Molecular cloning of a novel trypsin-like serine protease (neurosin) preferentially expressed in brain
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Localization of a new prostate-specific antigen-related serine protease gene, KLK4, is evidence for an expanded human kallikrein gene family cluster on chromosome 19q13.3-13.4Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4The spectrum of human kallikrein 6 (zyme/protease M/neurosin) expression in human tissues as assessed by immunohistochemistryThe structure of human prokallikrein 6 reveals a novel activation mechanism for the kallikrein familyHigher expression of human kallikrein 10 in breast cancer tissue predicts tamoxifen resistanceKallikreins are associated with secondary progressive multiple sclerosis and promote neurodegenerationImmunofluorometric quantitation and histochemical localisation of kallikrein 6 protein in ovarian cancer tissue: a new independent unfavourable prognostic biomarkerCrystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous systemCrystal structure of neuropsin, a hippocampal protease involved in kindling epileptogenesisThe new kallikrein-like gene, KLK-L2. Molecular characterization, mapping, tissue expression, and hormonal regulationAlternative splicing isoforms of hippostasin (PRSS20/KLK11) in prostate cancer cell linesDecreased cerebrospinal fluid levels of neurosin (KLK6), an aging-related protease, as a possible new risk factor for Alzheimer's diseaseMultiple promoters regulate tissue-specific alternative splicing of the human kallikrein gene, KLK11/hippostasinCloning and characterization of mouse klk27, a novel tissue kallikrein expressed in testicular Leydig cells and exhibiting chymotrypsin-like specificityThe axonally secreted serine proteinase inhibitor, neuroserpin, inhibits plasminogen activators and plasmin but not thrombin.Characterization of a recombinant soluble form of human placental leucine aminopeptidase/oxytocinase expressed in Chinese hamster ovary cells.Molecular and biochemical characterization of a serine proteinase predominantly expressed in the medulla oblongata and cerebellar white matter of mouse brain.Serine proteases in rodent hippocampus.In silico analysis of the human kallikrein gene 6.Substrate specificity of human kallikreins 1 and 6 determined by phage display.A novel form of human neuropsin, a brain-related serine protease, is generated by alternative splicing and is expressed preferentially in human adult brain.Enhanced hippocampal long-term potentiation and learning by increased neuronal expression of tissue-type plasminogen activator in transgenic mice.Cloning and characterization of the cDNA and gene for human epitheliasin.A novel serine protease highly expressed in the pancreas is expressed in various kinds of cancer cells.Low CSF levels of both α-synuclein and the α-synuclein cleaving enzyme neurosin in patients with synucleinopathyAccumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1.Human tissue kallikreins and testicular cancer.Expression of trypsin by epithelial cells of various tissues, leukocytes, and neurons in human and mouseThe tissue kallikrein family of serine proteases: functional roles in human disease and potential as clinical biomarkers.Lentivirus mediated delivery of neurosin promotes clearance of wild-type α-synuclein and reduces the pathology in an α-synuclein model of LBD.Correlation of hK6 expression with tumor recurrence and prognosis in advanced gastric cancerKLK6 and KLK13 predict tumor recurrence in epithelial ovarian carcinoma.Identification of human tissue kallikrein 6 as a potential marker of laryngeal cancer based on the relevant secretory/releasing protein database.Endothelin-converting enzymes degrade α-synuclein and are reduced in dementia with Lewy bodies.Kallikrein-related peptidase 6 (KLK6)gene expression in intracranial tumors.Upregulation and secretion of kallikrein-related peptidase 6 (KLK6) in gastric cancer.Up-regulation and clinical significance of serine protease kallikrein 6 in colon cancer.Virtual Screening and X-ray Crystallography for Human Kallikrein 6 Inhibitors with an Amidinothiophene P1 Group.cAMP-dependent regulation of spinesin/TMPRSS5 gene expression in astrocytes.Agonists of proteinase-activated receptor 2 induce TNF-alpha secretion from astrocytoma cells.
P2860
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P2860
Molecular cloning of a novel trypsin-like serine protease (neurosin) preferentially expressed in brain
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Molecular cloning of a novel t ...... ferentially expressed in brain
@ast
Molecular cloning of a novel t ...... ferentially expressed in brain
@en
Molecular cloning of a novel t ...... ferentially expressed in brain
@nl
type
label
Molecular cloning of a novel t ...... ferentially expressed in brain
@ast
Molecular cloning of a novel t ...... ferentially expressed in brain
@en
Molecular cloning of a novel t ...... ferentially expressed in brain
@nl
prefLabel
Molecular cloning of a novel t ...... ferentially expressed in brain
@ast
Molecular cloning of a novel t ...... ferentially expressed in brain
@en
Molecular cloning of a novel t ...... ferentially expressed in brain
@nl
P2093
P1476
Molecular cloning of a novel t ...... ferentially expressed in brain
@en
P2093
H Nakazato
K Yamashiro
M Tsujimoto
N Tsuruoka
N Yamaguchi
Y Yamamura
P356
10.1016/S0167-4781(96)00187-X
P407
P577
1997-01-03T00:00:00Z