R (-)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine
about
Ketamine enantiomers in the rapid and sustained antidepressant effectsControversies of the Effect of Ketamine on CognitionTreatment-Resistant Major Depression: Rationale for NMDA Receptors as Targets and Nitrous Oxide as TherapyPotential of Glutamate-Based Drug Discovery for Next Generation AntidepressantsKetamine: 50 Years of Modulating the MindR-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effectsComparison of R-ketamine and rapastinel antidepressant effects in the social defeat stress model of depressionKetamine's antidepressant action: beyond NMDA receptor inhibitionS-Ketamine Rapidly Reverses Synaptic and Vascular Deficits of Hippocampus in Genetic Animal Model of Depression.Comparison of ketamine, 7,8-dihydroxyflavone, and ANA-12 antidepressant effects in the social defeat stress model of depression.Investigational drugs for treating major depressive disorder.Investigational drugs in recent clinical trials for treatment-resistant depression.Enantioselective inhibition of d-serine transport by (S)-ketamineThe distribution and clearance of (2S,6S)-hydroxynorketamine, an active ketamine metabolite, in Wistar ratsInvolvement of normalized NMDA receptor and mTOR-related signaling in rapid antidepressant effects of Yueju and ketamine on chronically stressed mice.The effect of imipramine, ketamine, and zinc in the mouse model of depressionKetamine: NMDA Receptors and Beyond.Antidepressant Effects of (+)-MK-801 and (-)-MK-801 in the Social Defeat Stress Model.Reduction of dopamine D2/3 receptor binding in the striatum after a single administration of esketamine, but not R-ketamine: a PET study in conscious monkeys.NMDA antagonists under investigation for the treatment of major depressive disorder.New Treatment Strategies of Depression: Based on Mechanisms Related to Neuroplasticity.Strategies to mitigate dissociative and psychotomimetic effects of ketamine in the treatment of major depressive episodes: a narrative review.Targeting glutamate signalling in depression: progress and prospects.Risks Associated with Misuse of Ketamine as a Rapid-Acting Antidepressant.Ketamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy.On the Eve of Upgrading Antidepressants: (R)-Ketamine and Its Metabolites.Rapid-onset antidepressant action of ketamine: potential revolution in understanding and future pharmacologic treatment of depression.The R-Stereoisomer of Ketamine as an Alternative for Ketamine for Treatment-resistant Major Depression.Reply to: Antidepressant Actions of Ketamine Versus Hydroxynorketamine.Reply to: Rapid antidepressant effects and abuse liability of ketaminePossible role of the gut microbiota-brain axis in the antidepressant effects of (R)-ketamine in a social defeat stress model.Comparison of (R)-ketamine and lanicemine on depression-like phenotype and abnormal composition of gut microbiota in a social defeat stress model.Intracellular Signaling Pathways Involved in (S)- and (R)-Ketamine Antidepressant Actions.Subanesthetic ketamine decreases the incentive-motivational value of reward-related cues.Ketamine and its metabolite (2R,6R)-hydroxynorketamine induce lasting alterations in glutamatergic synaptic plasticity in the mesolimbic circuit.Effects of a single bilateral infusion of R-ketamine in the rat brain regions of a learned helplessness model of depression.Letter to the Editor: R-ketamine: a rapid-onset and sustained antidepressant without risk of brain toxicity.Differential interaction with the serotonin system by S-ketamine, vortioxetine, and fluoxetine in a genetic rat model of depression.Lack of Antidepressant Effects of (2R,6R)-Hydroxynorketamine in a Rat Learned Helplessness Model: Comparison with (R)-Ketamine.5-Hydroxytryptamine-independent antidepressant actions of (R)-ketamine in a chronic social defeat stress model.
