Aryl phosphate derivatives of AZT retain activity against HIV1 in cell lines which are resistant to the action of AZT

Aryl phosphate derivatives of AZT retain activity against HIV1 in cell lines which are resistant to the action of AZT

Item
http://www.wikidata.org/entity/Q28321177
Synthesis of nucleoside phosphate and phosphonate prodrugsSynthesis of dual function (5R,6R)- and (5S,6S)-5-bromo-6-methoxy-5,6-dihydro-AZT-5'-(para-bromophenyl methoxyalaninyl phosphate) as novel spermicidal and anti-HIV agentsAZT-5'-(p-bromophenyl methoxyalaninyl phosphate) as a potent and non-toxic anti-human immunodeficiency virus agentSynthesis and antiviral activity of aryl phosphoramidate derivatives of beta-D- and beta-L-C-5-substituted 2',3'-didehydro-2',3'-dideoxy-uridine bearing linker arms.Pronucleotides: toward the in vivo delivery of antiviral and anticancer nucleotides.Progress in the development of anti-hepatitis C virus nucleoside and nucleotide prodrugs.Design, synthesis and antiviral evaluation of 2'-C-methyl branched guanosine pronucleotides: the discovery of IDX184, a potent liver-targeted HCV polymerase inhibitor.β-l-1-[5-(E-2-bromovinyl)-2-(hydroxymethyl)-1,3-(dioxolan-4-yl)] uracil (l-BHDU) prevents varicella-zoster virus replication in a SCID-Hu mouse model and does not interfere with 5-fluorouracil catabolism.Synthesis and biological evaluation of 2',3'-didehydro-2',3'-dideoxy-9-deazaguanosine, a monophosphate prodrug and two analogues, 2',3'-dideoxy-9-deazaguanosine and 2',3'-didehydro-2',3'-dideoxy-9-deazainosine.Bis-ketol nucleoside triesters as prodrugs of the antiviral nucleoside triphosphate analogues of 3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine.Pro-nucleotide inhibitors of adenylyl cyclases in intact cells.The ProTides Boom.Nucleoside analogues previously found to be inactive against HIV may be activated by simple chemical phosphorylation.Certain phosphoramidate derivatives of dideoxy uridine (ddU) are active against HIV and successfully by-pass thymidine kinase.Synthesis and anti-herpetic activity of phosphoramidate ProTides.Synthesis and anti-HIV activity of carbamates of antiviral agent stavudine.Synthesis of Oligonucleotide Conjugates and Phosphorylated Nucleotide Analogues: An Improvement to a Solid Phase Synthetic Approach
P2860

Aryl phosphate derivatives of AZT retain activity against HIV1 in cell lines which are resistant to the action of AZT

Item
http://www.wikidata.org/entity/Q28321177
description
1992 nî lūn-bûn
@nan
1992 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Aryl phosphate derivatives of ...... resistant to the action of AZT
@ast
Aryl phosphate derivatives of ...... resistant to the action of AZT
@en
Aryl phosphate derivatives of ...... resistant to the action of AZT
@nl
type
label
Aryl phosphate derivatives of ...... resistant to the action of AZT
@ast
Aryl phosphate derivatives of ...... resistant to the action of AZT
@en
Aryl phosphate derivatives of ...... resistant to the action of AZT
@nl
prefLabel
Aryl phosphate derivatives of ...... resistant to the action of AZT
@ast
Aryl phosphate derivatives of ...... resistant to the action of AZT
@en
Aryl phosphate derivatives of ...... resistant to the action of AZT
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Aryl phosphate derivatives of ...... resistant to the action of AZT
@en
P2093
P304
P31
P356
10.1016/0166-3542(92)90026-2
P407
P433
P478
P577
P698