Analogues of 1,5-bis(4-amidinophenoxy)pentane (pentamidine) in the treatment of experimental Pneumocystis carinii pneumonia
about
Pentamidine binds to tRNA through non-specific hydrophobic interactions and inhibits aminoacylation and translationDesigner DNA-binding drugs: the crystal structure of a meta-hydroxy analogue of Hoechst 33258 bound to d(CGCGAATTCGCG)2Treatment of experimental pneumocystosis: review of 7 years of experience and development of a new system for classifying antimicrobial drugsStructure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensisInhibition of Cryptosporidium parvum in neonatal Hsd:(ICR)BR Swiss miceby polyether ionophores and aromatic amidinesNovel pentamidine analogs in the treatment of experimental Pneumocystis carinii pneumoniaEffects of atovaquone and other inhibitors on Pneumocystis carinii dihydroorotate dehydrogenaseGuanylhydrazones in therapy of Pneumocystis carinii pneumonia in immunosuppressed rats.Structure-in vitro activity relationships of pentamidine analogues and dication-substituted bis-benzimidazoles as new antifungal agentsIn vitro antifungal activities of a series of dication-substituted carbazoles, furans, and benzimidazolesComparative efficacy evaluation of dicationic carbazole compounds, nitazoxanide, and paromomycin against Cryptosporidium parvum infections in a neonatal mouse model.Activity of cationically substituted bis-benzimidazoles against experimental Pneumocystis carinii pneumoniaAnti-Pneumocystis activities of aromatic diamidoxime prodrugs.Biological Efficacy and Toxicity of Diamidines in Myotonic Dystrophy Type 1 Models.Molecular characterization of recombinant Pneumocystis carinii topoisomerase I: differential interactions with human topoisomerase I poisons and pentamidine.Structure-activity relationships of pentamidine analogs against Giardia lamblia and correlation of antigiardial activity with DNA-binding affinity.Reducing levels of toxic RNA with small moleculesArylimidamide DB766, a potential chemotherapeutic candidate for Chagas' disease treatmentCharacterization of a novel DNA minor-groove complex.In vitro selection and in vivo efficacy of piperazine- and alkanediamide-linked bisbenzamidines against Pneumocystis pneumonia in mice.Metabolic N-hydroxylation of pentamidine in vitro.Synthesis of N-substituted aryl amidines by strong base activation of amines.In vitro and in vivo antifungal activities of T-2307, a novel arylamidine.Activity of pentamidine and pentamidine analogs against Toxoplasma gondii in cell cultures.Pentamidine analogs as inhibitors of [(3)H]MK-801 and [(3)H]ifenprodil binding to rat brain NMDA receptors.Diamidines versus Monoamidines as Anti-Pneumocystis Agents: An in Vivo Study.Neglected disease - african sleeping sickness: recent synthetic and modeling advances.The dependence of DNase I activity on the conformation of oligodeoxynucleotides.Anti-Pneumocystis carinii pneumonia activity of dicationic 2,4-diarylpyrimidines.Hexamidine salts - applications in skin health and personal care products.Structure-activity relationships of pentamidine-affected ion channel trafficking and dofetilide mediated rescue.Pentamidine inhibits catalytic activity of group I intron Ca.LSU by altering RNA folding.Polyamide curvature and DNA sequence selective recognition: use of 4-aminobenzamide to adjust curvature.Sequence-selective binding to DNA of bis(amidinophenoxy)alkanes related to propamidine and pentamidine.Pentamidine Congeners 1: Synthesis of Cis- and Trans-Butamidine Analogues As Anti-Pneumocystis carinii Pneumonia Agents.Understanding the DNA binding of novel non-symmetrical guanidinium/2-aminoimidazolinium derivatives.Synthesis of dicationic diaryltriazines nucleic acid binding agents.Reversible Self-Assembled Monolayers (rSAMs): Adaptable Surfaces for Enhanced Multivalent Interactions and Ultrasensitive Virus Detection.Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors.Efficient and specific cardiac IK₁ inhibition by a new pentamidine analogue.
P2860
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P2860
Analogues of 1,5-bis(4-amidinophenoxy)pentane (pentamidine) in the treatment of experimental Pneumocystis carinii pneumonia
description
1990 nî lūn-bûn
@nan
1990 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Analogues of 1,5-bis(4-amidino ...... Pneumocystis carinii pneumonia
@ast
Analogues of 1,5-bis(4-amidino ...... Pneumocystis carinii pneumonia
@en
Analogues of 1,5-bis(4-amidino ...... Pneumocystis carinii pneumonia
@nl
type
label
Analogues of 1,5-bis(4-amidino ...... Pneumocystis carinii pneumonia
@ast
Analogues of 1,5-bis(4-amidino ...... Pneumocystis carinii pneumonia
@en
Analogues of 1,5-bis(4-amidino ...... Pneumocystis carinii pneumonia
@nl
prefLabel
Analogues of 1,5-bis(4-amidino ...... Pneumocystis carinii pneumonia
@ast
Analogues of 1,5-bis(4-amidino ...... Pneumocystis carinii pneumonia
@en
Analogues of 1,5-bis(4-amidino ...... Pneumocystis carinii pneumonia
@nl
P2093
P356
P1476
Analogues of 1,5-bis(4-amidino ...... Pneumocystis carinii pneumonia
@en
P2093
P304
P356
10.1021/JM00166A026
P407
P577
1990-04-01T00:00:00Z