Creating designed zinc-finger nucleases with minimal cytotoxicity
about
Origins of Programmable Nucleases for Genome EngineeringCurrent translational and clinical practices in hematopoietic cell and gene therapyOligo/polynucleotide-based gene modification: strategies and therapeutic potentialThe I-TevI nuclease and linker domains contribute to the specificity of monomeric TALENsHybrid lentivirus-phiC31-int-NLS vector allows site-specific recombination in murine and human cells but induces DNA damage.Design of a colicin E7 based chimeric zinc-finger nucleaseSelection-independent generation of gene knockout mouse embryonic stem cells using zinc-finger nucleases.Gene therapy using stem cellsVersatile and efficient genome editing in human cells by combining zinc-finger nucleases with adeno-associated viral vectors.Generation and genetic engineering of human induced pluripotent stem cells using designed zinc finger nucleases.Emerging therapies for mitochondrial disorders.Comparing zinc finger nucleases and transcription activator-like effector nucleases for gene targeting in Drosophila.Zinc Finger Nucleases: Tailor-made for Gene TherapyGeneration of novel nucleases with extended specificity by rational and combinatorial strategies.Cell Biology Symposium: Zinc finger nucleases to create custom-designed modifications in the swine (Sus scrofa) genome.Zinc finger nucleases: looking toward translation.Restriction endonucleases: natural and directed evolution.Prospect of induced pluripotent stem cell genetic repair to cure genetic diseases.Genome modifications in plant cells by custom-made restriction enzymes.Targeted gene therapies: tools, applications, optimizationMolecular farming of human cytokines and blood products from plants: challenges in biosynthesis and detection of plant-produced recombinant proteins.Nuclease-mediated genome editing: At the front-line of functional genomics technology.Programmable Site-Specific Nucleases for Targeted Genome Engineering in Higher Eukaryotes.TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models.Enhanced gene disruption by programmable nucleases delivered by a minicircle vector.Male-sterile maize plants produced by targeted mutagenesis of the cytochrome P450-like gene (MS26) using a re-designed I-CreI homing endonuclease.Obligate ligation-gated recombination (ObLiGaRe): custom-designed nuclease-mediated targeted integration through nonhomologous end joining.Site- and strand-specific nicking of DNA by fusion proteins derived from MutH and I-SceI or TALE repeatsCCR5 Gene Editing of Resting CD4(+) T Cells by Transient ZFN Expression From HIV Envelope Pseudotyped Nonintegrating Lentivirus Confers HIV-1 Resistance in Humanized MiceTargeted Myostatin Gene Editing in Multiple Mammalian Species Directed by a Single Pair of TALE Nucleases.A novel zinc-finger nuclease platform with a sequence-specific cleavage module.Using CRISPR/Cas in three dimensions: towards synthetic plant genomes, transcriptomes and epigenomes.Chemical Approach to Biological Safety: Molecular-Level Control of an Integrated Zinc Finger Nuclease.
P2860
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P2860
Creating designed zinc-finger nucleases with minimal cytotoxicity
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Creating designed zinc-finger nucleases with minimal cytotoxicity
@ast
Creating designed zinc-finger nucleases with minimal cytotoxicity
@en
Creating designed zinc-finger nucleases with minimal cytotoxicity
@nl
type
label
Creating designed zinc-finger nucleases with minimal cytotoxicity
@ast
Creating designed zinc-finger nucleases with minimal cytotoxicity
@en
Creating designed zinc-finger nucleases with minimal cytotoxicity
@nl
prefLabel
Creating designed zinc-finger nucleases with minimal cytotoxicity
@ast
Creating designed zinc-finger nucleases with minimal cytotoxicity
@en
Creating designed zinc-finger nucleases with minimal cytotoxicity
@nl
P2093
P2860
P3181
P1476
Creating designed zinc-finger nucleases with minimal cytotoxicity
@en
P2093
Karthikeyan Kandavelou
Raja Rajenderan
Sivaprakash Ramalingam
Srinivasan Chandrasegaran
P2860
P304
P3181
P356
10.1016/J.JMB.2010.10.043
P407
P577
2011-01-21T00:00:00Z