Nuclear translocation controlled by alternatively spliced isoforms inactivates the QUAKING apoptotic inducer - Wikidata - awgldk - TriplyDB

Nuclear translocation controlled by alternatively spliced isoforms inactivates the QUAKING apoptotic inducer

Nuclear translocation controlled by alternatively spliced isoforms inactivates the QUAKING apoptotic inducer

http://www.wikidata.org/entity/Q28362265

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Kep1 interacts genetically with dredd/caspase-8, and kep1 mutants alter the balance of dredd isoforms Unusual intron conservation near tissue-regulated exons found by splicing microarrays.Emerging functions of the Quaking RNA-binding proteins and link to human diseases Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression.Structural Analysis of the Quaking Homodimerization Interface RNA binding protein QKI inhibits the ischemia/reperfusion-induced apoptosis in neonatal cardiomyocytes The QKI-6 RNA binding protein regulates actin-interacting protein-1 mRNA stability during oligodendrocyte differentiation.Quaking is essential for blood vessel development KHDC1B is a novel CPEB binding partner specifically expressed in mouse oocytes and early embryos Viral infection, inflammation and schizophrenia Impaired cytoskeletal organization and membrane integrity in lens fibers of a Rho GTPase functional knockout transgenic mouse.The QKI-6 and QKI-7 RNA binding proteins block proliferation and promote Schwann cell myelination.Genome analysis: RNA recognition motif (RRM) and K homology (KH) domain RNA-binding proteins from the flowering plant Arabidopsis thaliana.The small 11 kDa nonstructural protein of human parvovirus B19 plays a key role in inducing apoptosis during B19 virus infection of primary erythroid progenitor cells.Overexpression of miR-29a reduces the oncogenic properties of glioblastoma stem cells by downregulating Quaking gene isoform 6 The QKI-6 RNA binding protein localizes with the MBP mRNAs in stress granules of glial cells RNA-binding protein quaking, a critical regulator of colon epithelial differentiation and a suppressor of colon cancer.Expression of Hqk encoding a KH RNA binding protein is altered in human glioma.KHDC1A, a novel translational repressor, induces endoplasmic reticulum-dependent apoptosis Evolutionary Dynamics of GLD-1-mRNA complexes in Caenorhabditis nematodes.Tumor microenvironment-associated modifications of alternative splicing.Gene regulation at the RNA layer: RNA binding proteins in intercellular signaling networks.Loss of p53 in quaking viable mice leads to Purkinje cell defects and reduced survival.Expression of Quaking RNA-Binding Protein in the Adult and Developing Mouse Retina.miR-574-5p negatively regulates Qki6/7 to impact β-catenin/Wnt signalling and the development of colorectal cancer.Reproductive and neurological Quaking(viable) phenotypes in a severe combined immune deficient mouse background MicroRNA-214 Promotes Dendritic Development by Targeting the Schizophrenia-associated Gene Quaking (Qki).MiR-143-3p functions as a tumor suppressor by regulating cell proliferation, invasion and epithelial-mesenchymal transition by targeting QKI-5 in esophageal squamous cell carcinoma.Essential function, sophisticated regulation and pathological impact of the selective RNA-binding protein QKI in CNS myelin development.Target RNA motif and target mRNAs of the Quaking STAR protein.Intracellular Protein Shuttling: A Mechanism Relevant for Myelin Repair in Multiple Sclerosis?RNA-binding protein QKI-5 inhibits the proliferation of clear cell renal cell carcinoma via post-transcriptional stabilization of RASA1 mRNA Preparation and characterizations of polyclonal antibodies against STAR protein QKI7b.The QKI-5 and QKI-6 RNA binding proteins regulate the expression of microRNA 7 in glial cells.Tyrosine phosphorylation of QKI mediates developmental signals to regulate mRNA metabolism.Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression.Quaking and miR-155 interactions in inflammation and leukemogenesis.Transcriptome profiling of mouse brains with qkI-deficient oligodendrocytes reveals major alternative splicing defects including self-splicing.Gene Expression of Quaking in Sporadic Alzheimer's Disease Patients is Both Upregulated and Related to Expression Levels of Genes Involved in Amyloid Plaque and Neurofibrillary Tangle Formation.Identification of Sam68 arginine glycine-rich sequences capable of conferring nonspecific RNA binding to the GSG domain.

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P2860

Nuclear translocation controlled by alternatively spliced isoforms inactivates the QUAKING apoptotic inducer

http://www.wikidata.org/entity/Q28362265

description

2001 nî lūn-bûn

@nan

2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Nuclear translocation controll ...... the QUAKING apoptotic inducer

@ast

Nuclear translocation controll ...... the QUAKING apoptotic inducer

@en

Nuclear translocation controll ...... the QUAKING apoptotic inducer

@nl

type

label

Nuclear translocation controll ...... the QUAKING apoptotic inducer

@ast

Nuclear translocation controll ...... the QUAKING apoptotic inducer

@en

Nuclear translocation controll ...... the QUAKING apoptotic inducer

@nl

prefLabel

Nuclear translocation controll ...... the QUAKING apoptotic inducer

@ast

Nuclear translocation controll ...... the QUAKING apoptotic inducer

@en

Nuclear translocation controll ...... the QUAKING apoptotic inducer

@nl

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Genes & Development

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Nuclear translocation controll ...... the QUAKING apoptotic inducer

@en

P2093

D Larocque

http://www.w3.org/2001/XMLSchema#string

J Pilotte

http://www.w3.org/2001/XMLSchema#string

S Richard

http://www.w3.org/2001/XMLSchema#string

P2860

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

Cloning and expression of four novel isoforms of human interleukin-1 beta converting enzyme with different apoptotic activities

Structure-function analysis of Qk1: a lethal point mutation in mouse quaking prevents homodimerization.

MCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-M

Self-association of the single-KH-domain family members Sam68, GRP33, GLD-1, and Qk1: role of the KH domain

The STAR protein QKI-6 is a translational repressor

The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein

Death receptors: signaling and modulation

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

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845-58

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scholarly article

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389615

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10.1101/GAD.860301

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7

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15

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11297509

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apoptotic process

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312664

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