SH2 domain reveals determinants of specificityMutagenic analysis of the roles of SH2 and SH3 domains in regulation of the Abl tyrosine kinaseCloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1Lambda-interacting protein, a novel protein that specifically interacts with the zinc finger domain of the atypical protein kinase C isotype lambda/iota and stimulates its kinase activity in vitro and in vivoThe structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinaseConstitutive phosphorylation of eps8 in tumor cell lines: relevance to malignant transformationIntegrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinaseThe Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and diseaseStimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells
P2860
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P2860
Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal
description
1993 nî lūn-bûn
@nan
1993 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Phospholipase C-gamma 1 and ph ...... GF receptor's mitogenic signal
@ast
Phospholipase C-gamma 1 and ph ...... GF receptor's mitogenic signal
@en
Phospholipase C-gamma 1 and ph ...... GF receptor's mitogenic signal
@nl
type
label
Phospholipase C-gamma 1 and ph ...... GF receptor's mitogenic signal
@ast
Phospholipase C-gamma 1 and ph ...... GF receptor's mitogenic signal
@en
Phospholipase C-gamma 1 and ph ...... GF receptor's mitogenic signal
@nl
prefLabel
Phospholipase C-gamma 1 and ph ...... GF receptor's mitogenic signal
@ast
Phospholipase C-gamma 1 and ph ...... GF receptor's mitogenic signal
@en
Phospholipase C-gamma 1 and ph ...... GF receptor's mitogenic signal
@nl
P1433
P1476
Phospholipase C-gamma 1 and ph ...... GF receptor's mitogenic signal
@en
P2093
A Kazlauskas
P304
P356
10.1016/0092-8674(93)90232-F
P407
P577
1993-04-01T00:00:00Z