Tonabersat (SB-220453) a novel benzopyran with anticonvulsant properties attenuates trigeminal nerve-induced neurovascular reflexes - Wikidata - awgldk - TriplyDB

Tonabersat (SB-220453) a novel benzopyran with anticonvulsant properties attenuates trigeminal nerve-induced neurovascular reflexes

Tonabersat (SB-220453) a novel benzopyran with anticonvulsant properties attenuates trigeminal nerve-induced neurovascular reflexes

http://www.wikidata.org/entity/Q28361230

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Molecular targets for antiepileptic drug development Tonabersat inhibits trigeminal ganglion neuronal-satellite glial cell signaling.Neurological mechanisms of migraine: potential of the gap-junction modulator tonabersat in prevention of migraine.Emerging drugs in migraine treatment.Can we develop neurally acting drugs for the treatment of migraine?New drugs for migraine Migraine: emerging treatment options for preventive and acute attack therapy.Tonabersat, a novel gap-junction modulator for the prevention of migraine.Involvement of gap junction channels in the pathophysiology of migraine with aura.New and investigational antiepileptic drugs.Efficacy and mechanism of anticonvulsant drugs in migraine.Influence of drugs on gap junctions in glioma cell lines and primary astrocytes in vitro.Efficacy and safety of tonabersat, a gap-junction modulator, in the acute treatment of migraine: a double-blind, parallel-group, randomized study.A double-blind study of SB-220453 (Tonerbasat) in the glyceryltrinitrate (GTN) model of migraine.[In the pipeline. Triptans--new developments].Randomized, double-blind, placebo-controlled, proof-of-concept study of the cortical spreading depression inhibiting agent tonabersat in migraine prophylaxis.Side effects associated with current and prospective antimigraine pharmacotherapies.Tonabersat Prevents Inflammatory Damage in the Central Nervous System by Blocking Connexin43 Hemichannels.

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Tonabersat (SB-220453) a novel benzopyran with anticonvulsant properties attenuates trigeminal nerve-induced neurovascular reflexes

http://www.wikidata.org/entity/Q28361230

description

2001 nî lūn-bûn

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2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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Tonabersat (SB-220453) a novel ...... induced neurovascular reflexes

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Tonabersat (SB-220453) a novel ...... induced neurovascular reflexes

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British Journal of Pharmacology

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Tonabersat (SB-220453) a novel ...... induced neurovascular reflexes

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A A Parsons

http://www.w3.org/2001/XMLSchema#string

M Thompson

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N Upton

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P2860

Vasoactive peptide release in the extracerebral circulation of humans during migraine headache

Human in vivo evidence for trigeminovascular activation in cluster headache. Neuropeptide changes and effects of acute attacks therapies

SB-220453, a potential novel antimigraine agent, inhibits nitric oxide release following induction of cortical spreading depression in the anaesthetized cat.

The trigeminovascular system in humans: pathophysiologic implications for primary headache syndromes of the neural influences on the cerebral circulation.

Nonepileptic uses of gabapentin.

Benzo[b]pyranols and related novel antiepileptic agents.

A review of paroxysmal hemicranias, SUNCT syndrome and other short-lasting headaches with autonomic feature, including new cases.

Profile of SB-204269, a mechanistically novel anticonvulsant drug, in rat models of focal and generalized epileptic seizures.

Peripheral GABAA receptor-mediated effects of sodium valproate on dural plasma protein extravasation to substance P and trigeminal stimulation

The antimigraine drug, sumatriptan (GR43175), selectively blocks neurogenic plasma extravasation from blood vessels in dura mater

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10.1038/SJ.BJP.0703932

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11264249

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1572685

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