Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia - Wikidata - awgldk - TriplyDB

Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia

Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia

http://www.wikidata.org/entity/Q28302174

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CCN3 impairs osteoblast and stimulates osteoclast differentiation to favor breast cancer metastasis to bone WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity Functions and mechanisms of action of CCN matricellular proteins Nephroblastoma overexpressed (Nov) inactivation sensitizes osteoblasts to bone morphogenetic protein-2, but nov is dispensable for skeletal homeostasis Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets Long-Lasting WNT-TCF Response Blocking and Epigenetic Modifying Activities of Withanolide F in Human Cancer Cells CCN3 protein participates in bone regeneration as an inhibitory factor Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene Notch and the skeleton.Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells Connective tissue growth factor is a target of notch signaling in cells of the osteoblastic lineage.The CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis.Connective tissue growth factor is required for skeletal development and postnatal skeletal homeostasis in male mice.Nephroblastoma overexpressed (Nov) induces gremlin in ST-2 stromal cell lines by post-transcriptional mechanisms Plasma NOV/CCN3 levels are closely associated with obesity in patients with metabolic disorders.Temporal and spatial expression of CCN genes in zebrafish.Targeted mutation of NOV/CCN3 in mice disrupts joint homeostasis and causes osteoarthritis-like disease.Fibulin-1 is required for bone formation and Bmp-2-mediated induction of Osterix.WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling.CONNEXIN 43 AND BONE: NOT JUST A GAP JUNCTION PROTEIN.CCN3 modulates bone turnover and is a novel regulator of skeletal metastasis An essential role for the association of CD47 to SHPS-1 in skeletal remodeling.Gender-specific changes in bone turnover and skeletal architecture in igfbp-2-null mice.TSG-6 regulates bone remodeling through inhibition of osteoblastogenesis and osteoclast activation Notch Signaling and the Skeleton.Osteogenic differentiation of mesenchymal stem cells promoted by overexpression of connective tissue growth factor.CCN3 and bone marrow cells.TGF-beta1 and WISP-1/CCN-4 can regulate each other's activity to cooperatively control osteoblast function The CCN family proteins: modulators of bone development and novel targets in bone-associated tumors Emerging role of CCN family proteins in tumorigenesis and cancer metastasis (Review).Agonists and Antagonists of TGF-β Family Ligands.CCN3/NOV small interfering RNA enhances fibrogenic gene expression in primary hepatic stellate cells and cirrhotic fat storing cell line CFSC.The gene expression profile induced by Wnt 3a in NIH 3T3 fibroblasts.Connective tissue growth factor enhances osteoblastogenesis in vitro.Characterization bone morphology in CCN5/WISP5 knockout mice.Structural analyses of von Willebrand factor C domains of collagen 2A and CCN3 reveal an alternative mode of binding to bone morphogenetic protein-2.CYR61/CCN1 Regulates Sclerostin Levels and Bone Maintenance.

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Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia

http://www.wikidata.org/entity/Q28302174

description

2007 nî lūn-bûn

@nan

2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հուլիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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name

Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia

@ast

Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia

@en

Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia

@nl

type

label

Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia

@ast

Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia

@en

Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia

@nl

prefLabel

Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia

@ast

Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia

@en

Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia

@nl

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P1433

Journal of Biological Chemistry

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Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia

@en

P2093

Anna Smerdel-Ramoya

http://www.w3.org/2001/XMLSchema#string

Deena Durant

http://www.w3.org/2001/XMLSchema#string

Ernesto Canalis

http://www.w3.org/2001/XMLSchema#string

Lisa Stadmeyer

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Sheila Rydziel

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Stefano Zanotti

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P2860

Connexin43 interacts with NOV: a possible mechanism for negative regulation of cell growth in choriocarcinoma cells

The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway

Signal transduction of bone morphogenetic protein receptors

Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes

Skeletal overexpression of gremlin impairs bone formation and causes osteopenia

Integrin-dependent functions of the angiogenic inducer NOV (CCN3): implication in wound healing

Proposal for a unified CCN nomenclature.

CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

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19762-72

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scholarly article

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10.1074/JBC.M700212200

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27

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P478

282

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Ernesto Canalis

Stefano Zanotti

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2007-07-06T00:00:00Z

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P698

17500060

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