PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis
about
Triptolide in the treatment of psoriasis and other immune-mediated inflammatory diseasesImmunosuppressive, anti-inflammatory and anti-cancer properties of triptolide: A mini reviewIdentification of triptolide, a natural diterpenoid compound, as an inhibitor of lung inflammation.Tumor necrosis factor-α accelerates the resolution of established pulmonary fibrosis in mice by targeting profibrotic lung macrophages.Role of myofibroblasts at the invasion front.IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosisRole of tissue stroma in cancer cell invasion.A critical role for the mTORC2 pathway in lung fibrosis.Triptolide ameliorates colonic fibrosis in an experimental rat modelNatural products to drugs: natural product derived compounds in clinical trials.Mitogen-activated protein kinase phosphatase-1 modulates regional effects of injurious mechanical ventilation in rodent lungs.Non-invasive Imaging of Idiopathic Pulmonary Fibrosis Using Cathepsin Protease Probes.Development and assessment of countermeasure formulations for treatment of lung injury induced by chlorine inhalationThe bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?Triptolide mitigates radiation-induced pulmonary fibrosis via inhibition of axis of alveolar macrophages-NOXes-ROS-myofibroblasts.How useful is traditional herbal medicine for pulmonary fibrosis?Immunosuppressant discovery from Tripterygium wilfordii Hook f: the novel triptolide analog (5R)-5-hydroxytriptolide (LLDT-8)Tripterygium wilfordii bioactive compounds as anticancer and anti-inflammatory agents.Antifibrotic effects of triptolide on hepatic stellate cells and dimethylnitrosamine-intoxicated rats.Triptolide inhibits extracellular matrix protein synthesis by suppressing the Smad2 but not the MAPK pathway in TGF-beta1-stimulated NRK-49F cells.Bleomycin-induced pulmonary fibrosis is attenuated by an antibody against KL-6.Triptolide attenuates endotoxin- and staphylococcal exotoxin-induced T-cell proliferation and production of cytokines and chemokines.Mechanism of triptolide-induced apoptosis: Effect on caspase activation and Bid cleavage and essentiality of the hydroxyl group of triptolide.Triptolide attenuates renal interstitial fibrosis in rats with unilateral ureteral obstruction.Triptolide inhibits TGF-β1 induced proliferation and migration of rat airway smooth muscle cells by suppressing NF-κB but not ERK1/2.Efficacy and Safety of Endoscopic Balloon Dilation for Upper Gastrointestinal Strictures of Crohn's Disease.Triptolide suppresses IL-1beta-induced chemokine and stromelysin-1 gene expression in human colonic subepithelial myofibroblasts.A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F.
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P2860
PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis
@ast
PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis
@en
PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis
@nl
type
label
PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis
@ast
PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis
@en
PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis
@nl
prefLabel
PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis
@ast
PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis
@en
PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis
@nl
P2093
P2860
P1476
PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis
@en
P2093
P2860
P304
P356
10.1016/S0002-9440(10)64046-1
P407
P577
2001-03-01T00:00:00Z