MDR1 causes resistance to the antitumour drug miltefosine - Wikidata - awgldk - TriplyDB

MDR1 causes resistance to the antitumour drug miltefosine

MDR1 causes resistance to the antitumour drug miltefosine

http://www.wikidata.org/entity/Q28365282

about

Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis Imipramine is an orally active drug against both antimony sensitive and resistant Leishmania donovani clinical isolates in experimental infection P-glycoprotein (ABCB1) interacts directly with lipid-based anti-cancer drugs and platelet-activating factors.Genomic and Molecular Characterization of Miltefosine Resistance in Leishmania infantum Strains with Either Natural or Acquired Resistance through Experimental Selection of Intracellular Amastigotes.Functional Validation of ABCA3 as a Miltefosine Transporter in Human Macrophages: IMPACT ON INTRACELLULAR SURVIVAL OF LEISHMANIA (VIANNIA) PANAMENSIS.Complex Interplay between the P-Glycoprotein Multidrug Efflux Pump and the Membrane: Its Role in Modulating Protein Function.Leishmania donovani resistance to miltefosine involves a defective inward translocation of the drug.Effects of a detergent micelle environment on P-glycoprotein (ABCB1)-ligand interactions.Functional study of intracellular P-gp- and MRP1-mediated pumping of free cytosolic pirarubicin into acidic organelles in intrinsic resistant SiHa cells.

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P2860

MDR1 causes resistance to the antitumour drug miltefosine

http://www.wikidata.org/entity/Q28365282

description

2001 nî lūn-bûn

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2001 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2001 թվականի մայիսին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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MDR1 causes resistance to the antitumour drug miltefosine

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MDR1 causes resistance to the antitumour drug miltefosine

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MDR1 causes resistance to the antitumour drug miltefosine

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MDR1 causes resistance to the antitumour drug miltefosine

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MDR1 causes resistance to the antitumour drug miltefosine

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MDR1 causes resistance to the antitumour drug miltefosine

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MDR1 causes resistance to the antitumour drug miltefosine

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British Journal of Cancer

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A D Pietro

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F J Sharom

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J Hofmann

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P Lu

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R Liu

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P2860

A multidrug resistance transporter from human MCF-7 breast cancer cells

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

The drug resistance-related protein LRP is the human major vault protein

Biochemistry of multidrug resistance mediated by the multidrug transporter

Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone. Evidence for a third drug-binding site.

Spectroscopic and biophysical approaches for studying the structure and function of the P-glycoprotein multidrug transporter.

Insights into the structure and substrate interactions of the P-glycoprotein multidrug transporter from spectroscopic studies.

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction

Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185----Val-185 substitution in P-glycoprotein.

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