Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor - Wikidata - awgldk - TriplyDB

Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor

Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor

http://www.wikidata.org/entity/Q28305618

about

Dopamine D3 and D2 receptor mechanisms in the abuse-related behavioral effects of cocaine: studies with preferential antagonists in squirrel monkeys Lack of abuse potential in a highly selective dopamine D3 agonist, PF-592,379, in drug self-administration and drug discrimination in rats Design, synthesis, and evaluation of potent and selective ligands for the dopamine 3 (D3) receptor with a novel in vivo behavioral profile N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists Analogues of the dopamine D2 receptor antagonist L741,626: Binding, function, and SAR Differential effects of the dopamine D3 receptor antagonist PG01037 on cocaine and methamphetamine self-administration in rhesus monkeys Dopamine D3 Receptor Antagonists as Potential Therapeutics for the Treatment of Neurological Diseases.Pharmacological actions of NGB 2904, a selective dopamine D3 receptor antagonist, in animal models of drug addiction Beyond small-molecule SAR: using the dopamine D3 receptor crystal structure to guide drug design Phenylpiperazine derivatives with selectivity for dopamine D3 receptors modulate cocaine self-administration in rats A series of 18F-labelled pyridinylphenyl amides as subtype-selective radioligands for the dopamine D3 receptor.Dopamine D3 receptors mediate the discriminative stimulus effects of quinpirole in free-feeding rats.Subtype selectivity of dopamine receptor ligands: insights from structure and ligand-based methods Dopamine D(3) receptors contribute to methamphetamine-induced alterations in dopaminergic neuronal function: role of hyperthermia.Dopaminergic regulation of dopamine D3 and D3nf receptor mRNA expression Dopamine agonist-induced yawning in rats: a dopamine D3 receptor-mediated behavior.The dopamine D3 receptor partial agonist CJB090 and antagonist PG01037 decrease progressive ratio responding for methamphetamine in rats with extended-access.Design, synthesis, and structure-activity relationship studies of a series of [4-(4-carboxamidobutyl)]-1-arylpiperazines: insights into structural features contributing to dopamine D3 versus D2 receptor subtype selectivity.Synthesis and characterization of selective dopamine D2 receptor antagonists. 2. Azaindole, benzofuran, and benzothiophene analogs of L-741,626.Dopamine D1 and D3 receptors mediate reconsolidation of cocaine memories in mouse models of drug self-administration Tranylcypromine substituted cis-hydroxycyclobutylnaphthamides as potent and selective dopamine D₃ receptor antagonists.Targeting the dopamine D3 receptor: an overview of drug design strategies.Influence of cocaine history on the behavioral effects of Dopamine D(3) receptor-selective compounds in monkeys.Yawning and hypothermia in rats: effects of dopamine D3 and D2 agonists and antagonists.N-(3-fluoro-4-(4-(2-methoxy or 2,3-dichlorophenyl)piperazine-1-yl)butyl)arylcarboxamides as selective dopamine D3 receptor ligands: critical role of the carboxamide linker for D3 receptor selectivity.Yawning and locomotor behavior induced by dopamine receptor agonists in mice and rats.Discovery, optimization, and characterization of novel D2 dopamine receptor selective antagonists.Synthesis and characterization of selective dopamine D₂ receptor ligands using aripiprazole as the lead compound Effects of selective dopaminergic compounds on a delay-discounting task.Current perspectives on selective dopamine D(3) receptor antagonists as pharmacotherapeutics for addictions and related disorders.Structure-activity relationships for a novel series of dopamine D2-like receptor ligands based on N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ol.Dopamine receptors and Parkinson's disease Investigation of the binding and functional properties of extended length D3 dopamine receptor-selective antagonists C57BL/6J mice exhibit reduced dopamine D3 receptor-mediated locomotor-inhibitory function relative to DBA/2J mice Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis.Drinking sucrose or saccharin enhances sensitivity of rats to quinpirole-induced yawning High-affinity and selective dopamine D₃ receptor full agonists Comparison of the binding and functional properties of two structurally different D2 dopamine receptor subtype selective compounds.Cocaine self-administration in dopamine D₃ receptor knockout mice.Dopamine D3 receptors regulate reconsolidation of cocaine memory.

