Sigma opiates and certain antipsychotic drugs mutually inhibit (+)-[3H] SKF 10,047 and [3H]haloperidol binding in guinea pig brain membranes
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Targeting sigma receptors: novel medication development for drug abuse and addictionAn unambiguous assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and a distinct structure-affinity relationship for butyrophenones1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugsDifferentiation of sigma ligand-activated receptor subtypes that modulate NMDA-evoked [3H]-noradrenaline release in rat hippocampal slicesStereoselective action of (+)-morphine over (-)-morphine in attenuating the (-)-morphine-produced antinociception via the naloxone-sensitive sigma receptor in the mouse4-aroylpiperidines and 4-(α-hydroxyphenyl)piperidines as selective sigma-1 receptor ligands: synthesis, preliminary pharmacological evaluation and computational studiesEffects of (+)-pentazocine and 1,3-di-o-tolylguanidine (DTG), sigma (sigma) ligands, on micturition in anaesthetized rats.Identification of the binding subunit of the sigma-type opiate receptor by photoaffinity labeling with 1-(4-azido-2-methyl[6-3H]phenyl)-3-(2-methyl[4,6-3H]phenyl)guanidine.The σ2 receptor: a novel protein for the imaging and treatment of cancer.Current hypotheses on sigma receptors and their physiological role: possible implications in psychiatry.Reviewing the ketamine model for schizophrenia.The sigma-1 receptor chaperone as an inter-organelle signaling modulatorNeurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus.Roles of sigma-1 receptors in Alzheimer's disease.The attenuation of learning impairments induced after exposure to CO or trimethyltin in mice by sigma (sigma) receptor ligands involves both sigma1 and sigma2 sitesPregnancy reduces brain sigma receptor function.Intrathecal treatment with sigma1 receptor antagonists reduces formalin-induced phosphorylation of NMDA receptor subunit 1 and the second phase of formalin test in miceSigma receptors: from molecule to man.The cell death response to gamma-radiation in MCF-7 cells is enhanced by a neuroleptic drug, pimozide.Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays(+)-Morphine and (-)-morphine stereoselectively attenuate the (-)-morphine-produced tail-flick inhibition via the naloxone-sensitive sigma receptor in the ventral periaqueductal gray of the rat.Radioligands for the dopamine receptor subtypes.Differential modulation by cations of sigma and phencyclidine binding sites in rat brain.Solubilization and characterization of sigma-receptors from guinea pig brain membranes.Role of the sigma receptor in the inhibition of [3H]-noradrenaline uptake in brain synaptosomes and adrenal chromaffin cells.The glycine/NMDA receptor antagonist, R-(+)-HA-966, blocks activation of the mesolimbic dopaminergic system induced by phencyclidine and dizocilpine (MK-801) in rodents.Differentiation of [3H]phencyclidine and (+)-[3H]SKF-10,047 binding sites in rat cerebral cortex.A comparison of the binding of sigma opioids and phencyclidine, and the interaction with antipsychotic drugs in rat brain membranes.Effects of sigma ligands on the cloned mu-, delta- and kappa-opioid receptors co-expressed with G-protein-activated K+ (GIRK) channel in Xenopus oocytes.Effects of the psychotomimetic benzomorphan N-allylnormetazocine (SKF 10,047) on prepulse inhibition of startle in mice.Enhancement of immobility in a forced swimming test by subacute or repeated treatment with phencyclidine: a new model of schizophrenia.Chiral resolution of serial potent and selective σ1 ligands and biological evaluation of (-)-[18F]TZ3108 in rodent and the nonhuman primate brain.Dose-dependent sigma-1 receptor occupancy by donepezil in rat brain can be assessed with (11)C-SA4503 and microPET.Synthesis and evaluation of optically pure [3H]-(+)-pentazocine, a highly potent and selective radioligand for sigma receptors.Haloperidol inhibits maternal retrieval and licking, but enhances nursing behavior and litter weight gains in lactating rats.The sigma agonist 1,3-di-o-tolyl-guanidine reduces the morphological and behavioral changes induced by neonatal ventral hippocampus lesion in rats.Structure-Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma.3D Homology Model of Sigma1 Receptor.Pharmacological profiling of sigma 1 receptor ligands by novel receptor homomer assays.Use of the harmonic mean to the determination of dissociation constants of stereoisomeric mixtures of biologically active compounds.
P2860
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P2860
Sigma opiates and certain antipsychotic drugs mutually inhibit (+)-[3H] SKF 10,047 and [3H]haloperidol binding in guinea pig brain membranes
description
1984 nî lūn-bûn
@nan
1984 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1984 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
name
Sigma opiates and certain anti ...... in guinea pig brain membranes
@ast
Sigma opiates and certain anti ...... in guinea pig brain membranes
@en
Sigma opiates and certain anti ...... in guinea pig brain membranes
@nl
type
label
Sigma opiates and certain anti ...... in guinea pig brain membranes
@ast
Sigma opiates and certain anti ...... in guinea pig brain membranes
@en
Sigma opiates and certain anti ...... in guinea pig brain membranes
@nl
prefLabel
Sigma opiates and certain anti ...... in guinea pig brain membranes
@ast
Sigma opiates and certain anti ...... in guinea pig brain membranes
@en
Sigma opiates and certain anti ...... in guinea pig brain membranes
@nl
P2860
P3181
P356
P1476
Sigma opiates and certain anti ...... in guinea pig brain membranes
@en
P2860
P304
P3181
P356
10.1073/PNAS.81.17.5618
P407
P577
1984-09-01T00:00:00Z