Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site
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The Role of Crk Adaptor Proteins in T-Cell Adhesion and MigrationThe adaptor protein Crk in immune responseDomain organization differences explain Bcr-Abl's preference for CrkL over CrkIICharacterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and DeathInterplay of the proto-oncogene proteins CrkL and CrkII in insulin-like growth factor-I receptor-mediated signal transductionPSTPIP 2, a second tyrosine phosphorylated, cytoskeletal-associated protein that binds a PEST-type protein-tyrosine phosphataseAbl family kinases regulate FcγR-mediated phagocytosis in murine macrophagesCyclophilin A promotes cell migration via the Abl-Crk signaling pathway.Iterative tyrosine phosphorylation controls non-canonical domain utilization in Crk.Avian influenza viruses inhibit the major cellular signalling integrator c-Abl.Phosphorylation of Dok1 by Abl family kinases inhibits CrkI transforming activity.CrkL mediates Ras-dependent activation of the Raf/ERK pathway through the guanine nucleotide exchange factor C3G in hematopoietic cells stimulated with erythropoietin or interleukin-3.Involvement of the adapter protein CRKL in integrin-mediated adhesion.Structural requirements for function of the Crkl adapter protein in fibroblasts and hematopoietic cells.The non-receptor tyrosine kinase Lyn controls neutrophil adhesion by recruiting the CrkL-C3G complex and activating Rap1 at the leading edgeCRK proteins selectively regulate T cell migration into inflamed tissues.A bead-based activity screen for small-molecule inhibitors of signal transduction in chronic myelogenous leukemia cells.Subcellular distribution of p210(BCR-ABL) in CML cell lines and primary CD34+ CML cells.Protein kinase substrate identification on functional protein arraysPhotocleavable peptide-oligonucleotide conjugates for protein kinase assays by MALDI-TOF MSContribution of Crk adaptor proteins to host cell and bacteria interactions.Odin (ANKS1A) is a Src family kinase target in colorectal cancer cells.GILZ inhibits the mTORC2/AKT pathway in BCR-ABL(+) cells.Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer.Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers.Assaying Bcr-Abl kinase activity and inhibition in whole cell extracts by phosphorylation of substrates immobilized on agarose beads.The WAVE2 complex regulates T cell receptor signaling to integrins via Abl- and CrkL-C3G-mediated activation of Rap1.Tyrosine phosphorylation of the nuclear receptor coactivator AIB1/SRC-3 is enhanced by Abl kinase and is required for its activity in cancer cells.High CC chemokine receptor 7 expression improves postoperative prognosis of lung adenocarcinoma patientsEscherichia coli virulence protein NleH1 interaction with the v-Crk sarcoma virus CT10 oncogene-like protein (CRKL) governs NleH1 inhibition of the ribosomal protein S3 (RPS3)/nuclear factor κB (NF-κB) pathway.Acute dasatinib exposure commits Bcr-Abl-dependent cells to apoptosis.BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia.Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases.Aberrant signalling by protein kinase CK2 in imatinib-resistant chronic myeloid leukaemia cells: biochemical evidence and therapeutic perspectives.The level of BCR-ABL1 kinase activity before treatment does not identify chronic myeloid leukemia patients who fail to achieve a complete cytogenetic response on imatinibA specific need for CRKL in p210BCR-ABL-induced transformation of mouse hematopoietic progenitors.BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl.Analysis of Cellular Tyrosine Phosphorylation via Chemical Rescue of Conditionally Active Abl Kinase.MPT0B002, a novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells.Inhibition of 32Dp210 cells harboring T315I mutation by a novel derivative of emodin correlates with down-regulation of BCR-ABL and its downstream signaling pathways.
P2860
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P2860
Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site
description
1997 nî lūn-bûn
@nan
1997 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site
@ast
Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site
@en
Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site
@nl
type
label
Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site
@ast
Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site
@en
Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site
@nl
prefLabel
Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site
@ast
Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site
@en
Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site
@nl
P2093
P356
P1433
P1476
Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site
@en
P2093
J ten Hoeve
N Heisterkamp
P2888
P304
P356
10.1038/SJ.ONC.1200885
P407
P577
1997-02-06T00:00:00Z
P5875
P6179
1002413829