The tumor suppressor maspin does not undergo the stressed to relaxed transition or inhibit trypsin-like serine proteases. Evidence that maspin is not a protease inhibitory serpin
about
The ovalbumin serpins revisited: perspective from the chicken genome of clade B serpin evolution in vertebratesMaspin: the new frontierMolecular cloning of bomapin (protease inhibitor 10), a novel human serpin that is expressed specifically in the bone marrowMaspin inhibits cell migration in the absence of protease inhibitory activityEvidence for a direct interaction between the tumor suppressor serpin, maspin, and types I and III collagenHuman cytoplasmic antiproteinase neutralizes rapidly and efficiently chymotrypsin and trypsin-like proteases utilizing distinct reactive site residuesIdentification and characterization of a novel rat ov-serpin family member, trespinHaploinsufficiency of the maspin tumor suppressor gene leads to hyperplastic lesions in prostateTumor-suppressive maspin regulates cell response to oxidative stress by direct interaction with glutathione S-transferase.Maspin suppresses survival of lung cancer cells through modulation of Akt pathway.Role of myoepithelial cells in breast tumor progression.Maspin--a novel protease inhibitor with tumor-suppressing activity in breast cancer.Maspin regulates endothelial cell adhesion and migration through an integrin signaling pathway.Purification, cDNA cloning, and characterization of a new serpin with megakaryocyte maturation activity.SERPINB11 is a new noninhibitory intracellular serpin. Common single nucleotide polymorphisms in the scaffold impair conformational change.Identification of phosphorylation sites on extracellular corneal epithelial cell maspinIdentification of an intrinsic determinant critical for maspin subcellular localization and function.Nuclear location of tumor suppressor protein maspin inhibits proliferation of breast cancer cells without affecting proliferation of normal epithelial cells.Tissue-type plasminogen activator is a target of the tumor suppressor gene maspin.Simultaneous evaluation of maspin and CXCR4 in patients with breast cancer.Maspin reprograms the gene expression profile of prostate carcinoma cells for differentiation.mMaspin: the mouse homolog of a human tumor suppressor gene inhibits mammary tumor invasion and motilityCancer proteomics by quantitative shotgun proteomics.Epigenetic silencing of maspin expression occurs early in the conversion of keratocytes to fibroblasts.Role of maspin in cancer.HDAC1 inhibition by maspin abrogates epigenetic silencing of glutathione S-transferase pi in prostate carcinoma cells.Serpins in T cell immunity.Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells.An emerging role for the nuclear localization of maspin in the suppression of tumor progression and metastasis.Maspin: molecular mechanisms and therapeutic implications.TAp63gamma can substitute for p53 in inducing expression of the maspin tumor suppressor.Sufficiency of the reactive site loop of maspin for induction of cell-matrix adhesion and inhibition of cell invasion. Conversion of ovalbumin to a maspin-like molecule.Decline in the expression of the serine proteinase inhibitor maspin is associated with tumour progression in ductal carcinomas of the breast.Identification of Serpinb6b as a species-specific mouse granzyme A inhibitor suggests functional divergence between human and mouse granzyme A.Polymerization of human angiotensinogen: insights into its structural mechanism and functional significanceMaspin is a deoxycholate-inducible, anti-apoptotic stress-response protein differentially expressed during colon carcinogenesis.Loss of maspin expression contributes to a more invasive potential in malignant melanoma.Epigenetic status and aberrant expression of the maspin gene in human hepato-biliary tract carcinomas.Loop variants of the serpin thyroxine-binding globulin: implications for hormone release upon limited proteolysis.A novel function of tissue factor pathway inhibitor-2 (TFPI-2) in human glioma invasion.
P2860
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P2860
The tumor suppressor maspin does not undergo the stressed to relaxed transition or inhibit trypsin-like serine proteases. Evidence that maspin is not a protease inhibitory serpin
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The tumor suppressor maspin do ...... t a protease inhibitory serpin
@ast
The tumor suppressor maspin do ...... t a protease inhibitory serpin
@en
The tumor suppressor maspin do ...... t a protease inhibitory serpin
@nl
type
label
The tumor suppressor maspin do ...... t a protease inhibitory serpin
@ast
The tumor suppressor maspin do ...... t a protease inhibitory serpin
@en
The tumor suppressor maspin do ...... t a protease inhibitory serpin
@nl
prefLabel
The tumor suppressor maspin do ...... t a protease inhibitory serpin
@ast
The tumor suppressor maspin do ...... t a protease inhibitory serpin
@en
The tumor suppressor maspin do ...... t a protease inhibitory serpin
@nl
P2093
P356
P1476
The tumor suppressor maspin do ...... t a protease inhibitory serpin
@en
P2093
H L Gibson
M C Kiefer
P A Fitzpatrick
P A Pemberton
P304
P356
10.1074/JBC.270.26.15832
P407
P577
1995-06-30T00:00:00Z