The transcription factor, Nm23H2, binds to and activates the translocated c-myc allele in Burkitt's lymphoma
about
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcriptionMetastases suppressor NM23-H2 interaction with G-quadruplex DNA within c-MYC promoter nuclease hypersensitive element induces c-MYC expressionEpstein-Barr virus and Burkitt lymphomaNM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III13'-Phosphorylated nucleotides are tight binding inhibitors of nucleoside diphosphate kinase activityCooperative E-box regulation of human GLI1 by TWIST and USFHeat stress response in pea involves interaction of mitochondrial nucleoside diphosphate kinase with a novel 86-kilodalton proteinMultiple functions of Nm23-H1 are regulated by oxido-reduction systemPuF, an antimetastatic and developmental signaling protein, interacts with the Alzheimer's amyloid-β precursor protein via a tissue-specific proximal regulatory element (PRE)NM23-H1 and NM23-H2 repress transcriptional activities of nuclease-hypersensitive elements in the platelet-derived growth factor-A promoter.Protein complexes associated with the Kaposi's sarcoma-associated herpesvirus-encoded LANA.Differentiation inhibitory factor Nm23 as a prognostic factor for acute myeloid leukemia.Structure of the biologically relevant G-quadruplex in the c-MYC promoter.Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?The guanine-quadruplex structure in the human c-myc gene's promoter is converted into B-DNA form by the human poly(ADP-ribose)polymerase-1.Diva/BclB regulates differentiation by inhibiting NDPKB/Nm23H2-mediated neuronal differentiation in PC-12 cells.Decrease in nucleoside diphosphate kinase (NDPK/nm23) expression during hematopoietic maturation.Relationship of nm23 to proteolytic factors, proliferation and motility in breast cancer tissues and cell lines.Escherichia coli nucleoside diphosphate kinase is a uracil-processing DNA repair nucleaseMutational analysis of NM23-H2/NDP kinase identifies the structural domains critical to recognition of a c-myc regulatory element.Mutations in the G-quadruplex silencer element and their relationship to c-MYC overexpression, NM23 repression, and therapeutic rescueSingle strand DNA specificity analysis of human nucleoside diphosphate kinase B.The in vitro DNA binding properties of NDP kinase are related to its oligomeric state.Extracellular NM23 Protein as a Therapeutic Target for Hematologic Malignancies.Secreted variant of nucleoside diphosphate kinase from the intracellular parasitic nematode Trichinella spiralis.Mechanisms of non-metastatic 2 (NME2)-mediated control of metastasis across tumor types.Phosphoglycerate mutase-derived polypeptide inhibits glycolytic flux and induces cell growth arrest in tumor cell lines.A Myc-associated zinc finger protein-related factor binding site is required for the deregulation of c-myc expression by the immunoglobulin heavy chain gene enhancers in Burkitt's lymphoma.NF-kappa B activity is required for the deregulation of c-myc expression by the immunoglobulin heavy chain enhancer.Extensive association analysis between the CETP gene and coronary heart disease phenotypes reveals several putative functional polymorphisms and gene-environment interaction.Structure and mutational analysis of a plant mitochondrial nucleoside diphosphate kinase. Identification of residues involved in serine phosphorylation and oligomerization.NM23/NDPK proteins in transcription regulatory functions and chromatin modulation: emerging trends.Nuclear functions of NME proteins.Characterization and cloning of a nucleoside-diphosphate kinase targeted to matrix of mitochondria in pigeon.A point mutation of human nucleoside diphosphate kinase A found in aggressive neuroblastoma affects protein folding.Investigation of mRNA quadruplex formation in Escherichia coli.Proteomic profiling of skeletal and cardiac muscle in cancer cachexia: alterations in sarcomeric and mitochondrial protein expression.Nucleoside diphosphate kinase III is localized to the inter-membrane space in plant mitochondria
P2860
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P2860
The transcription factor, Nm23H2, binds to and activates the translocated c-myc allele in Burkitt's lymphoma
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The transcription factor, Nm23 ...... c allele in Burkitt's lymphoma
@ast
The transcription factor, Nm23 ...... c allele in Burkitt's lymphoma
@en
The transcription factor, Nm23 ...... c allele in Burkitt's lymphoma
@nl
type
label
The transcription factor, Nm23 ...... c allele in Burkitt's lymphoma
@ast
The transcription factor, Nm23 ...... c allele in Burkitt's lymphoma
@en
The transcription factor, Nm23 ...... c allele in Burkitt's lymphoma
@nl
prefLabel
The transcription factor, Nm23 ...... c allele in Burkitt's lymphoma
@ast
The transcription factor, Nm23 ...... c allele in Burkitt's lymphoma
@en
The transcription factor, Nm23 ...... c allele in Burkitt's lymphoma
@nl
P2093
P2860
P356
P1476
The transcription factor, Nm23 ...... c allele in Burkitt's lymphoma
@en
P2093
P2860
P304
P356
10.1074/JBC.270.22.13392
P407
P577
1995-06-02T00:00:00Z