Challenges in the search for drugs to treat central nervous system disorders
about
Linked clinical trials--the development of new clinical learning studies in Parkinson's disease using screening of multiple prospective new treatmentsInhibition of microglia activation as a phenotypic assay in early drug discoveryThe GABAβ receptor as a target for antidepressant drug actionA system for performing high throughput assays of synaptic functionUsing Drugs as Molecular Probes: A Computational Chemical Biology Approach in Neurodegenerative DiseasesCurrent approaches for the discovery of drugs that deter substance and drug abuse.From basic to clinical neuropharmacology: targetophilia or pharmacodynamics?Modeling resilience to schizophrenia in genetically modified mice: a novel approach to drug discovery.Using NMR approaches to drive the search for new CNS therapeutics.Discovering novel neuroactive drugs through high-throughput behavior-based chemical screening in the zebrafish.Extrasynaptic site of action for γ-hydroxybutyrate.Fire in the ashes: can failed Alzheimer's disease drugs succeed with second chances?Emerging cognitive enhancing drugs.Clinical trials in rare disease: challenges and opportunities.Comments on the working group's 2012 review of the Program.Multitarget ligands and theranostics: sharpening the medicinal chemistry sword against prion diseases.Studying human disease using human neurons.Improving Current Treatments for Schizophrenia.The seeming paradox of adenosine receptors as targets for the treatment of Alzheimer's disease: agonists or antagonists?Translational neuropharmacology and the appropriate and effective use of animal models.Obesity Drug Update: The Lost Decade?Dendrimers in combination with natural products and analogues as anti-cancer agents.Phenotypic drug screening.Brain activity patterns in high-throughput electrophysiology screen predict both drug efficacies and side effects.The role of fMRI in drug development.In Situ-Based Gels for Nose to Brain Delivery for the Treatment of Neurological Diseases.Predicting the activity and toxicity of new psychoactive substances: a pharmaceutical industry perspective.PhenotypicIn VivoScreening to Identify New, Unpredicted Indications for Existing Drugs and Drug Candidates
P2860
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P2860
Challenges in the search for drugs to treat central nervous system disorders
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Challenges in the search for drugs to treat central nervous system disorders
@ast
Challenges in the search for drugs to treat central nervous system disorders
@en
Challenges in the search for drugs to treat central nervous system disorders
@nl
type
label
Challenges in the search for drugs to treat central nervous system disorders
@ast
Challenges in the search for drugs to treat central nervous system disorders
@en
Challenges in the search for drugs to treat central nervous system disorders
@nl
prefLabel
Challenges in the search for drugs to treat central nervous system disorders
@ast
Challenges in the search for drugs to treat central nervous system disorders
@en
Challenges in the search for drugs to treat central nervous system disorders
@nl
P356
P1476
Challenges in the search for drugs to treat central nervous system disorders
@en
P2093
P304
P356
10.1124/JPET.108.143420
P407
P577
2009-05-01T00:00:00Z