The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C
about
VEGF stimulates RCAN1.4 expression in endothelial cells via a pathway requiring Ca2+/calcineurin and protein kinase C-deltaThe phospholipase C/protein kinase C pathway is involved in cathepsin G-induced human platelet activation: comparison with thrombinRas activation in platelets after stimulation of the thrombin receptor, thromboxane A2 receptor or protein kinase CProteinase-activated receptor-2 mediated inhibition of TNFalpha-stimulated JNK activation - A novel paradigm for G(q/11) linked GPCRsTyrosine phosphorylation of an SH2-containing protein tyrosine phosphatase is coupled to platelet thrombin receptor via a pertussis toxin-sensitive heterotrimeric G-proteinThe Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cellsReceptor protein tyrosine phosphatase alpha participates in the m1 muscarinic acetylcholine receptor-dependent regulation of Kv1.2 channel activityPhosphorylation and activation of mitogen- and stress-activated protein kinase-1 in adult rat cardiac myocytes by G-protein-coupled receptor agonists requires both extracellular-signal-regulated kinase and p38 mitogen-activated protein kinaseRetinoic acid receptors inhibit AP1 activation by regulating extracellular signal-regulated kinase and CBP recruitment to an AP1-responsive promoter.Activation of classical protein kinase C reduces the expression of human cationic amino acid transporter 3 (hCAT-3) in the plasma membraneCharacterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growthCa2+-dependent rapid Ca2+ sensitization of contraction in arterial smooth muscleIdentification of SRPK1 and SRPK2 as the major cellular protein kinases phosphorylating hepatitis B virus core proteinThe metabotropic glutamate receptor 4 is internalized and desensitized upon protein kinase C activationExtracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytesUse of mRNA- and protein-destabilizing elements to develop a highly responsive reporter systemPhorbol myristate acetate and Bryostatin 1 rescue IFN-gamma inducibility of MHC class II molecules in LS1034 colorectal carcinoma cell linePhorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of KATP channelsMultiple phosphorylation events control mitotic degradation of the muscle transcription factor Myf5.Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATPBuilding bridges toward invasion: tumor promoter treatment induces a novel protein kinase C-dependent phenotype in MCF10A mammary cell aciniFacilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancementThe NS5A/NS5 proteins of viruses from three genera of the family flaviviridae are phosphorylated by associated serine/threonine kinasesPhosphorylation of the hepatitis C virus NS5A protein in vitro and in vivo: properties of the NS5A-associated kinaseTyrosine phosphorylation of paxillin and focal adhesion kinase by activation of muscarinic m3 receptors is dependent on integrin engagement by the extracellular matrixProstaglandin E2 and the protein kinase A pathway mediate arachidonic acid induction of c-fos in human prostate cancer cellsProtein kinase C delta and eta isoenzymes control the shedding of the interleukin 6 receptor alpha in myeloma cellsProtein kinase inhibitors can suppress stress-induced dissociation of Hsp27Vascular endothelial growth factor-induced prostacyclin production is mediated by a protein kinase C (PKC)-dependent activation of extracellular signal-regulated protein kinases 1 and 2 involving PKC-delta and by mobilization of intracellular Ca2+Phosphorylation of RGS9-1 by an endogenous protein kinase in rod outer segments.Involvement of the ERK mitogen-activated protein kinase in cell resistance to complement-mediated lysisCharacterization of the MN/CA 9 promoter proximal region: a role for specificity protein (SP) and activator protein 1 (AP1) factorsThrombin-induced p38 mitogen-activated protein kinase activation is mediated by epidermal growth factor receptor transactivation pathwayACh-induced rebound stimulation of L-type Ca(2+) current in guinea-pig ventricular myocytes, mediated by Gbetagamma-dependent activation of adenylyl cyclaseIn rat hepatocytes, the hypertonic activation of Na(+) conductance and Na(+)-K(+)-2Cl(-) symport--but not Na(+)-H(+) antiport--is mediated by protein kinase CRegulation of VEGF-induced endothelial cell PAF synthesis: role of p42/44 MAPK, p38 MAPK and PI3K pathwaysEarly decrease in respiration and uncoupling event independent of cytochrome C release in PC12 cells undergoing apoptosisPKCalpha regulates platelet granule secretion and thrombus formation in miceIncreased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenaseRear polarization of the microtubule-organizing center in neointimal smooth muscle cells depends on PKCα, ARPC5, and RHAMM
P2860
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P2860
The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C
description
1991 nî lūn-bûn
@nan
1991 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
The bisindolylmaleimide GF 109 ...... inhibitor of protein kinase C
@ast
The bisindolylmaleimide GF 109 ...... inhibitor of protein kinase C
@en
The bisindolylmaleimide GF 109 ...... inhibitor of protein kinase C
@nl
type
label
The bisindolylmaleimide GF 109 ...... inhibitor of protein kinase C
@ast
The bisindolylmaleimide GF 109 ...... inhibitor of protein kinase C
@en
The bisindolylmaleimide GF 109 ...... inhibitor of protein kinase C
@nl
prefLabel
The bisindolylmaleimide GF 109 ...... inhibitor of protein kinase C
@ast
The bisindolylmaleimide GF 109 ...... inhibitor of protein kinase C
@en
The bisindolylmaleimide GF 109 ...... inhibitor of protein kinase C
@nl
P2093
P3181
P1476
The bisindolylmaleimide GF 109 ...... inhibitor of protein kinase C
@en
P2093
E Boursier
F Loriolle
P Bellevergue
P Pianetti
T Grand-Perret
P304
15771-15781
P3181
P407
P577
1991-08-01T00:00:00Z