Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase - Wikidata - awgldk - TriplyDB

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

http://www.wikidata.org/entity/Q28302589

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Hypoxia-inducible C-to-U coding RNA editing downregulates SDHB in monocytes Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells Pheochromocytomas and secreting paragangliomas Sequence variation in human succinate dehydrogenase genes: evidence for long-term balancing selection on SDHA The FH mutation database: an online database of fumarate hydratase mutations involved in the MCUL (HLRCC) tumor syndrome and congenital fumarase deficiency The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates Single-gene disorders: what role could moonlighting enzymes play?miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity Applications of metabolomics in cancer research Understanding the Warburg effect: the metabolic requirements of cell proliferation State of the science: an update on renal cell carcinoma Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases HIF-1: upstream and downstream of cancer metabolism Germline mutations and variants in the succinate dehydrogenase genes in Cowden and Cowden-like syndromes Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas Mitochondrial DNA mutations in cancer.Targeting Cancer Metabolism - Revisiting the Warburg Effects Metabolic, autophagic, and mitophagic activities in cancer initiation and progression Mitochondrial metabolic remodeling in response to genetic and environmental perturbations Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases Hypoxia and Hypoxia-Inducible Factors in Leukemias Energy metabolism in neuroblastoma and Wilms tumor Cancer Metabolism: A Modeling Perspective Hypoxia-inducible factor 1-mediated characteristic features of cancer cells for tumor radioresistance Mitochondria-controlled signaling mechanisms of brain protection in hypoxia Decoding Warburg's hypothesis: tumor-related mutations in the mitochondrial respiratory chain Dysregulated metabolism contributes to oncogenesis Succinate Dehydrogenase Loss in Familial Paraganglioma: Biochemistry, Genetics, and Epigenetics 15 YEARS OF PARAGANGLIOMA: Clinical manifestations of paraganglioma syndromes types 1-5 Lung cell hypoxia: role of mitochondrial reactive oxygen species signaling in triggering responses Autophagy paradox and ceramide Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel?Tumors of the neural crest: Common themes in development and cancer Mitochondria in the regulation of innate and adaptive immunity Autophagy and disease: always two sides to a problem

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P2860

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

http://www.wikidata.org/entity/Q28302589

description

2005 nî lūn-bûn

@nan

2005 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2005 թվականի հունվարին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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name

Succinate links TCA cycle dysf ...... g HIF-alpha prolyl hydroxylase

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Succinate links TCA cycle dysf ...... g HIF-alpha prolyl hydroxylase

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Succinate links TCA cycle dysf ...... g HIF-alpha prolyl hydroxylase

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Succinate links TCA cycle dysf ...... g HIF-alpha prolyl hydroxylase

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Succinate links TCA cycle dysf ...... g HIF-alpha prolyl hydroxylase

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Succinate links TCA cycle dysf ...... g HIF-alpha prolyl hydroxylase

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Succinate links TCA cycle dysf ...... g HIF-alpha prolyl hydroxylase

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Succinate links TCA cycle dysf ...... g HIF-alpha prolyl hydroxylase

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J.CCR.2004.11.022

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Succinate links TCA cycle dysf ...... g HIF-alpha prolyl hydroxylase

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Craig B Thompson

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David G Watson

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Elaine D MacKenzie

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Eyal Gottlieb

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Houda Boulahbel

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Kyle D Mansfield

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M Celeste Simon

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Mary A Selak

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Sean M Armour

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Yi Pan

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scholarly article

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