P2860

Q24598398-C27BCCAD-8243-499F-84A9-1F6A913F2F6A Q24614563-B299EA9D-4711-4884-97E9-E381BF64556B Q24651049-979C74A0-9C1D-446C-BA75-E386A6D60939 Q24653995-0FFED476-703B-4607-8CA9-BAE5A21338D5 Q24683864-B60D70AE-FA88-45F0-8B7F-540E665857D4 Q27305163-AE4B2ADC-B393-441F-8F0E-9D022144F174 Q28067056-817F9853-1DEC-4CB0-8804-0B604AC58D92 Q28236375-8DE3C29A-B365-43B8-B967-A37BB3B40764 Q28828620-765C2652-5281-4308-A5A6-7C94BD54DC10 Q30581703-74E926C7-B33A-4F3B-B874-CE6DF10CCED7 Q33560926-C49D9253-BC96-4F96-8AD4-3929E4575310 Q33574910-DF431E16-6004-4027-BEEE-1CB7F63BE7D3 Q33615741-A434E829-E7BE-440C-AFFC-4A1FB2D90120 Q33768609-03562203-6380-4877-B1F1-22BCE71CEA90 Q33926442-EA7B0053-972D-4445-978C-0D85543D199D Q33947433-ABC3E11F-62F2-455C-B043-6018EF99968D Q33992366-7258CC63-B960-45B6-AA42-6C41B33BE4EB Q34104379-1957CA15-0148-4DA1-8C24-0696C1DCA6F3 Q34158231-47E77EFB-A6FD-458B-BFD4-500521E65962 Q34231896-A75486D8-299D-4C2C-A4E8-582316682900 Q34435684-88D4BBB1-DF4F-401D-98F8-51228E2C4EE6 Q34524556-F5147DD9-D1AD-4DE3-BE00-1D2EFB64A878 Q34762698-0F976A14-595B-44F6-A4D3-95B44822AD2B Q34982537-31D23EB1-CA1C-467A-AEFD-E4A4CC79EDC3 Q35001217-32DD970D-7729-4729-87D7-07E768AD9472 Q35010070-A4D2ACC9-BD2D-4023-907A-CB390C60CA54 Q35043389-54AD3968-C158-4A81-AC1B-1A671407A513 Q35055114-64A48E7B-AD32-4A3A-B86E-EE6E1EDF1070 Q35103242-213E8C84-1E71-4230-A046-8EC224788C78 Q35143623-45DEFFCD-2525-4786-9622-EB576CF3D71D Q35168503-C418815F-967A-4BEE-9A87-92A7E1A19E8E Q35545020-5351C1DB-D280-437E-BBD2-395D2DAF142D Q35666067-6D8414CB-0C03-48E5-84DB-43719488117F Q35669949-0A465F88-4083-4D42-97B0-5845A6710EF8 Q35892818-BCFE9779-5BAF-4EA9-B06D-8F2D0CEF6F87 Q36144895-A8776017-6781-498F-9393-3359CDE434C3 Q36288428-A8CC3DE5-00AD-49F5-B1D1-3432619FB995 Q36479708-7BC139A6-238A-4489-B358-079A4DCC2697 Q36655271-731620AF-2F55-43E3-9A6C-3DB5914B205A Q36823743-18C603D6-54F3-41A5-88B7-B0F4BD06038F

P2860

Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor

http://www.wikidata.org/entity/Q28305618

description

2005 nî lūn-bûn

@nan

2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Novel heterocyclic trans olefi ...... y for the dopamine D3 receptor

@ast

Novel heterocyclic trans olefi ...... y for the dopamine D3 receptor

@en

Novel heterocyclic trans olefi ...... y for the dopamine D3 receptor

@nl

type

label

Novel heterocyclic trans olefi ...... y for the dopamine D3 receptor

@ast

Novel heterocyclic trans olefi ...... y for the dopamine D3 receptor

@en

Novel heterocyclic trans olefi ...... y for the dopamine D3 receptor

@nl

prefLabel

Novel heterocyclic trans olefi ...... y for the dopamine D3 receptor

@ast

Novel heterocyclic trans olefi ...... y for the dopamine D3 receptor

@en

Novel heterocyclic trans olefi ...... y for the dopamine D3 receptor

@nl

P1433

Q28305618-7AFB98B6-DC8F-4903-BDAC-8E665A8341BA

P1476

Q28305618-FAE13CAA-876F-4BD0-AFC7-D77E7B99DD1E

P2093

Q28305618-2DC2737A-A957-4D4D-AEDD-D99919857242

Q28305618-3088938B-B2B9-4F0F-BD6C-D3686ACD0C88

Q28305618-42BBA6B1-E82C-429F-B140-57117B61AF54

Q28305618-6BC410DA-6229-44B6-90D8-2D9FB1ADD482

Q28305618-A9D121FF-B960-4386-ACC1-572579927DAB

Q28305618-B6052087-A234-486E-BBDC-F5884570CE77

Q28305618-D9FAEBEF-AC61-4126-9496-136B29C08757

P304

Q28305618-4FFE1FDC-33A4-46F6-9A5C-899AA05BF52B

P31

Q28305618-AEFFC45D-D19F-4458-ABF8-F7539ED46D08

P3181

Q28305618-E123FA06-2500-427E-87B3-601BFB1123A7

P356

Q28305618-206AA50F-0261-4776-8D77-C42CA4E70FA4

P407

Q28305618-3BABA904-7772-4DA2-8E85-1C8F297BB926

P433

Q28305618-EA24F5FE-89BF-42A2-8B89-B31F1180C68D

P478

Q28305618-870EE6FD-2D6B-4705-82C7-A615FB56647B

P50

Q28305618-89658641-B134-4ADB-933E-1858B4B9EDB8

P577

Q28305618-3A565421-4A79-4532-A66B-91586D085CD3

P698

Q28305618-06F4AFFC-5775-4546-8C01-EEA6F0878B27

P921

Q28305618-a017ffe8-b25e-47e5-92f7-f0d48152da82

P3181

P356

P1433

Journal of Medicinal Chemistry

P1476

Novel heterocyclic trans olefi ...... y for the dopamine D3 receptor

@en

P2093

Christina J Bennett

http://www.w3.org/2001/XMLSchema#string

Elizabeth McElveen

http://www.w3.org/2001/XMLSchema#string

Erin E Carlson

http://www.w3.org/2001/XMLSchema#string

Jianjing Cao

http://www.w3.org/2001/XMLSchema#string

Michelle Taylor

http://www.w3.org/2001/XMLSchema#string

Peter Grundt

http://www.w3.org/2001/XMLSchema#string

Robert R Luedtke

http://www.w3.org/2001/XMLSchema#string

P304

839-48

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

3129468

http://www.w3.org/2001/XMLSchema#string

P356

10.1021/JM049465G

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

48

http://www.w3.org/2001/XMLSchema#string

P50

Amy Hauck Newman

P577

2005-02-10T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

15689168

http://www.w3.org/2001/XMLSchema#string

P921