Mechanism of rhodopsin activation as examined with ring-constrained retinal analogs and the crystal structure of the ground state protein
about
Signaling states of rhodopsin. Formation of the storage form, metarhodopsin III, from active metarhodopsin IINovel RDH12 mutations associated with Leber congenital amaurosis and cone-rod dystrophy: biochemical and clinical evaluationsMolecular dynamics investigation of primary photoinduced events in the activation of rhodopsin.Photoactivation-induced instability of rhodopsin mutants T4K and T17M in rod outer segments underlies retinal degeneration in X. laevis transgenic models of retinitis pigmentosaLigand channeling within a G-protein-coupled receptor. The entry and exit of retinals in native opsin.Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosaBiochemical and physiological properties of rhodopsin regenerated with 11-cis-6-ring- and 7-ring-retinalsG protein-coupled receptor rhodopsin: a prospectus.Conformational changes of G protein-coupled receptors during their activation by agonist binding.Structural analysis and dynamics of retinal chromophore in dark and meta I states of rhodopsin from 2H NMR of aligned membranes.Retinal dynamics during light activation of rhodopsin revealed by solid-state NMR spectroscopy.Photocyclic behavior of rhodopsin induced by an atypical isomerization mechanism.Complex binding pathways determine the regeneration of mammalian green cone opsin with a locked retinal analogue.Stress tensor analysis of the protein quake of photoactive yellow protein.Signaling states of rhodopsin: absorption of light in active metarhodopsin II generates an all-trans-retinal bound inactive state.A nonbleachable rhodopsin analogue with a slow photocycle.Rhodopsin with 11-cis-locked chromophore is capable of forming an active state photoproduct.Critical role of transmembrane segment zinc binding in the structure and function of rhodopsin.Transition of rhodopsin into the active metarhodopsin II state opens a new light-induced pathway linked to Schiff base isomerization.Retinal-chitosan conjugates effectively deliver active chromophores to retinal photoreceptor cells in blind mice and dogs.
P2860
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P2860
Mechanism of rhodopsin activation as examined with ring-constrained retinal analogs and the crystal structure of the ground state protein
description
2001 nî lūn-bûn
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2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
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2001年の論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年论文
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name
Mechanism of rhodopsin activat ...... re of the ground state protein
@ast
Mechanism of rhodopsin activat ...... re of the ground state protein
@en
Mechanism of rhodopsin activat ...... re of the ground state protein
@nl
type
label
Mechanism of rhodopsin activat ...... re of the ground state protein
@ast
Mechanism of rhodopsin activat ...... re of the ground state protein
@en
Mechanism of rhodopsin activat ...... re of the ground state protein
@nl
prefLabel
Mechanism of rhodopsin activat ...... re of the ground state protein
@ast
Mechanism of rhodopsin activat ...... re of the ground state protein
@en
Mechanism of rhodopsin activat ...... re of the ground state protein
@nl
P2093
P2860
P921
P356
P1476
Mechanism of rhodopsin activat ...... re of the ground state protein
@en
P2093
K P Hofmann
K Palczewski
P2860
P304
26148-26153
P356
10.1074/JBC.M102212200
P407
P577
2001-04-20T00:00:00Z