P2860
Q26746141-6E2E5872-69B9-4C00-BF03-06831658EB5EQ26749661-51BC60C1-94D3-48CD-B266-A6BEB0078B95Q26773084-9B4849B3-75DB-4E44-9BC5-AEED9268E2F9Q26782274-78F7F80C-23B6-4FD9-B971-F8F745342211Q28077524-6F735C8E-8E52-4BA2-9973-31F5857C773CQ28266846-252C2867-CA70-47BB-9DB0-396844184243Q28277636-F93991F8-2595-48D8-9F74-609A388C2D84Q28278684-B2325320-4CD2-4529-B6A8-1967697B6E5EQ33614231-2F1950AA-9903-4133-8AC9-2DB8315E2D94Q34492381-45E1FFE5-4325-4A09-AEF2-14347C9A8F05Q34547274-F17A032C-FF56-41EA-8C31-41458139A031Q34549390-680042E5-8039-4CD6-A0D8-EB0A27BB814BQ35682184-456EF748-DE11-4A6E-AEE2-175DC0AECD2AQ35822283-253FF208-AF37-4488-B4F9-B686E625719AQ36002723-E9758B40-2067-4E1C-9B86-21BF4BE4DD05Q36273782-20425782-7251-468C-9787-07D356DEF993Q37490388-AEB81D32-F637-4F1E-9BEB-4CBFEFEF20A7Q37547285-F3CDECC5-6633-475C-8B7C-3FA640C13B8FQ37662689-0372B33D-B03A-4949-856F-286A6F5F2A4EQ38211107-F8D507CB-4C0B-48B8-B9BB-51D09EA1DEB4Q38685420-5AEF6A4A-9ECE-4D96-B5B1-8755D6BC4B3AQ38692317-715510F4-1EE4-431B-B9CC-3EE3BF91AC12Q38743867-1B54F93C-ACAE-44FC-B1FC-BB1C5CD76697Q38791739-C1097B0C-9A9E-4635-8CEE-333DB9FB0720Q38793772-F24FAFE0-0BD7-46BC-B44E-6C72CFB9F13FQ39008886-4BF76C10-50F5-4794-BC2D-C0BFCE6CB2ECQ39067664-38B97B0E-84CB-4425-A8F7-7B648ABCBF7CQ39659622-FEC1455D-5CE2-43DD-82ED-2A9F1F072C6EQ42315149-B5B79BE3-3832-4428-8675-748BE72655DBQ42650304-3D803710-05FE-4011-AD18-39E2B25AA29BQ46237980-4E7E2C4C-1EDC-4289-AAF8-C084F2EEF563Q46259903-54F9988B-2844-4322-8939-84245F545E0DQ47107894-9E5D4528-5DEF-4233-A458-D448C22D8736Q47151084-0A7A50BB-89CC-478F-939C-5C1C6830E9E2Q47306135-1132FBEB-FF44-437C-AF4D-FBF137222FEEQ47403269-1B4DBC9A-A0B5-4D26-BA22-AF1C823897B8Q47421692-34154DDF-60E5-43E2-B9E0-5017C6907A51Q47425773-B0E302F3-8502-4530-8544-ABB7060448E7Q47572680-D894B185-18D2-4189-82E9-75F90528BF8CQ47572684-924D99A8-40AC-4CE4-904B-23F096259C94
P2860
R (-)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
R (-)-ketamine shows greater p ...... nt effects than S (+)-ketamine
@ast
R (-)-ketamine shows greater p ...... nt effects than S (+)-ketamine
@en
R (-)-ketamine shows greater p ...... nt effects than S (+)-ketamine
@nl
type
label
R (-)-ketamine shows greater p ...... nt effects than S (+)-ketamine
@ast
R (-)-ketamine shows greater p ...... nt effects than S (+)-ketamine
@en
R (-)-ketamine shows greater p ...... nt effects than S (+)-ketamine
@nl
prefLabel
R (-)-ketamine shows greater p ...... nt effects than S (+)-ketamine
@ast
R (-)-ketamine shows greater p ...... nt effects than S (+)-ketamine
@en
R (-)-ketamine shows greater p ...... nt effects than S (+)-ketamine
@nl
P3181
P1476
R (-)-ketamine shows greater p ...... nt effects than S (+)-ketamine
@en
P2093
Ji-Chun Zhang
P304
P3181
P356
10.1016/J.PBB.2013.11.033
P407
P50
P577
2014-01-01T00:00:00Z