Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition - Wikidata - awgldk - TriplyDB

Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition

Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition

http://www.wikidata.org/entity/Q28302883

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Potentiation of Gamma Aminobutyric Acid Receptors (GABAAR) by Ethanol: How Are Inhibitory Receptors Affected?Epileptic encephalopathy de novo GABRB mutations impair GABAA receptor function Molecular tools for GABAA receptors: High affinity ligands for β1-containing subtypes.Alcohol use disorders and current pharmacological therapies: the role of GABA(A) receptors.Novel QTL at chromosome 6p22 for alcohol consumption: Implications for the genetic liability of alcohol use disorders.GABAA receptor subtype involvement in addictive behaviour.Intermittent high-dose ethanol exposure increases ethanol preference in rats.Pharmacological characterisation of murine α4β1δ GABAA receptors expressed in Xenopus oocytes.Ionotropic GABA and Glutamate Receptor Mutations and Human Neurologic Diseases.Mechanisms of Neuroplasticity and Ethanol's Effects on Plasticity in the Striatum and Bed Nucleus of the Stria Terminalis.Histamine 1 receptor-Gβγ-cAMP/PKA-CFTR pathway mediates the histamine-induced resetting of the suprachiasmatic circadian clock.GABRB1 Single Nucleotide Polymorphism Associated with Altered Brain Responses (but not Performance) during Measures of Impulsivity and Reward Sensitivity in Human Adolescents.GABAA receptors and plasticity of inhibitory neurotransmission in the central nervous system.Genetics in PBC: what do the "risk genes" teach us?Alcohol dependence: molecular and behavioral evidence.Alcohol use disorder and GABAB receptor gene polymorphisms in an Italian sample: haplotype frequencies, linkage disequilibrium and association studies.GABAA Receptor Subtype Mechanisms and the Abuse-Related Effects of Ethanol: Genetic and Pharmacological Evidence.Loop G in the GABAA receptor α1 subunit influences gating efficacy.A tonic for anxiety.Nuclear Respiratory Factor 1 (NRF-1) Controls the Activity Dependent Transcription of the GABA-A Receptor Beta 1 Subunit Gene in Neurons

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Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition

http://www.wikidata.org/entity/Q28302883

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Mutations in the Gabrb1 gene p ...... ugh increased tonic inhibition

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Mutations in the Gabrb1 gene p ...... ugh increased tonic inhibition

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Mutations in the Gabrb1 gene p ...... ugh increased tonic inhibition

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type

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Mutations in the Gabrb1 gene p ...... ugh increased tonic inhibition

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Mutations in the Gabrb1 gene p ...... ugh increased tonic inhibition

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Mutations in the Gabrb1 gene p ...... ugh increased tonic inhibition

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Mutations in the Gabrb1 gene p ...... ugh increased tonic inhibition

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Mutations in the Gabrb1 gene p ...... ugh increased tonic inhibition

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Mutations in the Gabrb1 gene p ...... ugh increased tonic inhibition

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Nature Communications

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Mutations in the Gabrb1 gene p ...... ugh increased tonic inhibition

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Alastair M Hosie

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Alonso Martinez

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Amy Herlihy

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Claire I Dixon

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David N Stephens

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Edward P Maguire

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Howard C Thomas

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Hugh M D Gurling

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Iain Robinson

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Irene Guerrini

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P2860

Ethanol acts directly on extrasynaptic subtypes of GABAA receptors to increase tonic inhibition

Insertion of Inhbb into the Inhba locus rescues the Inhba-null phenotype and reveals new activin functions

Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus

Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations.

International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update

Activation of single heteromeric GABA(A) receptor ion channels by full and partial agonists

Bicuculline and gabazine are allosteric inhibitors of channel opening of the GABAA receptor

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse

Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14

Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcohol.

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scholarly article

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1800250

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10.1038/NCOMMS3816

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4

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Elizabeth M. C. Fisher

Andrew McQuillin

Quentin M Anstee

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2013-01-01T00:00:00Z

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258888862

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1041537000

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24281383

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alcohol consumption

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3843143

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