Substrate-specific activation of sirtuins by resveratrol
about
A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in miceDietary, metabolic, and potentially environmental modulation of the lysine acetylation machineryIncreased life span due to calorie restriction in respiratory-deficient yeastNegative regulation of the deacetylase SIRT1 by DBC1Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cellsRapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous miceLessons on longevity from budding yeastResveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterasesResveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTORThe prolongevity effect of resveratrol depends on dietary composition and calorie intake in a tephritid fruit flySIRT1 activation by small molecules: kinetic and biophysical evidence for direct interaction of enzyme and activatorSRT1720 improves survival and healthspan of obese miceSRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1Biochemical effects of SIRT1 activatorsSirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stressHormonal control of androgen receptor function through SIRT1Regulation of the Telomerase Reverse Transcriptase Subunit through Epigenetic MechanismsSirtuin functions and modulation: from chemistry to the clinicFinding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging MoleculesResveratrol and MyopathyPotential Modulation of Sirtuins by Oxidative StressSirt1 and the MitochondriaNatural Products as Tools for Defining How Cellular Metabolism Influences Cellular Immune and Inflammatory Function during Chronic InfectionBiochemical Genetic Pathways that Modulate Aging in Multiple SpeciesAn Organ System Approach to Explore the Antioxidative, Anti-Inflammatory, and Cytoprotective Actions of ResveratrolProperties of Resveratrol: In Vitro and In Vivo Studies about Metabolism, Bioavailability, and Biological Effects in Animal Models and HumansStructural basis for sirtuin activity and inhibitionHistone modifications and a choice of variant: a language that helps the genome express itselfEpigenomics of leukemia: from mechanisms to therapeutic applicationsSirtuin 1 and sirtuin 3: physiological modulators of metabolismThe controversial world of sirtuinsMolecular turnover, the H3.3 dilemma and organismal aging (hypothesis)Targeting sirtuin 1 to improve metabolism: all you need is NAD(+)?The role of mammalian sirtuins in the regulation of metabolism, aging, and longevityLysine deacetylase (KDAC) regulatory pathways: an alternative approach to selective modulationModulation of tumorigenesis by dietary intervention is not mediated by SIRT1 catalytic activityResveratrol Directly Binds to Mitochondrial Complex I and Increases Oxidative Stress in Brain Mitochondria of Aged MiceA Molecular Mechanism for Direct Sirtuin Activation by ResveratrolEx-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanismPotential of Natural Products in the Inhibition of Adipogenesis through Regulation of PPARγ Expression and/or Its Transcriptional Activity
P2860
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P2860
Substrate-specific activation of sirtuins by resveratrol
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Substrate-specific activation of sirtuins by resveratrol
@ast
Substrate-specific activation of sirtuins by resveratrol
@en
Substrate-specific activation of sirtuins by resveratrol
@nl
type
label
Substrate-specific activation of sirtuins by resveratrol
@ast
Substrate-specific activation of sirtuins by resveratrol
@en
Substrate-specific activation of sirtuins by resveratrol
@nl
prefLabel
Substrate-specific activation of sirtuins by resveratrol
@ast
Substrate-specific activation of sirtuins by resveratrol
@en
Substrate-specific activation of sirtuins by resveratrol
@nl
P2093
P3181
P356
P1476
Substrate-specific activation of sirtuins by resveratrol
@en
P2093
Andrew Napper
Antonio Bedalov
Birgit Heltweg
Brian K Kennedy
Eric A Westman
Jeffrey Hixon
Peter S DiStefano
Rory Curtis
Seth D Caldwell
Stanley Fields
P304
P3181
P356
10.1074/JBC.M500655200
P407
P577
2005-04-29T00:00:00Z