Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation
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NMR Solution Structure, Stability, and Interaction of the Recombinant Bovine Fibrinogen αC-Domain Fragment †Integrin conformational regulation: uncoupling extension/tail separation from changes in the head region by a multiresolution approach.Binding strength and activation state of single fibrinogen-integrin pairs on living cells.Integrin alphaIIbbeta3:ligand interactions are linked to binding-site remodeling.Structure, stability, and interaction of the fibrin(ogen) alphaC-domainsRecreation of the terminal events in physiological integrin activation.Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand.Dynamic regulation of fibrinogen: integrin αIIbβ3 binding.Identification of integrin beta subunit mutations that alter heterodimer function in situ.PROBING αIIbβ3: LIGAND INTERACTIONS BY DYNAMIC FORCE SPECTROSCOPY AND SURFACE PLASMON RESONANCE.Affinity, lateral mobility, and clustering contribute independently to beta 2-integrin-mediated adhesion.Avidity modulation activates adhesion under flow and requires cooperativity among adhesion receptors.High affinity ligand binding by integrins does not involve head separation.Solution properties of full-length integrin alpha(IIb)beta3 refined models suggest environment-dependent induction of alternative bent /extended resting states.Ligand binding promotes the entropy-driven oligomerization of integrin alpha IIb beta 3.Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis.Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions.
P2860
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P2860
Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation
@ast
Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation
@en
Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation
@nl
type
label
Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation
@ast
Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation
@en
Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation
@nl
prefLabel
Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation
@ast
Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation
@en
Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation
@nl
P2093
P2860
P356
P1433
P1476
Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation
@en
P2093
C Nagaswami
J W Weisel
R R Hantgan
P2860
P304
P356
10.1110/PS.3001
P407
P50
P577
2001-08-01T00:00:00Z