Human immunodeficiency virus reverse transcriptase. Substrate and inhibitor kinetics with thymidine 5'-triphosphate and 3'-azido-3'-deoxythymidine 5'-triphosphate
about
Role of helix P of the human cytomegalovirus DNA polymerase in resistance and hypersusceptibility to the antiviral drug foscarnet.PCR amplification of DNA containing non-standard base pairs by variants of reverse transcriptase from Human Immunodeficiency Virus-1Structural basis for activation of α-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptasePolycitone A, a novel and potent general inhibitor of retroviral reverse transcriptases and cellular DNA polymerases5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83), a selective anti-human immunodeficiency virus agent with an improved metabolic and toxicological profileMechanism of resistance of human immunodeficiency virus type 1 to 2',3'-dideoxyinosineThe 5'-triphosphates of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolane-5-yl]cytosine equally inhibit human immunodeficiency virus type 1 reverse transcriptaseMode of inhibition of HIV reverse transcriptase by 2-hexaprenylhydroquinone, a novel general inhibitor of RNA-and DNA-directed DNA polymerasesInhibition of multiple phases of human immunodeficiency virus type 1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteinsHuman immunodeficiency virus reverse transcriptase substitutes for DNA polymerase I in Escherichia coli.The effects of nucleoside analogs on telomerase and telomeres in Tetrahymena.A cell-based strategy to assess intrinsic inhibition efficiencies of HIV-1 reverse transcriptase inhibitors.Mechanisms of nucleoside analog antiviral activity and resistance during human immunodeficiency virus reverse transcriptionEffects of 3'-deoxynucleoside 5'-triphosphate concentrations on chain termination by nucleoside analogs during human immunodeficiency virus type 1 reverse transcription of minus-strand strong-stop DNAHuman immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesisThe DNA polymerase gamma Y955C disease variant associated with PEO and parkinsonism mediates the incorporation and translesion synthesis opposite 7,8-dihydro-8-oxo-2'-deoxyguanosine.Binding of RNA template to a complex of HIV-1 reverse transcriptase/primer/templateAntiviral peptide nanocomplexes as a potential therapeutic modality for HIV/HCV co-infection.Development of an optimized dose for coformulation of zidovudine with drugs that select for the K65R mutation using a population pharmacokinetic and enzyme kinetic simulation model.Nucleotide incorporation by human DNA polymerase gamma opposite benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyguanosine and deoxyadenosine.Regulation of the reverse transcriptase of human immunodeficiency virus type 1 by dNTPs.Disease mutations in the human mitochondrial DNA polymerase thumb subdomain impart severe defects in mitochondrial DNA replication.Simultaneous quantification of 9-(beta-D-1,3-dioxolan-4-yl)guanine, Amdoxovir and Zidovudine in human plasma by liquid chromatography-tandem mass spectrometric assaySubstrate inhibition of the human immunodeficiency virus type 1 reverse transcriptase.Site-specific crosslinking of 4-thiouridine-modified human tRNA(3Lys) to reverse transcriptase from human immunodeficiency virus type I.3'-azido-3'-deoxythymidine (AZT) monophosphate: an inhibitor of exonucleolytic repair of AZT-terminated DNAEffects of zidovudine-selected human immunodeficiency virus type 1 reverse transcriptase amino acid substitutions on processive DNA synthesis and viral replication.Increased polymerase fidelity of E89G, a nucleoside analog-resistant variant of human immunodeficiency virus type 1 reverse transcriptase.Steady state kinetics and inhibition of HIV-1 reverse transcriptase by a non-nucleoside dipyridodiazepinone, BI-RG-587, using a heteropolymeric template.Sequence-specific DNA primer effects on telomerase polymerization activity.Nano-NRTIs: efficient inhibitors of HIV type-1 in macrophages with a reduced mitochondrial toxicity.
P2860
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P2860
Human immunodeficiency virus reverse transcriptase. Substrate and inhibitor kinetics with thymidine 5'-triphosphate and 3'-azido-3'-deoxythymidine 5'-triphosphate
description
1990 nî lūn-bûn
@nan
1990 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Human immunodeficiency virus r ...... deoxythymidine 5'-triphosphate
@ast
Human immunodeficiency virus r ...... deoxythymidine 5'-triphosphate
@en
Human immunodeficiency virus r ...... deoxythymidine 5'-triphosphate
@nl
type
label
Human immunodeficiency virus r ...... deoxythymidine 5'-triphosphate
@ast
Human immunodeficiency virus r ...... deoxythymidine 5'-triphosphate
@en
Human immunodeficiency virus r ...... deoxythymidine 5'-triphosphate
@nl
prefLabel
Human immunodeficiency virus r ...... deoxythymidine 5'-triphosphate
@ast
Human immunodeficiency virus r ...... deoxythymidine 5'-triphosphate
@en
Human immunodeficiency virus r ...... deoxythymidine 5'-triphosphate
@nl
P1476
Human immunodeficiency virus r ...... deoxythymidine 5'-triphosphate
@en
P2093
J E Reardon
W H Miller
P304
P407
P577
1990-11-25T00:00:00Z