Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance - Wikidata - awgldk - TriplyDB

Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance

Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance

http://www.wikidata.org/entity/Q28346563

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A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep Brain circuits regulating energy homeostasis Identification and characterization of a melanin-concentrating hormone receptor Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R Lateral hypothalamic circuits for feeding and reward Deep Brain Stimulation for Obesity Obesity pharmacotherapy: current perspectives and future directions Brain regulation of energy balance and body weight.Brain Regulation of Energy Metabolism Neurons containing orexin or melanin concentrating hormone reciprocally regulate wake and sleep Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone.The role of melanin-concentrating hormone and its receptors in energy homeostasis Tubby is required for trafficking G protein-coupled receptors to neuronal cilia Predictive models of glucose control: roles for glucose-sensing neurones.Forebrain networks and the control of feeding by environmental learned cues.Periplakin interferes with G protein activation by the melanin-concentrating hormone receptor-1 by binding to the proximal segment of the receptor C-terminal tail.High-throughput screening of novel antagonists on melanin-concentrating hormone receptor-1.The pharmacological properties of a novel MCH1 receptor antagonist isolated from combinatorial libraries.The Melanin-Concentrating Hormone as an Integrative Peptide Driving Motivated Behaviors Meta-analysis of melanin-concentrating hormone signaling-deficient mice on behavioral and metabolic phenotypes A comparative analysis shows morphofunctional differences between the rat and mouse melanin-concentrating hormone systems.Chronic loss of melanin-concentrating hormone affects motivational aspects of feeding in the rat The role of melanin concentrating hormone (MCH) in the central chemoreflex: a knockdown study by siRNA in the lateral hypothalamus in rats.Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist.Role of melanin-concentrating hormone in the control of ethanol consumption: Region-specific effects revealed by expression and injection studies Does the melanin-concentrating hormone antagonist SNAP-7941 deserve 3As?Melanin-concentrating hormone functions in the nervous system: food intake and stress.Evaluation of AMG 076, a potent and selective MCHR1 antagonist, in rodent and primate obesity models Animals models of MCH function and what they can tell us about its role in energy balance Melanin-concentrating hormone receptor mutations and human obesity: functional analysis.Identification and characterization of single-nucleotide polymorphisms in MCH-R1 and MCH-R2.Profiling the interaction mechanism of quinoline/quinazoline derivatives as MCHR1 antagonists: an in silico method.Two naturally occurring mutations in the type 1 melanin-concentrating hormone receptor abolish agonist-induced signaling.Further insights into the neurobiology of melanin-concentrating hormone in energy and mood balances.Spleen-derived interleukin-10 downregulates the severity of high-fat diet-induced non-alcoholic fatty pancreas disease Tuberal hypothalamic neurons secreting the satiety molecule Nesfatin-1 are critically involved in paradoxical (REM) sleep homeostasis.To ingest or rest? Specialized roles of lateral hypothalamic area neurons in coordinating energy balance.Melanin-concentrating hormone and its receptors: state of the art.

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P2860

Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance

http://www.wikidata.org/entity/Q28346563

description

2001 nî lūn-bûn

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2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2001 թվականի փետրվարին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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name

Melanin-concentrating hormone ...... obesity and insulin resistance

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Melanin-concentrating hormone ...... obesity and insulin resistance

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Melanin-concentrating hormone ...... obesity and insulin resistance

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type

label

Melanin-concentrating hormone ...... obesity and insulin resistance

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Melanin-concentrating hormone ...... obesity and insulin resistance

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Melanin-concentrating hormone ...... obesity and insulin resistance

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prefLabel

Melanin-concentrating hormone ...... obesity and insulin resistance

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Melanin-concentrating hormone ...... obesity and insulin resistance

@en

Melanin-concentrating hormone ...... obesity and insulin resistance

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Journal of Clinical Investigation

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Melanin-concentrating hormone ...... obesity and insulin resistance

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B Lowell

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E Kokkotou

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E Maratos-Flier

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J Elmquist

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J S Flier

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J W Mastaitis

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N A Tritos

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R Kulkarni

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P2860

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

Obesity and the hypothalamus: novel peptides for new pathways

The melanin-concentrating hormone system of the rat brain: an immuno- and hybridization histochemical characterization

Targeted disruption of the melanocortin-4 receptor results in obesity in mice

Two important systems in energy homeostasis: melanocortins and melanin-concentrating hormone.

Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines.

Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action.

Mice lacking melanin-concentrating hormone are hypophagic and lean.

Correction of obesity and diabetes in genetically obese mice by leptin gene therapy.

Characterization of expression of hypothalamic appetite-regulating peptides in obese hyperleptinemic brown adipose tissue-deficient (uncoupling protein-promoter-driven diphtheria toxin A) mice.

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379-386

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10.1172/JCI10660

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