Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins)
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Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatinModulation of the expression of connective tissue growth factor by alterations of the cytoskeleton.Lovastatin Inhibits Low Molecular Weight Hyaluronan Induced Chemokine Expression via LFA-1 and Decreases Bleomycin-Induced Pulmonary Fibrosis.Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways.The role of connective tissue growth factor (CTGF/CCN2) in skeletogenesis.Connective tissue growth factor: a role in airway remodelling in asthma?Beneficial Effects of Statins on the Rates of Hepatic Fibrosis, Hepatic Decompensation, and Mortality in Chronic Liver Disease: A Systematic Review and Meta-Analysis.Fibrogenesis in Crohn's disease.Lysophosphatidic acid and renal fibrosis.Effect of statins on disease-related outcomes in patients with idiopathic pulmonary fibrosis.Pharmacological strategies to spare normal tissues from radiation damage: useless or overlooked therapeutics?G protein-coupled receptors: bridging the gap from the extracellular signals to the Hippo pathway.Rac1-mediated cardiac damage causes diastolic dysfunction in a mouse model of subacute doxorubicin-induced cardiotoxicity.Statins Reduce the Risk of Cirrhosis and Its Decompensation in Chronic Hepatitis B Patients: A Nationwide Cohort Study.Statins in anthracycline-induced cardiotoxicity: Rac and Rho, and the heartbreakers.Protective effect of statin therapy on connective tissue growth factor induction by diabetes in vivo and high glucose in vitro.Transforming growth factor-beta1 (TGFbeta1) stimulates connective tissue growth factor (CCN2/CTGF) expression in human gingival fibroblasts through a RhoA-independent, Rac1/Cdc42-dependent mechanism: statins with forskolin block TGFbeta1-induced CCNInhibitory effect of statins on renal epithelial-to-mesenchymal transition.Protection of adult mouse progenitor cells and human glioma cells by de novo decorin expression in an oxygen- and glucose-deprived cell culture model system.Local Application of Statins Significantly Reduced Hypertrophic Scarring in a Rabbit Ear Model.Simvastatin ameliorates low-dose streptozotocin-induced type 2 diabetic nephropathy in an experimental rat model.Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-β in human tubular epithelial cells.Statins and the risk of cirrhosis in hepatitis B or C patients: a systematic review and dose-response meta-analysis of observational studies.Strategies for blocking the fibrogenic actions of connective tissue growth factor (CCN2): From pharmacological inhibition in vitro to targeted siRNA therapy in vivo.A Phase II Study to Prevent Radiation-induced Rectal Injury With Lovastatin.Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia.Simvastatin inhibits transforming growth factor-β1-induced expression of type I collagen, CTGF, and α-SMA in keloid fibroblasts.Measurement of liver collagen synthesis by heavy water labeling: effects of profibrotic toxicants and antifibrotic interventions.In vitro inhibitory effects of atorvastatin on cardiac fibroblasts: implications for ventricular remodelling.The small GTPase Rac-1 is a regulator of mesangial cell morphology and thrombospondin-1 expression.Effects of simvastatin on pulmonary fibrosis, pulmonary hypertension and exercise capacity in bleomycin-treated rats.Rosuvastatin ameliorates high-fat and high-cholesterol diet-induced nonalcoholic steatohepatitis in rats.Cyclical cell stretching of skin-derived fibroblasts downregulates connective tissue growth factor (CTGF) production.
P2860
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P2860
Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins)
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Rho-dependent inhibition of th ...... reductase inhibitors (statins)
@ast
Rho-dependent inhibition of th ...... reductase inhibitors (statins)
@en
Rho-dependent inhibition of th ...... reductase inhibitors (statins)
@nl
type
label
Rho-dependent inhibition of th ...... reductase inhibitors (statins)
@ast
Rho-dependent inhibition of th ...... reductase inhibitors (statins)
@en
Rho-dependent inhibition of th ...... reductase inhibitors (statins)
@nl
prefLabel
Rho-dependent inhibition of th ...... reductase inhibitors (statins)
@ast
Rho-dependent inhibition of th ...... reductase inhibitors (statins)
@en
Rho-dependent inhibition of th ...... reductase inhibitors (statins)
@nl
P2860
P356
P1476
Rho-dependent inhibition of th ...... reductase inhibitors (statins)
@en
P2093
J Heusinger-Ribeiro
M Goppelt-Struebe
P2860
P304
P356
10.1038/SJ.BJP.0704173
P407
P577
2001-08-01T00:00:00Z